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> Main
CHEBI:3887 - (−)-coronaridine
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ChEBI Name
(−)-coronaridine
ChEBI ID
CHEBI:3887
ChEBI ASCII Name
(-)-coronaridine
Definition
A monoterpenoid indole alkaloid with formula C
21
H
26
N
2
O
2
. It is isolated from the flowering plant genus,
Tabernaemontana
.
Stars
This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Molfile
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Wikipedia
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Read full article at Wikipedia
Formula
C21H26N2O2
Net Charge
0
Average Mass
338.451
Monoisotopic Mass
338.19943
InChI
InChI=1S/C21H26N2O2/c1-
3-
14-
10-
13-
11-
21(20(24)
25-
2)
18-
16(8-
9-
23(12-
13)
19(14)
21)
15-
6-
4-
5-
7-
17(15)
22-
18/h4-
7,13-
14,19,22H,3,8-
12H2,1-
2H3/t13-
,14+,19+,21-
/m1/s1
InChIKey
NVVDQMVGALBDGE-PZXGUROGSA-N
SMILES
[C@@]12([C@@]3([C@H](C[C@](C1)(CN3CCC=4C5=C(C=CC=C5)NC42)[H])CC)[H])C(OC)=O
Metabolite of Species
Details
Peschiera australis
(IPNI:1083767-2)
Found in stem
(BTO:0001300)
. See:
PubMed
Tabernaemontana ternifolia
(IPNI:60439757-2)
Found in root
(BTO:0001188)
. See:
PubMed
Ervatamia pandacaqui
(IPNI:78961-1)
Found in leaf
(BTO:0000713)
. See:
PubMed
Tabernaemontana heyneana
(IPNI:82149-1)
Found in root
(BTO:0001188)
. See:
PubMed
Tabernaemontana litoralis
(NCBI:txid403118)
Found in fruit
(BTO:0000486)
. See:
PubMed
Tabernaemontana catharinensis
(NCBI:txid403124)
Found in root
(BTO:0001188)
. Isolated from root bark. See:
PubMed
Tabernaemontana divaricata
(NCBI:txid52861)
Found in cell suspension culture
(BTO:0000221)
. See:
PubMed
Tabernaemontana divaricata
(NCBI:txid52861)
Found in aerial part
(BTO:0001658)
. See:
PubMed
Tabernaemontana pandacaqui
(NCBI:txid761085)
See:
PubMed
Tabernaemontana penduliflora
(NCBI:txid761088)
Found in seed
(BTO:0001226)
. See:
PubMed
Roles Classification
Biological Role
(s):
antileishmanial agent
An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus
Leishmania
.
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via
alkaloid
)
Application
(s):
antileishmanial agent
An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus
Leishmania
.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
(−)-coronaridine (
CHEBI:3887
)
has role
antileishmanial agent (
CHEBI:70868
)
(−)-coronaridine (
CHEBI:3887
)
has role
antineoplastic agent (
CHEBI:35610
)
(−)-coronaridine (
CHEBI:3887
)
has role
apoptosis inducer (
CHEBI:68495
)
(−)-coronaridine (
CHEBI:3887
)
has role
plant metabolite (
CHEBI:76924
)
(−)-coronaridine (
CHEBI:3887
)
is a
alkaloid ester (
CHEBI:38481
)
(−)-coronaridine (
CHEBI:3887
)
is a
methyl ester (
CHEBI:25248
)
(−)-coronaridine (
CHEBI:3887
)
is a
monoterpenoid indole alkaloid (
CHEBI:65323
)
(−)-coronaridine (
CHEBI:3887
)
is a
organic heteropentacyclic compound (
CHEBI:38164
)
(−)-coronaridine (
CHEBI:3887
)
is conjugate base of
(−)-coronaridine(1+) (
CHEBI:146232
)
Incoming
10-hydroxycoronaridine (
CHEBI:146256
)
has functional parent
(−)-coronaridine (
CHEBI:3887
)
(−)-coronaridine(1+) (
CHEBI:146232
)
is conjugate acid of
(−)-coronaridine (
CHEBI:3887
)
IUPAC Name
methyl ibogamine-18-carboxylate
Synonyms
Sources
(−)-coronaridine
KEGG COMPOUND
coronaridine
KEGG COMPOUND
Manual Xrefs
Databases
C00001709
KNApSAcK
C09139
KEGG COMPOUND
Coronaridine
Wikipedia
View more database links
Registry Number
Type
Source
467-77-6
CAS Registry Number
ChemIDplus
Citations
Types
Sources
11302794
PubMed citation
Europe PMC
12069962
PubMed citation
Europe PMC
1211783
PubMed citation
Europe PMC
14122038
PubMed citation
Europe PMC
17265301
PubMed citation
Europe PMC
17342619
PubMed citation
Europe PMC
23569415
PubMed citation
Europe PMC
26022277
PubMed citation
Europe PMC
26231157
PubMed citation
Europe PMC
28006917
PubMed citation
Europe PMC
29728039
PubMed citation
Europe PMC
30618175
PubMed citation
Europe PMC
30773907
PubMed citation
Europe PMC
31095891
PubMed citation
Europe PMC
4714135
PubMed citation
Europe PMC
7820611
PubMed citation
Europe PMC
Last Modified
06 March 2020