CHEBI:68847 - azilsartan kamedoxomil

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ChEBI Name azilsartan kamedoxomil
ChEBI ID CHEBI:68847
Definition An organic potassium salt that is the monopotassium salt of azilsartan medoxomil. A prodrug for azilsartan, it is used for treatment of hypertension.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C30H23KN4O8
Net Charge 0
Average Mass 606.62390
Monoisotopic Mass 606.11530
InChI InChI=1S/C30H24N4O8.K/c1-3-38-28-31-23-10-6-9-22(27(35)39-16-24-17(2)40-30(37)41-24)25(23)34(28)15-18-11-13-19(14-12-18)20-7-4-5-8-21(20)26-32-29(36)42-33-26;/h4-14H,3,15-16H2,1-2H3,(H,32,33,36);/q;+1/p-1
InChIKey IHWFKDWIUSZLCJ-UHFFFAOYSA-M
SMILES [K+].CCOc1nc2cccc(C(=O)OCc3oc(=O)oc3C)c2n1Cc1ccc(cc1)-c1ccccc1-c1noc(=O)[n-]1
Roles Classification
Biological Role(s): angiotensin receptor antagonist
A hormone antagonist that blocks angiotensin receptors.
Application(s): prodrug
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
angiotensin receptor antagonist
A hormone antagonist that blocks angiotensin receptors.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing azilsartan kamedoxomil (CHEBI:68847) has part azilsartan medoxomil(1−) (CHEBI:68849)
azilsartan kamedoxomil (CHEBI:68847) has role angiotensin receptor antagonist (CHEBI:61016)
azilsartan kamedoxomil (CHEBI:68847) has role antihypertensive agent (CHEBI:35674)
azilsartan kamedoxomil (CHEBI:68847) has role prodrug (CHEBI:50266)
azilsartan kamedoxomil (CHEBI:68847) is a organic potassium salt (CHEBI:50394)
IUPAC Name
potassium 3-{4'-[(2-ethoxy-7-{[(5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy]carbonyl}-1H-benzimidazol-1-yl)methyl]biphenyl-2-yl}-5-oxo-1,2,4-oxadiazol-4-ide
Synonym Source
TAK-491 ChemIDplus
Brand Name Source
Edarbi KEGG DRUG
Manual Xrefs Databases
D08865 KEGG DRUG
US2005187269 Patent
WO2012107814 Patent
View more database links
Registry Numbers Types Sources
12331024 Reaxys Registry Number Reaxys
863031-24-7 CAS Registry Number KEGG DRUG
Last Modified
15 November 2012