CHEBI:197341 - GYS32661

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ChEBI Name GYS32661
ChEBI ID CHEBI:197341
Definition A member of the class of quinolines that is quinoline substituted by (5-{4-[(morpholin-4-yl)methyl]-1H-imidazol-1-yl}pentyl)sulfanediyl and trifluoromethyl groups at positions 4 and 7, respectively. It is a Rac inhibitor that inhibits both Rac1 and Rac1b.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Stan Laulederkind
Supplier Information
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Formula C23H27F3N4OS
Net Charge 0
Average Mass 464.550
Monoisotopic Mass 464.18577
InChI InChI=1S/C23H27F3N4OS/c24-23(25,26)18-4-5-20-21(14-18)27-7-6-22(20)32-13-3-1-2-8-30-16-19(28-17-30)15-29-9-11-31-12-10-29/h4-7,14,16-17H,1-3,8-13,15H2
InChIKey UEZJAHLAEKXBTP-UHFFFAOYSA-N
SMILES FC(F)(F)C1=CC2=NC=CC(SCCCCCN3C=NC(CN4CCOCC4)=C3)=C2C=C1
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): Rac1 inhibitor
Any inhibitor of Rac1.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing GYS32661 (CHEBI:197341) has role antineoplastic agent (CHEBI:35610)
GYS32661 (CHEBI:197341) has role Rac1 inhibitor (CHEBI:197347)
GYS32661 (CHEBI:197341) is a aryl sulfide (CHEBI:35683)
GYS32661 (CHEBI:197341) is a imidazoles (CHEBI:24780)
GYS32661 (CHEBI:197341) is a morpholines (CHEBI:38785)
GYS32661 (CHEBI:197341) is a organofluorine compound (CHEBI:37143)
GYS32661 (CHEBI:197341) is a quinolines (CHEBI:26513)
GYS32661 (CHEBI:197341) is a tertiary amino compound (CHEBI:50996)
IUPAC Name
4-({5-[4-(morpholin-4-ylmethyl)-1H-imidazol-1-yl]pentyl}sulfanyl)-7-(trifluoromethyl)quinoline
Synonyms Sources
4-((1-(5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)-1H-imidazol-4-yl)methyl)morpholine ChEBI
GYS 32661 ChEBI
GYS-32661 SUBMITTER
Registry Number Type Source
2589092-11-3 CAS Registry Number SUBMITTER
Citations Waiting for Citations Types Sources
30926638 PubMed citation SUBMITTER
35740379 PubMed citation Europe PMC
35853497 PubMed citation SUBMITTER
37664052 PubMed citation Europe PMC
Last Modified
25 September 2023