CHEBI:59273 - dexbrompheniramine maleate

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ChEBI Name dexbrompheniramine maleate
ChEBI ID CHEBI:59273
Definition The maleic acid salt of the (pharmacologically active) (S)-(+)-enantiomer of brompheniramine. A histamine H1 receptor antagonist, it is used for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C20H23BrN2O4
Net Charge 0
Average Mass 435.31200
Monoisotopic Mass 434.08412
InChI InChI=1S/C16H19BrN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-;/m0./s1
InChIKey SRGKFVAASLQVBO-DASCVMRKSA-N
SMILES OC(=O)\C=C/C(O)=O.CN(C)CC[C@@H](c1ccc(Br)cc1)c1ccccn1
Roles Classification
Biological Role(s): H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
Application(s): H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
anti-allergic agent
A drug used to treat allergic reactions.
(via brompheniramine maleate )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing dexbrompheniramine maleate (CHEBI:59273) has part dexbrompheniramine (CHEBI:59269)
dexbrompheniramine maleate (CHEBI:59273) has role anti-allergic agent (CHEBI:50857)
dexbrompheniramine maleate (CHEBI:59273) has role H1-receptor antagonist (CHEBI:37955)
dexbrompheniramine maleate (CHEBI:59273) is a brompheniramine maleate (CHEBI:3184)
IUPAC Name
(3S)-3-(4-bromophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine (2Z)-but-2-enedioate
Synonyms Sources
(+)-2-(p-bromo-α-(2-dimethylaminoethyl)benzyl)pyridine maleate ChEBI
(+)-3-(4-bromophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine maleate ChEBI
(+)-3-(4-bromophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine maleate ChEBI
(+)-3-(p-bromophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine maleate ChEBI
(+)-brompheniramine maleate ChEBI
(3S)-3-(4-bromophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine maleate ChEBI
(S)-1-(p-bromophenyl)-1-(2-pyridyl)-3-dimethylaminopropane maleate ChEBI
(S)-2-(p-bromo-α-(2-dimethylaminoethyl)benzyl)pyridine maleate ChEBI
(S)-3-(4-bromophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine maleate ChEBI
(S)-3-(4-bromophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine maleate ChEBI
(S)-3-(p-bromophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine maleate ChEBI
Manual Xrefs Databases
D03704 KEGG DRUG
DB00405 DrugBank
View more database links
Registry Number Type Source
2391-03-9 CAS Registry Number ChemIDplus
Last Modified
23 April 2010