CHEBI:229648 - flotufolastat F-18

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ChEBI Name flotufolastat F-18 ChEBI ID CHEBI:229648 Definition An 18F radiopharmaceutical which is used as a radioactive diagnostic agent for positron emission tomography (PET) of prostate-specific membrane antigen positive lesions in men with prostate cancer. Stars This entity has been manually annotated by the ChEBI Team. Supplier Information Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Wikipedia License Read full article at Wikipedia Formula C63H99[18F]N12O25Si Net Charge 0 Average Mass 1470.630 Monoisotopic Mass 1469.66230 InChI InChI=1S/C63H99FN12O25Si/c1-62(2,3)102(64,63(4,5)6)39-14-12-38(13-15-39)54(89)67-34-44(69-49(80)20-18-45(60(99)100)76-32-30-74(36-52(85)86)28-26-73(35-51(83)84)27-29-75(31-33-76)37-53(87)88)55(90)70-41(57(93)94)10-7-8-24-65-46(77)21-22-47(78)66-25-9-11-40(56(91)92)68-48(79)19-16-42(58(95)96)71-61(101)72-43(59(97)98)17-23-50(81)82/h12-15,40-45H,7-11,16-37H2,1-6H3,(H,65,77)(H,66,78)(H,67,89)(H,68,79)(H,69,80)(H,70,90)(H,81,82)(H,83,84)(H,85,86)(H,87,88)(H,91,92)(H,93,94)(H,95,96)(H,97,98)(H,99,100)(H2,71,72,101)/t40-,41-,42+,43+,44-,45+/m1/s1/i64-1 InChIKey QMGJNAVROCDAIW-MQNQVPOESA-N SMILES CC(C)(C)[Si]([18F])(C1=CC=C(C=C1)C(=O)NC[C@@H](NC(=O)CC[C@H](N1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1)C(O)=O)C(=O)N[C@H](CCCCNC(=O)CCC(=O)NCCC[C@@H](NC(=O)CC[C@H](NC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O)C(O)=O)C(O)=O)C(C)(C)C Roles Classification Application(s): radioactive imaging agent radiopharmaceutical Any pharmaceutical compound containing a radioisotope. (via (18)F radiopharmaceutical ) View more via ChEBI Ontology ChEBI Ontology Outgoing flotufolastat F-18 (CHEBI:229648) has role radioactive imaging agent (CHEBI:37336) flotufolastat F-18 (CHEBI:229648) is a 18F radiopharmaceutical (CHEBI:49127) flotufolastat F-18 (CHEBI:229648) is a benzamides (CHEBI:22702) flotufolastat F-18 (CHEBI:229648) is a crown amine (CHEBI:37411) flotufolastat F-18 (CHEBI:229648) is a organosiloxane (CHEBI:48150) flotufolastat F-18 (CHEBI:229648) is a secondary carboxamide (CHEBI:140325) flotufolastat F-18 (CHEBI:229648) is conjugate acid of flotufolastat F-18(9−) (CHEBI:229676) Incoming flotufolastat F-18(9−) (CHEBI:229676) is conjugate base of flotufolastat F-18 (CHEBI:229648) IUPAC Name N-{(4S)-4-carboxy-4-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl]butanoyl}-3-(4-{di-tert-butyl[(18F)fluoro]silyl}benzamido)-D-alanyl-N6-[4-({(4R)-4-carboxy-4-[(N-{[(1S)-1,3-dicarboxypropyl]carbamoyl}-L-γ-glutamyl)amino]butyl}amino)-4-oxobutanoyl]-D-lysine INNs Sources flotufolastat (18F) WHO MedNet flotufolastat (18F) WHO MedNet flotufolastat (18F) WHO MedNet flotufolastatum (18F) WHO MedNet Synonyms Sources 18F-rhPSMA-7.3 DrugBank flotufolastat (18F) DrugBank flotufolastat 18F ChEBI flotufolastat F 18 DrugBank Manual Xrefs Databases DB17851 DrugBank Flotufolastat_F-18 Wikipedia View more database links Registry Number Type Source 2639294-14-5 CAS Registry Number DrugBank Citations Types Sources 33067338 PubMed citation Europe PMC 33846844 PubMed citation Europe PMC 35119557 PubMed citation Europe PMC 35393348 PubMed citation Europe PMC 36416908 PubMed citation Europe PMC 37439946 PubMed citation Europe PMC 37932609 PubMed citation Europe PMC Last Modified 23 February 2024