CHEBI:80144 - kinetensin

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ChEBI Name kinetensin ChEBI ID CHEBI:80144 Definition An oligopeptide comprising of nine amino acids with sequence L-Ile-L-Ala-L-Arg-L-Arg-L-His-L-Pro-L-Tyr-L-Phe-L-Leu. It was originally isolated from pepsin-treated human plasma and shares some sequence homology with the C-terminal end of neurotensin. It is a potent histamine releaser and may serve as an inflammatory mediator. Stars This entity has been manually annotated by the ChEBI Team. Supplier Information Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Formula C56H85N17O11 Net Charge 0 Average Mass 1172.404 Monoisotopic Mass 1171.66145 InChI InChI=1S/C56H85N17O11/c1-6-32(4)45(57)52(81)66-33(5)46(75)67-38(15-10-22-63-55(58)59)47(76)68-39(16-11-23-64-56(60)61)48(77)71-42(28-36-29-62-30-65-36)53(82)73-24-12-17-44(73)51(80)70-41(27-35-18-20-37(74)21-19-35)49(78)69-40(26-34-13-8-7-9-14-34)50(79)72-43(54(83)84)25-31(2)3/h7-9,13-14,18-21,29-33,38-45,74H,6,10-12,15-17,22-28,57H2,1-5H3,(H,62,65)(H,66,81)(H,67,75)(H,68,76)(H,69,78)(H,70,80)(H,71,77)(H,72,79)(H,83,84)(H4,58,59,63)(H4,60,61,64)/t32-,33-,38-,39-,40-,41-,42-,43-,44-,45-/m0/s1 InChIKey PANUJGMSOSQAAY-IHXGQVBNSA-N SMILES C([C@H](CC(C)C)NC([C@H](CC1=CC=CC=C1)NC([C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H]3N(CCC3)C([C@@H](NC([C@H](CCCNC(=N)N)NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H]([C@H](CC)C)N)=O)=O)=O)=O)CC4=CN=CN4)=O)=O)=O)(=O)O Metabolite of Species Details Homo sapiens (NCBI:txid9606) Found in blood plasma (BTO_0000131). See: PubMed Roles Classification Chemical Role(s): Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound ) Biological Role(s): human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). histamine releasing agent Any substance that can induce the release of histamine from mast cells. View more via ChEBI Ontology ChEBI Ontology Outgoing kinetensin (CHEBI:80144) has role histamine releasing agent (CHEBI:75298) kinetensin (CHEBI:80144) has role human metabolite (CHEBI:77746) kinetensin (CHEBI:80144) is a oligopeptide (CHEBI:25676) kinetensin (CHEBI:80144) is conjugate base of kinetensin(2+) (CHEBI:147364) Incoming kinetensin(2+) (CHEBI:147364) is conjugate acid of kinetensin (CHEBI:80144) IUPAC Name L-isoleucyl-L-alanyl-L-arginyl-L-arginyl-L-histidyl-L-prolyl-L-tyrosyl-L-phenylalanyl-L-leucine Synonyms Sources H-Ile-Ala-Arg-Arg-His-Pro-Tyr-Phe-Leu-OH ChEBI I-A-R-R-H-P-Y-F-L ChEBI IARRHPYFL ChEBI Ile-Ala-Arg-Arg-His-Pro-Tyr-Phe-Leu KEGG COMPOUND kinetensin (human) ChEBI L-Ile-L-Ala-L-Arg-L-Arg-L-His-L-Pro-L-Tyr-L-Phe-L-Leu ChEBI Manual Xrefs Databases C15872 KEGG COMPOUND FDB029235 FooDB HMDB0012988 HMDB WO2009040022 Patent View more database links Registry Number Type Source 103131-69-7 CAS Registry Number ChemIDplus Citations Types Sources 1800960 PubMed citation Europe PMC 2117773 PubMed citation Europe PMC 23802150 PubMed citation Europe PMC 2437111 PubMed citation Europe PMC 2473637 PubMed citation Europe PMC 3087352 PubMed citation Europe PMC 8013539 PubMed citation Europe PMC 8213349 PubMed citation Europe PMC Last Modified 20 April 2020