CHEBI:183809 - 7β-hydroxyepiandrosterone

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ChEBI Name 7β-hydroxyepiandrosterone
ChEBI ID CHEBI:183809
ChEBI ASCII Name 7beta-hydroxyepiandrosterone
Definition A 3β-hydroxy steroid that is epiandrosterone carrying a hydroxy group at the 7β position. It is an endogenous androgen metabolite that has been shown to exert neuroprotective effects.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Lucila Aimo
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Formula C19H30O3
Net Charge 0
Average Mass 306.446
Monoisotopic Mass 306.21949
InChI InChI=1S/C19H30O3/c1-18-7-5-12(20)9-11(18)10-15(21)17-13-3-4-16(22)19(13,2)8-6-14(17)18/h11-15,17,20-21H,3-10H2,1-2H3/t11-,12+,13+,14+,15+,17+,18+,19+/m1/s1
InChIKey VFPMCLQMAUVEHD-UCPSWNCLSA-N
SMILES [H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])[C@@H](O)C[C@@]2([H])C[C@@H](O)CC[C@]12C
Metabolite of Species Details
Homo sapiens (NCBI:txid9606) Found in blood plasma (BTO:0000131). See: PubMed
Roles Classification
Biological Role(s): human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
estrogen receptor antagonist
An antagonist at the estrogen receptor.
androgen
A sex hormone that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors.
Application(s): neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
estrogen receptor antagonist
An antagonist at the estrogen receptor.
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ChEBI Ontology
Outgoing 7β-hydroxyepiandrosterone (CHEBI:183809) has functional parent epiandrosterone (CHEBI:541975)
7β-hydroxyepiandrosterone (CHEBI:183809) has role androgen (CHEBI:50113)
7β-hydroxyepiandrosterone (CHEBI:183809) has role estrogen receptor antagonist (CHEBI:50792)
7β-hydroxyepiandrosterone (CHEBI:183809) has role human metabolite (CHEBI:77746)
7β-hydroxyepiandrosterone (CHEBI:183809) has role neuroprotective agent (CHEBI:63726)
7β-hydroxyepiandrosterone (CHEBI:183809) is a 17-oxo steroid (CHEBI:19168)
7β-hydroxyepiandrosterone (CHEBI:183809) is a 3β-hydroxy steroid (CHEBI:36836)
7β-hydroxyepiandrosterone (CHEBI:183809) is a 7β-hydroxy steroid (CHEBI:35349)
7β-hydroxyepiandrosterone (CHEBI:183809) is a androstanoid (CHEBI:50402)
IUPAC Name
3β,7β-dihydroxy-5α-androstan-17-one
Synonyms Sources
(3β,5α,7β)-3,7-dihydroxyandrostan-17-one ChemIDplus
3β,7β-dihydroxy-5α-androstan-17-one UniProt
7-beta-hydroxyepiandrosterone ChemIDplus
7β-hydroxy-epiandrosterone ChEBI
7β-OH-EPIA ChemIDplus
HF-0220 ChemIDplus
HF0220 DrugBank
Manual Xrefs Databases
7%CE%B2-Hydroxyepiandrosterone Wikipedia
8011902 ChemSpider
DB06622 DrugBank
HMDB0259631 HMDB
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Registry Number Type Source
25848-69-5 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
12859344 PubMed citation Europe PMC
15006696 PubMed citation Europe PMC
17593962 PubMed citation SUBMITTER
17624766 PubMed citation Europe PMC
18502118 PubMed citation Europe PMC
18555503 PubMed citation Europe PMC
18996481 PubMed citation Europe PMC
26023144 PubMed citation Europe PMC
28948821 PubMed citation Europe PMC
30484677 PubMed citation Europe PMC
Last Modified
18 November 2021