CHEBI:197423 - W54011

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ChEBI Name W54011
ChEBI ID CHEBI:197423
Definition Potent, specific and orally active C5a receptor antagonist
Stars This entity has been manually annotated by a third party.
Submitter Jonathan Muyskens
Supplier Information
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Formula C30H36N2O2.ClH
Net Charge 0
Average Mass 493.090
Monoisotopic Mass 492.25436
InChI InChI=1S/C30H36N2O2.ClH/c1-21(2)23-11-16-26(17-12-23)32(20-22-9-14-25(15-10-22)31(3)4)30(33)28-8-6-7-24-13-18-27(34-5)19-29(24)28;/h9-19,21,28H,6-8,20H2,1-5H3;1H
InChIKey UKBJWRMNGCDKNL-UHFFFAOYSA-N
SMILES Cl.COC1=CC2=C(CCCC2C(=O)N(CC2=CC=C(C=C2)N(C)C)C2=CC=C(C=C2)C(C)C)C=C1
Roles Classification
Biological Role(s): C5a receptor antagonist
Any antagonist of the C5a receptor.
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing W54011 (CHEBI:197423) has role anti-inflammatory agent (CHEBI:67079)
W54011 (CHEBI:197423) has role C5a receptor antagonist (CHEBI:144895)
W54011 (CHEBI:197423) is a hydrochloride (CHEBI:36807)
IUPAC Name
N-[4-(dimethylamino)benzyl]-7-methoxy-N-[4-(propan-2-yl)phenyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide hydrochloride
Synonyms Sources
C5a receptor antagonist, W-54011 ChEBI
N-((4-dimethylaminophenyl)methyl)-N-(4-isopropylphenyl)-7-methoxy-1,2,3,4-tetrahydronaphthalen-1-carboxamide hydrochloride SUBMITTER
W 54011 ChEBI
W-54011 ChEBI
Registry Number Type Source
405098-33-1 CAS Registry Number SUBMITTER
Citations Waiting for Citations Types Sources
20217457 PubMed citation Europe PMC
29300009 PubMed citation Europe PMC
31408672 PubMed citation Europe PMC
31510052 PubMed citation Europe PMC
33714207 PubMed citation Europe PMC
34030523 PubMed citation Europe PMC
36732060 PubMed citation Europe PMC
36753088 PubMed citation Europe PMC
37271327 PubMed citation Europe PMC
Last Modified
31 October 2023