apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
EC 2.5.1.58 (protein farnesyltransferase) inhibitor
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of protein farnesyltransferase (EC 2.5.1.58), one of the three enzymes in the prenyltransferase group.
GABA modulator
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
(via benzodiazepine )
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antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
GABA modulator
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
(via benzodiazepine )
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(3R)- 3- benzyl- 1- (1H- imidazol- 5- ylmethyl)- 4- (thiophen- 2- ylsulfonyl)- 2,3,4,5- tetrahydro- 1H- 1,4- benzodiazepine- 7- carbonitrile
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(3R)- 3- benzyl- 1- (1H- imidazol- 5- ylmethyl)- 4- thiophen- 2- ylsulfonyl- 3,5- dihydro- 2H- 1,4- benzodiazepine- 7- carbonitrile
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ChEBI
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(R)- 2,3,4,5- tetrahydro- 1- (1H- imidazol- 4- ylmethyl)- 3- (phenylmethyl)- 4- (2- thienylsulfonyl)- 1H- 1,4- benzodiazepine- 7- carbonitrile
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ChEBI
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(R)- 7- cyano- 2,3,4,5- tetrahydro- 1- (1H- imidazol- 4- ylmethyl)- 3- (phenylmethyl)- 4- (2- thienylsulfonyl)- 1H- 1,4- benzodiazepine
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ChEBI
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BMS 214662
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ChemIDplus
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BMS214662
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ChemIDplus
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