CHEBI:156336 - 3'-deoxy-3',4'-didehydro-CTP

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ChEBI Name 3'-deoxy-3',4'-didehydro-CTP
ChEBI ID CHEBI:156336
Definition An organic triphosphate resulting from the formal condensation of the 5'-hydroxy group of 3'-deoxy-3',4'-didehydro-cytidine with triphosphoric acid. It is a chain terminator for RNA-dependent RNA polymerases.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Mark Williams
Supplier Information
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Formula C9H14N3O13P3
Net Charge 0
Average Mass 465.140
Monoisotopic Mass 464.97395
InChI InChI=1S/C9H14N3O13P3/c10-7-1-2-12(9(14)11-7)8-6(13)3-5(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-3,6,8,13H,4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17)/t6-,8-/m1/s1
InChIKey DGUQXKKDZHTKIE-HTRCEHHLSA-N
SMILES NC1=NC(=O)N(C=C1)[C@@H]1OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)=C[C@H]1O
Roles Classification
Biological Role(s): antimetabolite
A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.
antiviral agent
A substance that destroys or inhibits replication of viruses.
EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor
A DNA polymerase inhibitor that interferes with the action of a RNA-directed RNA polymerase (EC 2.7.7.48).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 3'-deoxy-3',4'-didehydro-CTP (CHEBI:156336) has functional parent 3'-deoxy-3',4'-didehydro-cytidine (CHEBI:156331)
3'-deoxy-3',4'-didehydro-CTP (CHEBI:156336) has role antimetabolite (CHEBI:35221)
3'-deoxy-3',4'-didehydro-CTP (CHEBI:156336) has role antiviral agent (CHEBI:22587)
3'-deoxy-3',4'-didehydro-CTP (CHEBI:156336) has role EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor (CHEBI:170010)
3'-deoxy-3',4'-didehydro-CTP (CHEBI:156336) is a organic triphosphate (CHEBI:62894)
3'-deoxy-3',4'-didehydro-CTP (CHEBI:156336) is a pyrimidone (CHEBI:38337)
3'-deoxy-3',4'-didehydro-CTP (CHEBI:156336) is conjugate acid of 3'-deoxy-3',4'-didehydro-CTP(4−) (CHEBI:166821)
Incoming 3'-deoxy-3',4'-didehydro-CTP(4−) (CHEBI:166821) is conjugate base of 3'-deoxy-3',4'-didehydro-CTP (CHEBI:156336)
IUPAC Name
({[({[(4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-4,5-dihydrofuran-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid
Synonyms Sources
3'-deoxy-3',4'-didehydro-cytidine triphosphate ChEBI
3'-deoxy-3',4'-didehydro-cytidine-5'-triphosphate ChEBI
[[(2R,3R)-2-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxy-2,3-dihydrofuran-5-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate IUPAC
ddh-CTP SUBMITTER
ddhC-triphosphate ChEBI
ddhCTP ChEBI
Manual Xref Database
107448068 ChemSpider
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Last Modified
19 January 2023