CHEBI:4601 - diloxanide furoate

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ChEBI Name diloxanide furoate
ChEBI ID CHEBI:4601
Definition A carboxylic ester resulting from the formal condensation of the carboxy group of furan-2-carboxylic acid with the hydroxy group of 2,2-dichloro-N-(4-hydroxyphenyl)-N-methylacetamide. It is a drug used for the treatment of asymptomatic amebiasis.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C14H11Cl2NO4
Net Charge 0
Average Mass 328.150
Monoisotopic Mass 327.00651
InChI InChI=1S/C14H11Cl2NO4/c1-17(13(18)12(15)16)9-4-6-10(7-5-9)21-14(19)11-3-2-8-20-11/h2-8,12H,1H3
InChIKey BDYYDXJSHYEDGB-UHFFFAOYSA-N
SMILES CN(C(=O)C(Cl)Cl)C1=CC=C(OC(=O)C2=CC=CO2)C=C1
Roles Classification
Application(s): antiamoebic agent
An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae.
prodrug
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
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ChEBI Ontology
Outgoing diloxanide furoate (CHEBI:4601) has role antiamoebic agent (CHEBI:171664)
diloxanide furoate (CHEBI:4601) has role prodrug (CHEBI:50266)
diloxanide furoate (CHEBI:4601) is a carboxylic ester (CHEBI:33308)
diloxanide furoate (CHEBI:4601) is a furans (CHEBI:24129)
diloxanide furoate (CHEBI:4601) is a organochlorine compound (CHEBI:36683)
diloxanide furoate (CHEBI:4601) is a tertiary carboxamide (CHEBI:140326)
IUPAC Name
4-[(dichloroacetyl)(methyl)amino]phenyl furan-2-carboxylate
Synonyms Sources
8073 CB ChemIDplus
CB 8073 ChemIDplus
diloxanid furoate DrugCentral
diloxanide furoate KEGG COMPOUND
entamide furoate DrugCentral
Brand Names Sources
Amebiazol ChemIDplus
Dichlofurazol DrugCentral
Diclofurazol ChemIDplus
Furamide ChemIDplus
Furentomin ChemIDplus
Histomibal ChemIDplus
Miforon ChemIDplus
Manual Xrefs Databases
18400 ChemSpider
896 DrugCentral
C07637 KEGG COMPOUND
D02480 KEGG DRUG
DB14638 DrugBank
Diloxanide Wikipedia
HMDB0015684 HMDB
LSM-2223 LINCS
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Registry Number Type Source
3736-81-0 CAS Registry Number ChemIDplus
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Last Modified
28 April 2021