Services
Research
Training
Industry
About us
ChEBI
Examples:
iron*
,
InChI=1S/CH4O/c1-2/h2H,1H3
,
caffeine
Advanced
Home
Advanced Search
Browse
Documentation
Download
Tools
About ChEBI
Submit
Contact us
DiNA
Statistics
Entity of the Month
Periodic Table
Ontology
Train online
User Manual
Annotation Manual
Developer Manual
FAQ's
BiNChE
libChEBI
Web Services
ChEBI
> Main
CHEBI:51368 - lofexidine
Main
ChEBI Ontology
Automatic Xrefs
Reactions
Pathways
Models
ChEBI Name
lofexidine
ChEBI ID
CHEBI:51368
Stars
This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download
Molfile
XML
SDF
Find compounds which contain this structure
Find compounds which resemble this structure
Take structure to the Advanced Search
Formula
C11H12Cl2N2O
Net Charge
0
Average Mass
259.13126
Monoisotopic Mass
258.03267
InChI
InChI=1S/C11H12Cl2N2O/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13/h2-4,7H,5-6H2,1H3,(H,14,15)
InChIKey
KSMAGQUYOIHWFS-UHFFFAOYSA-N
SMILES
CC(Oc1c(Cl)cccc1Cl)C1=NCCN1
Roles Classification
Biological Role
(s):
alpha-adrenergic agonist
An agent that selectively binds to and activates
alpha
-adrenergic receptors.
Application
(s):
alpha-adrenergic agonist
An agent that selectively binds to and activates
alpha
-adrenergic receptors.
antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
lofexidine (
CHEBI:51368
)
has role
α-adrenergic agonist (
CHEBI:35569
)
lofexidine (
CHEBI:51368
)
has role
antihypertensive agent (
CHEBI:35674
)
lofexidine (
CHEBI:51368
)
is a
aromatic ether (
CHEBI:35618
)
lofexidine (
CHEBI:51368
)
is a
carboxamidine (
CHEBI:35359
)
lofexidine (
CHEBI:51368
)
is a
dichlorobenzene (
CHEBI:23697
)
lofexidine (
CHEBI:51368
)
is a
imidazoles (
CHEBI:24780
)
IUPAC Name
2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1
H
-imidazole
INNs
Sources
lofexidina
WHO MedNet
lofexidine
WHO MedNet
lofexidine
ChemIDplus
lofexidinum
WHO MedNet
Synonym
Source
2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazoline
ChemIDplus
Manual Xrefs
Databases
1593
DrugCentral
DB04948
DrugBank
DE1935479
Patent
LSM-4951
LINCS
US3966757
Patent
View more database links
Registry Numbers
Types
Sources
31036-80-3
CAS Registry Number
ChemIDplus
750704
Beilstein Registry Number
Beilstein
Last Modified
22 February 2017