CHEBI:4647 - dipivefrin hydrochloride

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ChEBI Name dipivefrin hydrochloride
ChEBI ID CHEBI:4647
Definition The hydrochloride salt of dipivefrin. It is used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C19H30ClNO5
Net Charge 0
Average Mass 387.89800
Monoisotopic Mass 387.18125
InChI InChI=1S/C19H29NO5.ClH/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6;/h8-10,13,20-21H,11H2,1-7H3;1H
InChIKey VKFAUCPBMAGVRG-UHFFFAOYSA-N
SMILES Cl.CNCC(O)c1ccc(OC(=O)C(C)(C)C)c(OC(=O)C(C)(C)C)c1
Roles Classification
Biological Role(s): adrenergic agonist
An agent that selectively binds to and activates adrenergic receptors.
sympathomimetic agent
A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
Application(s): adrenergic agonist
An agent that selectively binds to and activates adrenergic receptors.
sympathomimetic agent
A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
antiglaucoma drug
Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing dipivefrin hydrochloride (CHEBI:4647) has part dipivefrin(1+) (CHEBI:73714)
dipivefrin hydrochloride (CHEBI:4647) has role adrenergic agonist (CHEBI:37886)
dipivefrin hydrochloride (CHEBI:4647) has role antiglaucoma drug (CHEBI:39456)
dipivefrin hydrochloride (CHEBI:4647) has role sympathomimetic agent (CHEBI:35524)
dipivefrin hydrochloride (CHEBI:4647) is a hydrochloride (CHEBI:36807)
IUPAC Name
2-{3,4-bis[(2,2-dimethylpropanoyl)oxy]phenyl}-2-hydroxy-N-methylethanaminium chloride
Synonyms Sources
1-(3',4'-dipivaloyloxyphenyl)-2-methylamino-1-ethanol hydrochloride ChEBI
4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diyl bis(2,2-dimethylpropanoate) hydrochloride IUPAC
dipivefrin HCl ChemIDplus
dipivefrine HCl ChEBI
dipivefrine hydrochloride ChemIDplus
Manual Xrefs Databases
D01017 KEGG DRUG
DB00449 DrugBank
View more database links
Registry Numbers Types Sources
64019-93-8 CAS Registry Number KEGG DRUG
64019-93-8 CAS Registry Number ChemIDplus
6458483 Beilstein Registry Number Beilstein
Last Modified
20 May 2013