CHEBI:5292 - geldanamycin

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ChEBI Name geldanamycin
ChEBI ID CHEBI:5292
Definition An ansamycin consisting of a 19-membered macrocyle incorporating a benzoquinone ring and a lactam functionality. It shows antimicrobial activity against many Gram-positive and some Gram-negative bacteria.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:42670
Supplier Information
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Roles Classification
Biological Role(s): antiviral agent
A substance that destroys or inhibits replication of viruses.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
cysteine protease inhibitor
Any protease inhibitor that restricts the action of a cysteine protease.
Hsp90 inhibitor
An EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor that blocks the action of heat shock protein 90.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
Related Structures
geldanamycin is a Functional Parent of
tanespimycin
Mass : 585.690
Formula : C31H43N3O8
64153 		retaspimycin
Mass : 587.705
Formula : C31H45N3O8
71975 		alvespimycin
Mass : 616.747
Formula : C32H48N4O8
65324
geldanamycin is a Structural Derivative of
carbamic acid
Mass : 61.04006
Formula : CH3NO2
28616
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