CHEBI:17154 - nicotinamide

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ChEBI Name nicotinamide
ChEBI ID CHEBI:17154
Definition A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:44258, CHEBI:7556, CHEBI:14645, CHEBI:25521
Supplier Information
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Roles Classification
Chemical Role(s): antioxidant
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
Escherichia coli metabolite
Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
Saccharomyces cerevisiae metabolite
Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ).
EC 3.5.1.98 (histone deacetylase) inhibitor
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98).
Sir2 inhibitor
An EC 3.5.1.98 (histone deacetylase) inhibitor that interferes with the action of Sir2.
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of a NAD+ ADP-ribosyltransferase (EC 2.4.2.30).
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
human urinary metabolite
Any metabolite (endogenous or exogenous) found in human urine samples.
cofactor
An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).
water-soluble vitamin (role)
Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine.
(via B vitamin )
Application(s): neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
anti-inflammatory agent
Any compound that has anti-inflammatory effects.
geroprotector
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
nutraceutical
A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.
(via B vitamin )
Related Structures
nicotinamide is a Functional Parent of
Pestalamide C
Mass: 272.304
197575
Himeic acid G
Mass: 334.416
211171
Myxochelin O
Mass: 263.297
222138
Myxochelin N
Mass: 342.399
222142
Penipyridone A
Mass: 244.250
227809
Penipyridone C
Mass: 328.368
227819
Penipyridone D
Mass: 288.303
227822
Penipyridone F
Mass: 372.421
227832
Pestalamide D
Mass: 356.378
215530
6-Methylnicotinamide
Mass: 150.178
88954
nikethamide
Mass: 178.231
134814
Nicoxamat
Mass: 138.126
173404
N-methylnicotinamide
Mass: 136.15120
Formula: C7H8N2O
64399
nicorandil
Mass: 211.17480
Formula: C8H9N3O4
31905
nicotinamide is a Structural Derivative of
nicotinic acid
Mass : 123.10944
Formula : C6H5NO2
15940
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