Kanamycin kinase (M-CSA:640)

Proteins that are close homologues to the M-CSA reference protein and have the same catalytic residues (highlighted in green, below) probably share the same mechanism. Please also check if the homologue shares the same FunTree Structural Cluster and the same Pfam family, as another measure of similarity.

Legend:
Reference Residue Conserved Residue Non Conserved Residue Outside Alignment Reference Residue not in this chain

The residue id shown is the one in the PDB sequence. This may be different from the resid given by the author of the PDB file.

PDB sequences identical to 1l8t

In these PDB chains all the catalytic residues are conserved and have the same numbering as the reference.

2b0q(A), 3tm0(A)

PDB sequences homologous to 1l8t

Reference PDB chains/ identical chains Homologous PDB chains Asp208(207)A Asn195(194)A Lys44(43)A Asp190(189)A
1l8t(A)
PfamFunTree
3tm0(A)
PfamFunTree
2b0q(A)
PfamFunTree
4feu(E,F,B,D,A,C)
PfamFunTree
4gki(I,E,F,B,K,G,L,D,H,J,A,C)
PfamFunTree
4fev(E,F,B,D,A,C)
PfamFunTree
4gkh(I,E,K,B,F,G,L,D,H,J,A,C)
PfamFunTree
4few(E,F,B,D,A,C)
PfamFunTree
4fex(E,B,D,A,C)
PfamFunTree
Lys56 Asp199
1l8t(A)
PfamFunTree
3tm0(A)
PfamFunTree
2b0q(A)
PfamFunTree
4ej7(B,A,C)
PfamFunTree
Lys76 Asp219
1l8t(A)
PfamFunTree
3tm0(A)
PfamFunTree
2b0q(A)
PfamFunTree
1nd4(B,A)
PfamFunTree
Lys50 Asp190
1l8t(A)
PfamFunTree
3tm0(A)
PfamFunTree
2b0q(A)
PfamFunTree
4h05(B,A)
PfamFunTree
Lys48 Asp190
1l8t(A)
PfamFunTree
3tm0(A)
PfamFunTree
2b0q(A)
PfamFunTree
2bkk(A,C)
PfamFunTree
Lys44 Asp190
1l8t(A)
PfamFunTree
3tm0(A)
PfamFunTree
2b0q(A)
PfamFunTree
1l8t(A)
PfamFunTree
3tm0(A)
PfamFunTree
2b0q(A)
PfamFunTree
Lys43 Asp189
1l8t(A)
PfamFunTree
3tm0(A)
PfamFunTree
2b0q(A)
PfamFunTree
1j7i(A)
PfamFunTree
3q2j(B,A)
PfamFunTree
1j7u(B,A)
PfamFunTree
1j7l(B,A)
PfamFunTree
Lys44 Asp190
1l8t(A)
PfamFunTree
3tm0(A)
PfamFunTree
2b0q(A)
PfamFunTree
6fuc(A)
PfamFunTree
6fux(A)
PfamFunTree
x x