Finn group

Computational approaches to understanding microbiomes

Phylogenetic tree showing distribution of MAGs
Phylogenetic tree showing the distribution of novel specieis MAGs (green, inner) that we have recovered from human gut samples. The outering shows the different phyla.

The Finn research group focuses on developing computational approaches for the reconstruction of genomes from metagenomes, thereby enriching the tree of Life. The group will also investigate the distribution of microbes and functions in different environments, and probe the functions of so-called ‘microbial dark matter’.

 

 

Collaboration

We welcome new collaborations in all areas, and are particularly interested in working with people who have developed new tools for analysis, or who are working with metagenomics datasets generated with new sequencing technology.

Selected Publications

Microbial abundance, activity and population genomic profiling with mOTUs2.
Milanese A, Mende DR, Paoli L, Salazar G, Ruscheweyh HJ, Cuenca M, Hingamp P, Alves R, Costea PI, Coelho LP, Schmidt TSB, Almeida A, Mitchell AL, Finn RD, Huerta-Cepas J, Bork P, Zeller G, Sunagawa S. Nat Commun Volume 10 (2019) p.1014
A new genomic blueprint of the human gut microbiota.
Almeida A, Mitchell AL, Boland M, Forster SC, Gloor GB, Tarkowska A, Lawley TD, Finn RD. Nature Volume 568 (2019) p.499-504
A human gut bacterial genome and culture collection for improved metagenomic analyses.
Forster SC, Kumar N, Anonye BO, Almeida A, Viciani E, Stares MD, Dunn M, Mkandawire TT, Zhu A, Shao Y, Pike LJ, Louie T, Browne HP, Mitchell AL, Neville BA, Finn RD, Lawley TD. Nat Biotechnol Volume 37 (2019) p.186-192