Structure for tipranavir (A02.001 inhibitor)
| TERTIARY STRUCTURE DATA | ||||||||
|---|---|---|---|---|---|---|---|---|
| Comment | Resolution | PDB | PDBe | SCOP | CATH | PDBSum | Proteopedia | Reference |
| HIV-1 retropepsin ( human immunodeficiency virus 1) | ||||||||
| Val82Phe, Ile84Val double mutant; complex with tipranavir inhibitor | 2.50 Å | 1D4S | 1D4S | 1D4S | 1D4S | 1D4S | 1D4S | Thaisrivongs et al., 1996 |
| Gln7Lys, Leu33Ile, Leu63Ile mutant: complex with tipranavir | 1.97 Å | 1D4Y | 1D4Y | 1D4Y | 1D4Y | 1D4Y | 1D4Y | Thaisrivongs et al., 1996 |
| Gln7Lys, Ile50Val mutant; complex with Tipranavir | 1.33 Å | 2O4L | 2O4L | 2O4L | 2O4L | 2O4L | 2O4L | Muzammil et al., 2007 |
| TRM mutant; complex with Tipranavir | 2.00 Å | 2O4N | 2O4N | 2O4N | 2O4N | 2O4N | 2O4N | Muzammil et al., 2007 |
| Gln7Lys mutant; complex with Tipranavir | 1.80 Å | 2O4P | 2O4P | 2O4P | 2O4P | 2O4P | 2O4P | Muzammil et al., 2007 |
| multidrug-resistant clinical isolate; complex with tipranavir | 1.80 Å | 4NJU | 4NJU | 4NJU | 4NJU | 4NJU | 4NJU | |
| wild-type hiv-1 protease in complex with tipranavir | 1.20 Å | 6DIF | 6DIF | 6DIF | 6DIF | 6DIF | 6DIF | |
| Leu76Val mutant; complex with tipranavir | 1.48 Å | 6DIL | 6DIL | 6DIL | 6DIL | 6DIL | 6DIL | |
