Structure for bortezomib (T01.010, T01.011, T01.012 inhibitor)
 
| TERTIARY STRUCTURE DATA | ||||||||
|---|---|---|---|---|---|---|---|---|
| Comment | Resolution | PDB | PDBe | SCOP | CATH | PDBSum | Proteopedia | Reference |
| proteasome subunit beta5i ( Homo sapiens) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.50 Å | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | |
| proteasome subunit beta 1 ( Homo sapiens) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.50 Å | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | |
| proteasome subunit beta5c ( Homo sapiens) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.70 Å | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | |
| proteasome subunit beta 1 ( Homo sapiens) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.70 Å | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | |
| proteasome subunit alpha 2 ( Homo sapiens) | ||||||||
| human 20s proteasome complex with bortezomib at 2.1 angstrom ***caveat 5lf3 6v1 u 47 has wrong chirality at atom c1 | 2.10 Å | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | |
| proteasome subunit alpha 4 ( Homo sapiens) | ||||||||
| human 20s proteasome complex with bortezomib at 2.1 angstrom ***caveat 5lf3 6v1 u 47 has wrong chirality at atom c1 | 2.10 Å | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | |
| proteasome subunit alpha 7 ( Homo sapiens) | ||||||||
| human 20s proteasome complex with bortezomib at 2.1 angstrom ***caveat 5lf3 6v1 u 47 has wrong chirality at atom c1 | 2.10 Å | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | |
| proteasome subunit alpha 5 ( Homo sapiens) | ||||||||
| human 20s proteasome complex with bortezomib at 2.1 angstrom ***caveat 5lf3 6v1 u 47 has wrong chirality at atom c1 | 2.10 Å | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | |
| proteasome subunit alpha 1 ( Homo sapiens) | ||||||||
| human 20s proteasome complex with bortezomib at 2.1 angstrom ***caveat 5lf3 6v1 u 47 has wrong chirality at atom c1 | 2.10 Å | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | |
| proteasome subunit alpha 3 ( Homo sapiens) | ||||||||
| human 20s proteasome complex with bortezomib at 2.1 angstrom ***caveat 5lf3 6v1 u 47 has wrong chirality at atom c1 | 2.10 Å | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | |
| proteasome subunit alpha 6 ( Homo sapiens) | ||||||||
| human 20s proteasome complex with bortezomib at 2.1 angstrom ***caveat 5lf3 6v1 u 47 has wrong chirality at atom c1 | 2.10 Å | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | |
| protein serine kinase c17 ( Homo sapiens) | ||||||||
| human 20s proteasome complex with bortezomib at 2.1 angstrom ***caveat 5lf3 6v1 u 47 has wrong chirality at atom c1 | 2.10 Å | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | |
| proteasome subunit beta 3 ( Homo sapiens) | ||||||||
| human 20s proteasome complex with bortezomib at 2.1 angstrom ***caveat 5lf3 6v1 u 47 has wrong chirality at atom c1 | 2.10 Å | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | |
| proteasome subunit beta 2 ( Homo sapiens) | ||||||||
| human 20s proteasome complex with bortezomib at 2.1 angstrom ***caveat 5lf3 6v1 u 47 has wrong chirality at atom c1 | 2.10 Å | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | |
| proteasome subunit beta5c ( Homo sapiens) | ||||||||
| human 20s proteasome complex with bortezomib at 2.1 angstrom ***caveat 5lf3 6v1 u 47 has wrong chirality at atom c1 | 2.10 Å | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | |
| proteasome subunit beta 1 ( Homo sapiens) | ||||||||
| human 20s proteasome complex with bortezomib at 2.1 angstrom ***caveat 5lf3 6v1 u 47 has wrong chirality at atom c1 | 2.10 Å | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | |
| proteasome subunit beta 4 ( Homo sapiens) | ||||||||
| human 20s proteasome complex with bortezomib at 2.1 angstrom ***caveat 5lf3 6v1 u 47 has wrong chirality at atom c1 | 2.10 Å | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | |
| proteasome subunit beta1c ( Homo sapiens) | ||||||||
| human 20s proteasome complex with bortezomib at 2.1 angstrom ***caveat 5lf3 6v1 u 47 has wrong chirality at atom c1 | 2.10 Å | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | |
| proteasome subunit beta5c ( Mus musculus) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with bortezomib | 2.80 Å | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | |
| subfamily T1A unassigned peptidases ( Mus musculus) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with bortezomib | 2.80 Å | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.80 Å | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | Groll et al., 2006 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome;complex with bortezomib | 2.80 Å | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | Groll et al., 2006 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome;complex with bortezomib | 2.80 Å | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | Groll et al., 2006 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome;complex with bortezomib | 2.80 Å | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | Groll et al., 2006 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.80 Å | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | Groll et al., 2006 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome;complex with bortezomib | 2.80 Å | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | Groll et al., 2006 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome;complex with bortezomib | 2.80 Å | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | Groll et al., 2006 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome;complex with bortezomib | 2.80 Å | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | Groll et al., 2006 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome;complex with bortezomib | 2.80 Å | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | Groll et al., 2006 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome;complex with bortezomib | 2.80 Å | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | Groll et al., 2006 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome;complex with bortezomib | 2.80 Å | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | Groll et al., 2006 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome;complex with bortezomib | 2.80 Å | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | Groll et al., 2006 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome;complex with bortezomib | 2.80 Å | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | Groll et al., 2006 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome;complex with bortezomib | 2.80 Å | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | 2F16 | Groll et al., 2006 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.68 Å | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | Blackburn et al., 2010 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.68 Å | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | Blackburn et al., 2010 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.68 Å | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | Blackburn et al., 2010 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.68 Å | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | Blackburn et al., 2010 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.68 Å | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | Blackburn et al., 2010 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.68 Å | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | Blackburn et al., 2010 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.68 Å | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | Blackburn et al., 2010 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.68 Å | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | Blackburn et al., 2010 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.68 Å | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | Blackburn et al., 2010 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.68 Å | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | Blackburn et al., 2010 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.68 Å | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | Blackburn et al., 2010 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.68 Å | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | Blackburn et al., 2010 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.68 Å | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | Blackburn et al., 2010 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.68 Å | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | 3MG0 | Blackburn et al., 2010 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.80 Å | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.80 Å | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.80 Å | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.80 Å | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.80 Å | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.80 Å | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.80 Å | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.80 Å | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.80 Å | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.80 Å | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.80 Å | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.80 Å | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.80 Å | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome; complex with bortezomib | 2.80 Å | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | 4QVL | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with bortezomib | 2.80 Å | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with bortezomib | 2.80 Å | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with bortezomib | 2.80 Å | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with bortezomib | 2.80 Å | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with bortezomib | 2.80 Å | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with bortezomib | 2.80 Å | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with bortezomib | 2.80 Å | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with bortezomib | 2.80 Å | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with bortezomib | 2.80 Å | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with bortezomib | 2.80 Å | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with bortezomib | 2.80 Å | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with bortezomib | 2.80 Å | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with bortezomib | 2.80 Å | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ala mutant; complex with bortezomib | 2.80 Å | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | 4QVM | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with bortezomib | 2.90 Å | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with bortezomib | 2.90 Å | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with bortezomib | 2.90 Å | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with bortezomib | 2.90 Å | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with bortezomib | 2.90 Å | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with bortezomib | 2.90 Å | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with bortezomib | 2.90 Å | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with bortezomib | 2.90 Å | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with bortezomib | 2.90 Å | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with bortezomib | 2.90 Å | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with bortezomib | 2.90 Å | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with bortezomib | 2.90 Å | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with bortezomib | 2.90 Å | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Val mutant; complex with bortezomib | 2.90 Å | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | 4QVN | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with bortezomib | 2.30 Å | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with bortezomib | 2.30 Å | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with bortezomib | 2.30 Å | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with bortezomib | 2.30 Å | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with bortezomib | 2.30 Å | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with bortezomib | 2.30 Å | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with bortezomib | 2.30 Å | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with bortezomib | 2.30 Å | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with bortezomib | 2.30 Å | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with bortezomib | 2.30 Å | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with bortezomib | 2.30 Å | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with bortezomib | 2.30 Å | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with bortezomib | 2.30 Å | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Thr mutant; complex with bortezomib | 2.30 Å | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | 4QVP | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with bortezomib | 2.60 Å | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with bortezomib | 2.60 Å | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with bortezomib | 2.60 Å | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with bortezomib | 2.60 Å | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with bortezomib | 2.60 Å | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with bortezomib | 2.60 Å | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with bortezomib | 2.60 Å | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with bortezomib | 2.60 Å | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with bortezomib | 2.60 Å | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with bortezomib | 2.60 Å | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with bortezomib | 2.60 Å | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with bortezomib | 2.60 Å | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with bortezomib | 2.60 Å | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Met45Ile mutant; complex with bortezomib | 2.60 Å | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | 4QVQ | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with bortezomib | 2.80 Å | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with bortezomib | 2.80 Å | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with bortezomib | 2.80 Å | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with bortezomib | 2.80 Å | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with bortezomib | 2.80 Å | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with bortezomib | 2.80 Å | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with bortezomib | 2.80 Å | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with bortezomib | 2.80 Å | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with bortezomib | 2.80 Å | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with bortezomib | 2.80 Å | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with bortezomib | 2.80 Å | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with bortezomib | 2.80 Å | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with bortezomib | 2.80 Å | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Val mutant; complex with bortezomib | 2.80 Å | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | 4QVV | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with bortezomib | 3.00 Å | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with bortezomib | 3.00 Å | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with bortezomib | 3.00 Å | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with bortezomib | 3.00 Å | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with bortezomib | 3.00 Å | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with bortezomib | 3.00 Å | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with bortezomib | 3.00 Å | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with bortezomib | 3.00 Å | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with bortezomib | 3.00 Å | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with bortezomib | 3.00 Å | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with bortezomib | 3.00 Å | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with bortezomib | 3.00 Å | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with bortezomib | 3.00 Å | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Ser mutant; complex with bortezomib | 3.00 Å | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | 4QVW | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with bortezomib | 2.51 Å | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with bortezomib | 2.51 Å | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with bortezomib | 2.51 Å | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with bortezomib | 2.51 Å | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with bortezomib | 2.51 Å | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with bortezomib | 2.51 Å | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with bortezomib | 2.51 Å | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with bortezomib | 2.51 Å | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with bortezomib | 2.51 Å | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with bortezomib | 2.51 Å | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with bortezomib | 2.51 Å | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with bortezomib | 2.51 Å | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with bortezomib | 2.51 Å | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr mutant; complex with bortezomib | 2.51 Å | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | 4QVY | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr,Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr,Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr,Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr,Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr,Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr,Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr,Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr,Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr,Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr,Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr,Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr,Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr,Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala49Thr,Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | 4QW0 | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Ala50Val mutant; complex with bortezomib | 2.90 Å | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | 4QW1 | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with bortezomib | 2.90 Å | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with bortezomib | 2.90 Å | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with bortezomib | 2.90 Å | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with bortezomib | 2.90 Å | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with bortezomib | 2.90 Å | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with bortezomib | 2.90 Å | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with bortezomib | 2.90 Å | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with bortezomib | 2.90 Å | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with bortezomib | 2.90 Å | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with bortezomib | 2.90 Å | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with bortezomib | 2.90 Å | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with bortezomib | 2.90 Å | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with bortezomib | 2.90 Å | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys63Phe mutant; complex with bortezomib | 2.90 Å | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | 4QW3 | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with bortezomib | 3.00 Å | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | Huber et al., 2015 |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with bortezomib | 3.00 Å | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with bortezomib | 3.00 Å | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with bortezomib | 3.00 Å | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | Huber et al., 2015 |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with bortezomib | 3.00 Å | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | Huber et al., 2015 |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with bortezomib | 3.00 Å | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | Huber et al., 2015 |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with bortezomib | 3.00 Å | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | Huber et al., 2015 |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with bortezomib | 3.00 Å | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | Huber et al., 2015 |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with bortezomib | 3.00 Å | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | Huber et al., 2015 |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with bortezomib | 3.00 Å | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | Huber et al., 2015 |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with bortezomib | 3.00 Å | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | Huber et al., 2015 |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with bortezomib | 3.00 Å | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | Huber et al., 2015 |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with bortezomib | 3.00 Å | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | Huber et al., 2015 |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| 20S proteasome beta5 Cys52Phe mutant; complex with bortezomib | 3.00 Å | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | 4QWU | Huber et al., 2015 |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g170a mutant in complex with bortezomib | 2.80 Å | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g170a mutant in complex with bortezomib | 2.80 Å | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g170a mutant in complex with bortezomib | 2.80 Å | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g170a mutant in complex with bortezomib | 2.80 Å | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g170a mutant in complex with bortezomib | 2.80 Å | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g170a mutant in complex with bortezomib | 2.80 Å | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g170a mutant in complex with bortezomib | 2.80 Å | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g170a mutant in complex with bortezomib | 2.80 Å | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g170a mutant in complex with bortezomib | 2.80 Å | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g170a mutant in complex with bortezomib | 2.80 Å | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g170a mutant in complex with bortezomib | 2.80 Å | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g170a mutant in complex with bortezomib | 2.80 Å | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g170a mutant in complex with bortezomib | 2.80 Å | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g170a mutant in complex with bortezomib | 2.80 Å | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | 5BXN | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1a beta5-k81r double mutant in complex with bortezomib, propeptide expressed in cis | 2.50 Å | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1a beta5-k81r double mutant in complex with bortezomib, propeptide expressed in cis | 2.50 Å | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1a beta5-k81r double mutant in complex with bortezomib, propeptide expressed in cis | 2.50 Å | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1a beta5-k81r double mutant in complex with bortezomib, propeptide expressed in cis | 2.50 Å | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1a beta5-k81r double mutant in complex with bortezomib, propeptide expressed in cis | 2.50 Å | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1a beta5-k81r double mutant in complex with bortezomib, propeptide expressed in cis | 2.50 Å | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1a beta5-k81r double mutant in complex with bortezomib, propeptide expressed in cis | 2.50 Å | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1a beta5-k81r double mutant in complex with bortezomib, propeptide expressed in cis | 2.50 Å | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1a beta5-k81r double mutant in complex with bortezomib, propeptide expressed in cis | 2.50 Å | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1a beta5-k81r double mutant in complex with bortezomib, propeptide expressed in cis | 2.50 Å | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1a beta5-k81r double mutant in complex with bortezomib, propeptide expressed in cis | 2.50 Å | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1a beta5-k81r double mutant in complex with bortezomib, propeptide expressed in cis | 2.50 Å | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1a beta5-k81r double mutant in complex with bortezomib, propeptide expressed in cis | 2.50 Å | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1a beta5-k81r double mutant in complex with bortezomib, propeptide expressed in cis | 2.50 Å | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | 5CZ7 | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with bortezomib | 2.60 Å | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with bortezomib | 2.60 Å | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with bortezomib | 2.60 Å | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with bortezomib | 2.60 Å | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with bortezomib | 2.60 Å | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with bortezomib | 2.60 Å | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with bortezomib | 2.60 Å | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with bortezomib | 2.60 Å | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with bortezomib | 2.60 Å | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with bortezomib | 2.60 Å | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with bortezomib | 2.60 Å | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with bortezomib | 2.60 Å | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with bortezomib | 2.60 Å | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta5-t1s mutant in complex with bortezomib | 2.60 Å | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | 5D0X | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.50 Å | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.50 Å | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.50 Å | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.50 Å | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.50 Å | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.50 Å | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.50 Å | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.50 Å | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.50 Å | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.50 Å | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.50 Å | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.50 Å | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.50 Å | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.50 Å | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | 5L5F | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.70 Å | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.70 Å | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.70 Å | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.70 Å | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.70 Å | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.70 Å | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.70 Å | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.70 Å | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.70 Å | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.70 Å | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.70 Å | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.70 Å | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.70 Å | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib | 2.70 Å | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | 5L5Z | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with bortezomib | 2.80 Å | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with bortezomib | 2.80 Å | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with bortezomib | 2.80 Å | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with bortezomib | 2.80 Å | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with bortezomib | 2.80 Å | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with bortezomib | 2.80 Å | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with bortezomib | 2.80 Å | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with bortezomib | 2.80 Å | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with bortezomib | 2.80 Å | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with bortezomib | 2.80 Å | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with bortezomib | 2.80 Å | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with bortezomib | 2.80 Å | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with bortezomib | 2.80 Å | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with bortezomib | 2.80 Å | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | 5L66 | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with bortezomib | 2.80 Å | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | |
| proteasome subunit alpha 4 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with bortezomib | 2.80 Å | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with bortezomib | 2.80 Å | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | |
| subfamily T1A unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with bortezomib | 2.80 Å | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | |
| proteasome subunit alpha 1 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with bortezomib | 2.80 Å | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | |
| family T1 unassigned peptidases ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with bortezomib | 2.80 Å | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | |
| proteasome subunit alpha 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with bortezomib | 2.80 Å | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | |
| proteasome subunit beta2c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with bortezomib | 2.80 Å | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | |
| subfamily T1A non-peptidase homologues ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with bortezomib | 2.80 Å | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | |
| proteasome subunit beta 2 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with bortezomib | 2.80 Å | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | |
| proteasome subunit beta5c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with bortezomib | 2.80 Å | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | |
| 20S proteasome component beta 6 ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with bortezomib | 2.80 Å | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | |
| psmB4-2 g.p. (Dictyostelium discoideum) ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with bortezomib | 2.80 Å | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | |
| proteasome subunit beta1c ( Saccharomyces cerevisiae) | ||||||||
| yeast 20s proteasome beta2-g45a mutant in complex with bortezomib | 2.80 Å | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | 6HWD | |
