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Literature for bortezomib (T01.010, T01.011, T01.012 inhibitor)

Summary Structure Literature Inhibits

(Topics flags: S Structure, T Target, K Knockout, P Specificity, V Review, M Mutation, I Inhibitor, L Localization. To select only the references relevant to a single topic, click the link above. See explanation.)

    2020
  1. Vora,P.A., Patel,R. and Dharamsi,A.
    Bortezomib - first therapeutic proteasome inhibitor for cancer therapy: a review of patent literature
    Recent Pat Anticancer Drug Discov (2020) 15, 113-131. PubMed  Europe PubMed DOI  V  I
    2. 2019
  2. Besse,A., Besse,L., Kraus,M., Mendez-Lopez,M., Bader,J., Xin,B.T., de Bruin,G., Maurits,E., Overkleeft,H.S. and Driessen,C.
    Proteasome Inhibition in Multiple Myeloma: Head-to-Head Comparison of Currently Available Proteasome Inhibitors
    Cell Chem Biol (2019) 26, 340-351. PubMed  Europe PubMed DOI  I
  3. Dang,Q., Chen,L., Xu,M., You,X., Zhou,H., Zhang,Y. and Shi,W.
    The gamma-secretase inhibitor GSI-I interacts synergistically with the proteasome inhibitor bortezomib to induce ALK+ anaplastic large cell lymphoma cell apoptosis
    Cell Signal (2019) 59, 76-84. PubMed  Europe PubMed DOI  I
  4. Felix,J., Weinhaupl,K., Chipot,C., Dehez,F., Hessel,A., Gauto,D.F., Morlot,C., Abian,O., Gutsche,I., Velazquez-Campoy,A., Schanda,P. and Fraga,H.
    Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors
    Sci Adv (2019) 5, eaaw3818-eaaw3818. PubMed  Europe PubMed DOI  PMC  EPMC  I
  5. Kuroda,K. and Liu,H.
    The proteasome inhibitor, bortezomib, induces prostate cancer cell death by suppressing the expression of prostate-specific membrane antigen, as well as androgen receptor
    Int J Oncol (2019) 54, 1357-1366. PubMed  Europe PubMed DOI  I
  6. Lee,M.J., Bhattarai,D., Yoo,J., Miller,Z., Park,J.E., Lee,S., Lee,W., Driscoll,J.J. and Kim,K.B.
    Development of novel epoxyketone-based proteasome inhibitors as a strategy to overcome cancer resistance to carfilzomib and bortezomib
    J Med Chem (2019) 62, 4444-4455. PubMed  Europe PubMed DOI  I
  7. Liu,S., Liu,H., Zhang,K., Li,X., Duan,Y., Wang,Z. and Wang,T.
    Proteasome inhibitor PS-341 effectively blocks infection by the Severe Fever with Thrombocytopenia Syndrome virus
    Virol Sin (2019) 34, 572-582. PubMed  Europe PubMed DOI  I
    8. 2018
  8. Xu,Y., Yang,X., Chen,Y., Chen,H., Sun,H., Li,W., Xie,Q., Yu,L. and Shao,L.
    Discovery of novel 20S proteasome inhibitors by rational topology-based scaffold hopping of bortezomib
    Bioorg Med Chem Lett (2018) 28, 2148-2152. PubMed  Europe PubMed DOI  I
    9. 2017
  9. Moreira,W., Santhanakrishnan,S., Ngan,G.J., Low,C.B., Sangthongpitag,K., Poulsen,A., Dymock,B.W. and Dick,T.
    Towards selective mycobacterial ClpP1P2 inhibitors with reduced activity against the human proteasome
    Antimicrob Agents Chemother (2017) 61, e02307-16-e02307-16. PubMed  Europe PubMed DOI  I
  10. Moreira,W., Santhanakrishnan,S., Dymock,B.W. and Dick,T.
    Bortezomib warhead-switch confers dual activity against mycobacterial caseinolytic protease and proteasome and selectivity against human proteasome
    Front Microbiol (2017) 8, 746-746. PubMed  Europe PubMed DOI  PMC  EPMC  I
  11. Weyburne,E.S., Wilkins,O.M., Sha,Z., Williams,D.A., Pletnev,A.A., de Bruin,G., Overkleeft,H.S., Goldberg,A.L., Cole,M.D. and Kisselev,A.F.
    Inhibition of the proteasome beta2 site sensitizes triple-negative breast cancer cells to beta5 inhibitors and suppresses Nrf1 activation
    Cell Chem Biol (2017) 24, 218-230. PubMed  Europe PubMed DOI  T  I
    12. 2016
  12. Csizmadia,V., Hales,P., Tsu,C., Ma,J., Chen,J., Shah,P., Fleming,P., Senn,J.J., Kadambi,V.J., Dick,L. and Wolenski,F.S.
    Proteasome inhibitors bortezomib and carfilzomib used for the treatment of multiple myeloma do not inhibit the serine protease HtrA2/Omi
    Toxicol Res (2016) 5, 1619-1628. DOI  I
  13. de Bruin,G., Mock,E.D., Hoogendoorn,S., van den Nieuwendijk,A.M., Mazurek,J., van der Marel,G.A., Florea,B.I. and Overkleeft,H.S.
    Enantioselective synthesis of adamantylalanine and carboranylalanine and their incorporation into the proteasome inhibitor bortezomib
    Chem Commun (Camb) (2016) 52, 4064-4067. PubMed  Europe PubMed DOI  I
  14. Tew,K.D.
    Commentary on "Proteasome inhibitors: a novel class of potent and effective antitumor agents"
    Cancer Res (2016) 76, 4916-4917. PubMed  Europe PubMed DOI  I
  15. Toscani,D., Palumbo,C., Dalla Palma,B., Ferretti,M., Bolzoni,M., Marchica,V., Sena,P., Martella,E., Mancini,C., Ferri,V., Costa,F., Accardi,F., Craviotto,L., Aversa,F. and Giuliani,N.
    The proteasome inhibitor bortezomib maintains osteocyte viability in multiple myeloma patients by reducing both apoptosis and autophagy: a new function for proteasome inhibitors
    J Bone Miner Res (2016) 31, 815-827. PubMed  Europe PubMed DOI  I
  16. Wu,Y.X., Yang,J.H. and Saitsu,H.
    Bortezomib-resistance is associated with increased levels of proteasome subunits and apoptosis-avoidance
    Oncotarget (2016) 7, 77622-77634. PubMed  Europe PubMed DOI  I
  17. Zhang,Y., Cheng,J., Zhang,J., Wu,X., Chen,F., Ren,X., Wang,Y., Li,Q. and Li,Y.
    Proteasome inhibitor PS-341 limits macrophage necroptosis by promoting cIAPs-mediated inhibition of RIP1 and RIP3 activation
    Biochem Biophys Res Commun (2016) 477, 761-767. PubMed  Europe PubMed DOI  I
    18. 2015
  18. Amaya,M., Keck,F., Lindquist,M., Voss,K., Scavone,L., Kehn-Hall,K., Roberts,B., Bailey,C., Schmaljohn,C. and Narayanan,A.
    The ubiquitin proteasome system plays a role in Venezuelan equine encephalitis virus infection
    PLoS ONE (2015) 10, e0124792- PubMed  Europe PubMed DOI  PMC  EPMC  I
  19. Dolloff,N.G.
    Emerging therapeutic strategies for overcoming proteasome inhibitor resistance
    Adv Cancer Res (2015) 127, 191-226. PubMed  Europe PubMed DOI  I
  20. Glynn,S.J., Gaffney,K.J., Sainz,M.A., Louie,S.G. and Petasis,N.A.
    Molecular characterization of the boron adducts of the proteasome inhibitor bortezomib with epigallocatechin-3-gallate and related polyphenols
    Org Biomol Chem (2015) 13, 3887-3899. PubMed  Europe PubMed DOI  I
  21. Huber,E.M., Heinemeyer,W. and Groll,M.
    Bortezomib-resistant mutant proteasomes: structural and biochemical evaluation with carfilzomib and ONX 0914
    Structure (2015) 23, 407-417. PubMed  Europe PubMed DOI  S  I
  22. Moreira,W., Ngan,G.J., Low,J.L., Poulsen,A., Chia,B.C., Ang,M.J., Yap,A., Fulwood,J., Lakshmanan,U., Lim,J., Khoo,A.Y., Flotow,H., Hill,J., Raju,R.M., Rubin,E.J. and Dick,T.
    Target mechanism-based whole-cell screening identifies bortezomib as an inhibitor of caseinolytic protease in mycobacteria
    MBio (2015) 6, e00253-e00215. PubMed  Europe PubMed DOI  I
  23. Niewerth,D., Jansen,G., Assaraf,Y.G., Zweegman,S., Kaspers,G.J. and Cloos,J.
    Molecular basis of resistance to proteasome inhibitors in hematological malignancies
    Drug Resist Updat (2015) 18, 18-35. PubMed  Europe PubMed DOI  V  I
  24. Roelofs,J.
    Proteasome inhibition by bortezomib: a left hook and a right punch
    EBioMedicine (2015) 2, 619-620. PubMed  Europe PubMed DOI  PMC  EPMC  I
  25. Teicher,B.A. and Tomaszewski,J.E.
    Proteasome Inhibitors
    Biochem Pharmacol (2015) 96, 1-9. PubMed  Europe PubMed DOI  I
    26. 2014
  26. Coelho,S.C., Rocha,S., Pereira,M.C., Juzenas,P. and Coelho,M.A.
    Enhancing proteasome-lnhibitor effect by functionalized gold nanoparticles
    J Biomed Nanotechnol (2014) 10, 717-723. PubMed  Europe PubMed DOI  I
  27. Dasgupta,S., Castro,L.M., Dulman,R., Yang,C., Schmidt,M., Ferro,E.S. and Fricker,L.D.
    Proteasome inhibitors alter levels of intracellular peptides in HEK293T and SH-SY5Y cells
    PLoS ONE (2014) 9, e103604-e103604. PubMed  Europe PubMed DOI  PMC  EPMC  I
  28. Dou,Q.P. and Zonder,J.A.
    Overview of proteasome inhibitor-based anti-cancer therapies: Perspective on Bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome system
    Curr Cancer Drug Targets (2014) 14, 517-536. PubMed  Europe PubMed DOI  I
  29. Niewerth,D., Kaspers,G.J., Assaraf,Y.G., van Meerloo,J., Kirk,C.J., Anderl,J., Blank,J.L., van de Ven,P.M., Zweegman,S., Jansen,G. and Cloos,J.
    Interferon-gamma-induced upregulation of immunoproteasome subunit assembly overcomes bortezomib resistance in human hematological cell lines
    J Hematol Oncol (2014) 7, 7-7. PubMed  Europe PubMed DOI  I
  30. Stadelmann,B., Aeschbacher,D., Huber,C., Spiliotis,M., Muller,J. and Hemphill,A.
    Profound activity of the anti-cancer drug bortezomib against Echinococcus multilocularis metacestodes identifies the proteasome as a novel drug target for cestodes
    PLoS Negl Trop Dis (2014) 8, e3352-e3352. PubMed  Europe PubMed DOI  I
  31. Wang,Y.Y., Luan,Y., Zhang,X., Lin,M., Zhang,Z.H., Zhu,X.B., Ma,Y. and Wang,Y.B.
    Proteasome inhibitor PS-341 attenuates flow-induced pulmonary arterial hypertension
    Clin Exp Med (2014) 14, 321-329. PubMed  Europe PubMed DOI  I
  32. Yucel,G., Van Arnam,J., Means,P.C., Huntzicker,E., Altindag,B., Lara,M.F., Yuan,J., Kuo,C. and Oro,A.E.
    Partial proteasome inhibitors induce hair follicle growth by stabilizing beta-catenin
    Stem Cells (2014) 32, 85-92. PubMed  Europe PubMed DOI  I
    33. 2013
  33. Agyin,J.K., Santhamma,B. and Roy,S.S.
    Design, synthesis, and biological evaluation of bone-targeted proteasome inhibitors for multiple myeloma
    Bioorg Med Chem Lett (2013) 23, 6455-6458. PubMed  Europe PubMed DOI  I
  34. Araujo,K.P., Bonuccelli,G., Duarte,C.N., Gaiad,T.P., Moreira,D.F., Feder,D., Belizario,J.E., Miglino,M.A., Lisanti,M.P. and Ambrosio,C.E.
    Bortezomib (PS-341) treatment decreases inflammation and partially rescues the expression of the dystrophin-glycoprotein complex in GRMD dogs
    PLoS ONE (2013) 8, e61367-e61367. PubMed  Europe PubMed DOI  PMC  EPMC  I
  35. Cao,B., Li,J. and Mao,X.
    Dissecting bortezomib: development, application, adverse effects and future direction
    Curr Pharm Des (2013) 19, 3190-3200. PubMed  Europe PubMed  V  I
  36. Chen,F.T., Yang,C.M. and Yang,C.H.
    The protective effects of the proteasome inhibitor bortezomib (velcade) on ischemia-reperfusion injury in the rat retina
    PLoS ONE (2013) 8, e64262-e64262. PubMed  Europe PubMed DOI  PMC  EPMC  I
  37. Dimopoulos,M.A., Terpos,E. and Kastritis,E.
    Proteasome inhibitor therapy for Waldenstrom's macroglobulinemia
    Clin Lymphoma Myeloma Leuk (2013) 13, 235-237. PubMed  Europe PubMed DOI  I
  38. Escalante,A.M., McGrath,R.T., Karolak,M.R., Dorr,R.T., Lynch,R.M. and Landowski,T.H.
    Preventing the autophagic survival response by inhibition of calpain enhances the cytotoxic activity of bortezomib in vitro and in vivo
    Cancer Chemother Pharmacol (2013) 71, 1567-1576. PubMed  Europe PubMed DOI  I
  39. Ito,K., Kobayashi,M., Kuroki,S., Sasaki,Y., Iwata,T., Mori,K., Kuroki,T., Ozawa,Y., Tetsuka,M., Nakagawa,T., Hiroi,T., Yamamoto,H., Ono,K., Washizu,T. and Bonkobara,M.
    The proteasome inhibitor bortezomib inhibits the growth of canine malignant melanoma cells in vitro and in vivo
    Vet J (2013) 198, 577-582. PubMed  Europe PubMed DOI  I
  40. Leung-Hagesteijn,C., Erdmann,N., Cheung,G., Keats,J.J., Stewart,A.K., Reece,D.E., Chung,K.C. and Tiedemann,R.E.
    Xbp1s-negative tumor B cells and pre-plasmablasts mediate therapeutic proteasome inhibitor resistance in multiple myeloma
    Cancer Cell (2013) 24, 289-304. PubMed  Europe PubMed DOI  I
  41. Li,A.C., Yu,E., Ring,S.C. and Chovan,J.P.
    Boronic acid-containing proteasome inhibitors: alert to potential pharmaceutical bioactivation
    Chem Res Toxicol (2013) 26, 608-615. PubMed  Europe PubMed DOI  I
  42. Lu,S. and Wang,J.
    The resistance mechanisms of proteasome inhibitor bortezomib
    Biomark Res (2013) 1, 13-13. PubMed  Europe PubMed DOI  I
  43. Matteson,D.S.
    Boronic esters in asymmetric synthesis
    J Org Chem (2013) 78, 10009-10023. PubMed  Europe PubMed DOI  I
  44. Orlowski,R.Z.
    Why Proteasome Inhibitors Cannot ERADicate Multiple Myeloma
    Cancer Cell (2013) 24, 275-277. PubMed  Europe PubMed DOI  I
  45. Sridhar,S., Bhat,G. and Guruprasad,K.
    Analysis of bortezomib inhibitor docked within the catalytic subunits of the Plasmodium falciparum 20S proteasome
    SpringerPlus (2013) 2, 566-566. PubMed  Europe PubMed DOI  PMC  EPMC  I
  46. Velentzas,P.D., Velentzas,A.D., Mpakou,V.E., Antonelou,M.H., Margaritis,L.H., Papassideri,I.S. and Stravopodis,D.J.
    Detrimental effects of proteasome inhibition activity in Drosophila melanogaster: implication of ER stress, autophagy, and apoptosis
    Cell Biol Toxicol (2013) 29, 13-37. PubMed  Europe PubMed DOI  I
  47. Zaouali,M.A., Bardag-Gorce,F., Carbonell,T., Oliva,J., Pantazi,E., Bejaoui,M., Abdennebi,H.B., Rimola,A. and Rosello-Catafau,J.
    Proteasome inhibitors protect the steatotic and non-steatotic liver graft against cold ischemia reperfusion injury
    Exp Mol Pathol (2013) 94, 352-359. PubMed  Europe PubMed DOI  I
    48. 2012
  48. Altmann,A., Markert,A., Askoxylakis,V., Schoning,T., Jesenofsky,R., Eisenhut,M. and Haberkorn,U.
    Antitumor effects of proteasome inhibition in anaplastic thyroid carcinoma
    J Nucl Med (2012) 53, 1764-1771. PubMed  Europe PubMed DOI  I
  49. Berkers,C.R., Leestemaker,Y., Schuurman,K.G., Ruggeri,B., Jones-Bolin,S., Williams,M. and Ovaa,H.
    Probing the specificity and activity profiles of the proteasome inhibitors bortezomib and delanzomib
    Mol Pharm (2012) 9, 1126-1135. PubMed  Europe PubMed DOI  I
  50. Caballero-Velazquez,T., Sanchez-Abarca,L.I., Gutierrez-Cosio,S., Blanco,B., Calderon,C., Herrero,C., Carrancio,S., Serrano,C., Del Canizo,C., San Miguel,J.F. and Perez-Simon,J.A.
    The novel combination of sirolimus and bortezomib prevents graft-versus-host disease but maintains the graft-versus-leukemia effect after allogeneic transplantation
    Haematologica (2012) 97, 1329-1337. PubMed  Europe PubMed DOI  I
  51. de Wilt,L.H., Jansen,G., Assaraf,Y.G., van Meerloo,J., Cloos,J., Schimmer,A.D., Chan,E.T., Kirk,C.J., Peters,G.J. and Kruyt,F.A.
    Proteasome-based mechanisms of intrinsic and acquired bortezomib resistance in non-small cell lung cancer
    Biochem Pharmacol (2012) 83, 207-217. PubMed  Europe PubMed DOI  I
  52. Eriksson,E., Zaman,F., Chrysis,D., Wehtje,H., Heino,T.J. and Savendahl,L.
    Bortezomib is cytotoxic to the human growth plate and permanently impairs bone growth in young mice
    PLoS ONE (2012) 7, e50523-e50523. PubMed  Europe PubMed DOI  PMC  EPMC  I
  53. Esseltine,D.L. and Mulligan,G.
    An historic perspective of proteasome inhibition
    Semin Hematol (2012) 49, 196-206. PubMed  Europe PubMed DOI  V  I
  54. Everly,M.J., Terasaki,P.I. and Trivedi,H.L.
    Durability of antibody removal following proteasome inhibitor-based therapy
    Transplantation (2012) 93, 572-577. PubMed  Europe PubMed DOI  I
  55. Fang,H.T., Zhang,B., Pan,X.F., Gao,L., Zhen,T., Zhao,H.X., Ma,L., Xie,J., Liu,Z., Yu,X.J., Cheng,X., Feng,T.T., Zhang,F.X., Yang,Y., Hu,Z.G., Sheng,G.Q., Chen,Y.L., Chen,S.J., Chen,Z. and Zhou,G.B.
    Bortezomib interferes with C-KIT processing and transforms the t(8;21)-generated fusion proteins into tumor-suppressing fragments in leukemia cells
    Proc Natl Acad Sci U S A (2012) 109, 2521-2526. PubMed  Europe PubMed DOI  I
  56. Franke,N.E., Niewerth,D., Assaraf,Y.G., van Meerloo,J., Vojtekova,K., van Zantwijk,C.H., Zweegman,S., Chan,E.T., Kirk,C.J., Geerke,D.P., Schimmer,A.D., Kaspers,G.J., Jansen,G. and Cloos,J.
    Impaired bortezomib binding to mutant beta5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells
    Leukemia (2012) 26, 757-768. PubMed  Europe PubMed DOI  M  I
  57. Gu,J.L., Li,J., Zhou,Z.H., Liu,J.R., Huang,B.H., Zheng,D. and Su,C.
    Differentiation induction enhances bortezomib efficacy and overcomes drug resistance in multiple myeloma
    Biochem Biophys Res Commun (2012) 420, 644-650. PubMed  Europe PubMed DOI  I
  58. Huang,C., Hu,X., Wang,L., Lu,S., Cheng,H., Song,X., Wang,J. and Yang,J.
    Bortezomib suppresses the growth of leukemia cells with Notch1 overexpression in vivo and in vitro
    Cancer Chemother Pharmacol (2012) 70, 801-809. PubMed  Europe PubMed DOI  I
  59. Kale,A.J. and Moore,B.S.
    Molecular mechanisms of acquired proteasome inhibitor resistance
    J Med Chem (2012) 55, 10317-10327. PubMed  Europe PubMed DOI  I
  60. Khan,T.M., Benaich,N., Malone,C.F., Bernardos,R.L., Russell,A.R., Downes,G.B., Barresi,M.J. and Hutson,L.D.
    Vincristine and bortezomib cause axon outgrowth and behavioral defects in larval zebrafish
    J Peripher Nerv Syst (2012) 17, 76-89. PubMed  Europe PubMed DOI  I
  61. Mao,X., Pan,X., Cheng,T. and Zhang,X.
    Therapeutic potential of the proteasome inhibitor bortezomib on titanium particle-induced inflammation in a murine model
    Inflammation (2012) 35, 905-912. PubMed  Europe PubMed DOI  I
  62. Mao,X., Pan,X., Zhao,S., Peng,X., Cheng,T. and Zhang,X.
    Protection against titanium particle-induced inflammatory osteolysis by the proteasome inhibitor bortezomib in vivo
    Inflammation (2012) 35, 1378-1391. PubMed  Europe PubMed DOI  I
  63. Momose,I., Tatsuda,D., Ohba,S., Masuda,T., Ikeda,D. and Nomoto,A.
    In vivo imaging of proteasome inhibition using a proteasome-sensitive fluorescent reporter
    Cancer Sci (2012) 103, 1730-1736. PubMed  Europe PubMed DOI  L  I
  64. Nishihori,T., Alekshun,T.J., Shain,K., Sullivan,D.M., Baz,R., Perez,L., Pidala,J., Kharfan-Dabaja,M.A., Ochoa-Bayona,J.L., Fernandez,H.F., Yarde,D.N., Oliveira,V., Fulp,W., Han,G., Kim,J., Chen,D.T., Raychaudhuri,J., Dalton,W., Anasetti,C. and Alsina,M.
    Bortezomib salvage followed by a phase I/II study of bortezomib plus high-dose melphalan and tandem autologous transplantation for patients with primary resistant myeloma
    Br J Haematol (2012) 157, 553-563. PubMed  Europe PubMed DOI  I
  65. Padrissa-Altes,S., Zaouali,M.A., Boncompagni,E., Bonaccorsi-Riani,E., Carbonell,T., Bardag-Gorce,F., Oliva,J., French,S.W., Bartrons,R. and Rosello-Catafau,J.
    The use of a reversible proteasome inhibitor in a model of reduced-size orthotopic liver transplantation in rats
    Exp Mol Pathol (2012) 93, 99-110. PubMed  Europe PubMed DOI  I
  66. Paterno,F., Shiller,M., Tillery,G., O'Leary,J.G., Susskind,B., Trotter,J. and Klintmalm,G.B.
    Bortezomib for acute antibody-mediated rejection in liver transplantation
    Am J Transplant (2012) 12, 2526-2531. PubMed  Europe PubMed DOI  I
  67. Sato,A., Asano,T., Ito,K. and Asano,T.
    Ritonavir interacts with bortezomib to enhance protein ubiquitination and histone acetylation synergistically in renal cancer cells
    Urology (2012) 79, 966-921. PubMed  Europe PubMed DOI  I
  68. Sureshkumar,K.K., Hussain,S.M., Marcus,R.J., Ko,T.Y., Khan,A.S., Tom,K., Vivas,C.A., Parris,G., Jasnosz,K.M. and Thai,N.L.
    Proteasome inhibition with bortezomib: an effective therapy for severe antibody mediated rejection after renal transplantation
    Clin Nephrol (2012) 77, 246-253. PubMed  Europe PubMed  I
  69. Wunderlich,A., Arndt,T., Fischer,M., Roth,S., Ramaswamy,A., Greene,B.H., Brendel,C., Hinterseher,U., Bartsch,D.K. and Hoffmann,S.
    Targeting the proteasome as a promising therapeutic strategy in thyroid cancer
    J Surg Oncol (2012) 105, 357-364. PubMed  Europe PubMed DOI  I
  70. Zeng,Z., Zheng,L., Lin,J. and Chen,J.
    Successful bortezomib treatment in combination with dexamethasone and thalidomide for previously untreated epidural plasmacytoma
    Oncol Lett (2012) 3, 557-559. PubMed  Europe PubMed DOI  PMC  EPMC  I
  71. Zhang,L., Teng,Y., Zhang,Y., Liu,J., Xu,L., Qu,J., Hou,K., Liu,Y. and Qu,X.
    Proteasome inhibitor bortezomib (PS-341) enhances RANKL-induced MDA-MB-231 breast cancer cell migration
    Mol Med Rep (2012) 5, 580-584. PubMed  Europe PubMed DOI  I
    72. 2011
  72. Arastu-Kapur,S., Anderl,J.L., Kraus,M., Parlati,F., Shenk,K.D., Lee,S.J., Muchamuel,T., Bennett,M.K., Driessen,C., Ball,A.J. and Kirk,C.J.
    Nonproteasomal targets of the proteasome inhibitors bortezomib and carfilzomib: a link to clinical adverse events
    Clin Cancer Res (2011) 17, 2734-2743. PubMed  Europe PubMed DOI  I
  73. Bardag-Gorce,F.
    Proteasome inhibitor treatment in alcoholic liver disease
    World J Gastroenterol (2011) 17, 2558-2562. PubMed  Europe PubMed DOI  PMC  EPMC  I
  74. Blanco,B., Sanchez-Abarca,L.I., Caballero-Velazquez,T., Santamaria,C., Inoges,S. and Perez-Simon,J.A.
    Depletion of alloreactive T-cells in vitro using the proteasome inhibitor bortezomib preserves the immune response against pathogens
    Leuk Res (2011) 35, 1412-1415. PubMed  Europe PubMed DOI  I
  75. Chen,D., Frezza,M., Schmitt,S., Kanwar,J. and Dou,Q.P.
    Bortezomib as the first proteasome inhibitor anticancer drug: current status and future perspectives
    Curr Cancer Drug Targets (2011) 11, 239-253. PubMed  Europe PubMed DOI  I
  76. Chen,F., Pisklakova,A., Li,M., Baz,R., Sullivan,D.M. and Nefedova,Y.
    Gamma-secretase inhibitor enhances the cytotoxic effect of bortezomib in multiple myeloma
    Cell Oncol (Dordr) (2011) 34, 545-551. PubMed  Europe PubMed DOI  I
  77. Cvek,B. and Dvorak,Z.
    The ubiquitin-proteasome system (UPS) and the mechanism of action of bortezomib
    Curr Pharm Des (2011) 17, 1483-1499. PubMed  Europe PubMed DOI  I
  78. Escobar,M., Velez,M., Belalcazar,A., Santos,E.S. and Raez,L.E.
    The role of proteasome inhibition in nonsmall cell lung cancer
    J Biomed Biotechnol (2011) 2011, 806506-806506. PubMed  Europe PubMed DOI  PMC  EPMC  V  I
  79. Gryder,B.E., Guerrant,W., Chen,C.H. and Oyelere,A.K.
    Oxathiazole-2-one derivative of bortezomib: synthesis, stability and proteasome inhibition activity
    MedChemComm (2011) 2, 1083-1086. DOI  I
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