Structure for fumagillin (M24.002 inhibitor)

Summary Structure Literature

 

TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
subfamily M24A unassigned peptidases ( Encephalitozoon cuniculi)
complex with angiogenesis inhibitor fumagillan 2.50 Å 3FMQ 3FMQ 3FMQ 3FMQ 3FMQ 3FMQ Alvarado et al., 2009
methionyl aminopeptidase 2 ( Homo sapiens)
complex with fumagillin inhibitor 1.80 Å 1BOA 1BOA 1BOA 1BOA 1BOA 1BOA Liu et al., 1998
methionyl aminopeptidase 1 (eukaryote) ( Homo sapiens)
Phe309Met mutant; complex with ovalicin 1.68 Å 5YKP 5YKP 5YKP 5YKP 5YKP 5YKP
Phe309Leu mutant; complex with ovalicin 1.60 Å 5YR5 5YR5 5YR5 5YR5 5YR5 5YR5