Structure for Ep475 (C01.001 inhibitor)

Summary Structure Literature

 

PDB Organism Resolution Comment
1PE6 Carica papaya 2.10 Å complex with E64C
Catalytic residues are shown in ball-and-stick representation: Cys158 in yellow, His292 in purple and Asn308 in pink. E-64 is shown in grey in ball-and-stick representation.
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TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
actinidin ( Actinidia deliciosa)
theoretical model; complex with E64c 0.00 Å 1FTV 1FTV 1FTV 1FTV 1FTV 1FTV
cathepsin B ( Bos taurus)
complex with E64c 2.29 Å 1ITO 1ITO 1ITO 1ITO 1ITO 1ITO Yamamoto et al., 2002
caricain ( Carica papaya)
theoretical model; Asp158Glu mutant in complex with E64c 0.00 Å 1EUX 1EUX 1EUX 1EUX 1EUX 1EUX
cathepsin H propeptide ( Carica papaya)
theoretical model; Asp158Glu mutant in complex with E64c 0.00 Å 1EUX 1EUX 1EUX 1EUX 1EUX 1EUX
papain ( Carica papaya)
complex with E64C 2.10 Å 1PE6 1PE6 1PE6 1PE6 1PE6 1PE6 Yamamoto et al., 1991
complex with E64C 1.90 Å 1PPP 1PPP 1PPP 1PPP 1PPP 1PPP Kim et al., 1992