Structure for inhibitor I32.004: XIAP caspase inhibitor

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Pharma

 

PDB Organism Resolution Comment
1NW9_A Homo sapiens 2.40 Å complex with caspase-9
The inhibitor (XIAP) is shown in colour ribbon representation. The structural zinc atom is shown as a light grey CPK sphere.
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TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
Homo sapiens
NMR structure 0.00 Å 1C9Q 1C9Q 1C9Q 1C9Q 1C9Q 1C9Q Sun et al., 1999
NMR structure 0.00 Å 1F9X 1F9X 1F9X 1F9X 1F9X 1F9X Sun et al., 2000
NMR structure; complex with nonapeptide from SmaC/Diablo 0.00 Å 1G3F 1G3F 1G3F 1G3F 1G3F 1G3F Liu et al., 2000
complex with SmaC 2.00 Å 1G73 1G73 1G73 1G73 1G73 1G73 Wu et al., 2000
complex with caspase 3 2.70 Å 1I3O 1I3O 1I3O 1I3O 1I3O 1I3O Riedl et al., 2001
complex with caspase-7 2.45 Å 1I51 1I51 1I51 1I51 1I51 1I51 Chai et al., 2001
CRYSTAL STRUCTURE OF THE CASPASE-7 / XIAP-BIR2 COMPLEX 2.90 Å 1KMC 1KMC 1KMC 1KMC 1KMC 1KMC
complex with caspase-9 2.40 Å 1NW9 1NW9 1NW9 1NW9 1NW9 1NW9 Shiozaki et al., 2003