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Literature for inhibitor I32.004: XIAP caspase inhibitor

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Pharma

(Topics flags: S Structure, I Inhibitor, K Knockout, U Therapeutic, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Sun,N., Wang,S., Liu,J., Zhang,P., Chang,Y., Li,H., Zhao,K., Liu,Y., Huang,M., Hu,Y., Lin,Z., Lu,Y., Jiang,G., Chen,W., Huang,C. and Jin,H.
    XIAP promotes metastasis of bladder cancer cells by ubiquitylating YTHDC1
    Cell Death Dis16, 205-205. PubMed  Europe PubMed DOI
    2. 2022
  2. Hanifeh,M. and Ataei,F.
    XIAP as a multifaceted molecule in Cellular Signaling
    Apoptosis27, 441-453. PubMed  Europe PubMed DOI  V
  3. Qiao,H., Tian,Y., Huo,Y. and Man,H.Y.
    Role of the DUB enzyme USP7 in dendritic arborization, neuronal migration, and autistic-like behaviors in mice
    iScience25, 104595-104595. PubMed  Europe PubMed DOI  K
  4. Saha,G., Sarkar,S., Mohanta,P.S., Kumar,K., Chakrabarti,S., Basu,M. and Ghosh,M.K.
    USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma
    Oncogene41, 5061-5075. PubMed  Europe PubMed DOI
    5. 2018
  5. Yun,S.E., Nam,M.K. and Rhim,H.
    Quantitative biochemical characterization and biotechnological production of caspase modulator, XIAP: therapeutic implications for apoptosis-associated diseases
    Biochim Biophys Acta1862, 1602-1611. PubMed  Europe PubMed DOI
    6. 2017
  6. Tamanini,E., Buck,I.M., Chessari,G., Chiarparin,E., Day,J.E.H., Frederickson,M., Griffiths-Jones,C.M., Hearn,K., Heightman,T.D., Iqbal,A., Johnson,C.N., Lewis,E.J., Martins,V., Peakman,T., Reader,M., Rich,S.J., Ward,G.A., Williams,P.A. and Wilsher,N.E.
    Discovery of a potent nonpeptidomimetic, small-molecule antagonist of cellular inhibitor of apoptosis protein 1 (cIAP1) and X-linked inhibitor of apoptosis protein (XIAP)
    J Med Chem60, 4611-4625. PubMed  Europe PubMed DOI
    7. 2015
  7. Elsawy,M.A., Tikhonova,I.G., Martin,L. and Walker,B.
    Smac-derived aza-peptide as an aminopeptidase-resistant XIAP BIR3 antagonist
    Protein Pept Lett22, 836-843. PubMed  Europe PubMed
  8. Seigal,B.A., Connors,W.H., Fraley,A., Borzilleri,R.M., Carter,P.H., Emanuel,S.L., Fargnoli,J., Kim,K., Lei,M., Naglich,J.G., Pokross,M.E., Posy,S.L., Shen,H., Surti,N., Talbott,R., Zhang,Y. and Terrett,N.K.
    The discovery of macrocyclic XIAP antagonists from a DNA-programmed chemistry library, and their optimization to give lead compounds with in vivo antitumor activity
    J Med Chem58, 2855-2861. PubMed  Europe PubMed DOI  S
  9. Wu,W., Wan,O.W. and Chung,K.K.
    S-nitrosylation of XIAP at Cys 213 of BIR2 domain impairs XIAP's anti-caspase 3 activity and anti-apoptotic function
    Apoptosis20, 491-499. PubMed  Europe PubMed DOI
    10. 2013
  10. Guicciardi,M.E. and Gores,G.J.
    Unshackling caspase-7 for cancer therapy
    J Clin Invest123, 3706-3708. PubMed  Europe PubMed DOI
  11. Lin,Y.F., Lai,T.C., Chang,C.K., Chen,C.L., Huang,M.S., Yang,C.J., Liu,H.G., Dong,J.J., Chou,Y.A., Teng,K.H., Chen,S.H., Tian,W.T., Jan,Y.H., Hsiao,M. and Liang,P.H.
    Targeting the XIAP/caspase-7 complex selectively kills caspase-3-deficient malignancies
    J Clin Invest123, 3861-3875. PubMed  Europe PubMed DOI
  12. Unsain,N., Higgins,J.M., Parker,K.N., Johnstone,A.D. and Barker,P.A.
    XIAP regulates caspase activity in degenerating axons
    Cell Rep4, 751-763. PubMed  Europe PubMed DOI
    13. 2011
  13. Hornle,M., Peters,N., Thayaparasingham,B., Vorsmann,H., Kashkar,H. and Kulms,D.
    Caspase-3 cleaves XIAP in a positive feedback loop to sensitize melanoma cells to TRAIL-induced apoptosis
    Oncogene30, 575-587. PubMed  Europe PubMed DOI
    14. 2010
  14. Abhari,B.A. and Davoodi,J.
    BIR2 domain of XIAP plays a marginal role in inhibition of executioner caspases
    Int J Biol Macromol46, 337-341. PubMed  Europe PubMed DOI
  15. Nakamura,T., Wang,L., Wong,C.C., Scott,F.L., Eckelman,B.P., Han,X., Tzitzilonis,C., Meng,F., Gu,Z., Holland,E.A., Clemente,A.T., Okamoto,S.I., Salvesen,G.S., Riek,R., Yates,J.R., III and Lipton,S.A.
    Transnitrosylation of XIAP regulates caspase-dependent neuronal cell death
    Mol Cell39, 184-195. PubMed  Europe PubMed DOI
    16. 2009
  16. Cossu,F., Milani,M., Mastrangelo,E., Vachette,P., Servida,F., Lecis,D., Canevari,G., Delia,D., Drago,C., Rizzo,V., Manzoni,L., Seneci,P., Scolastico,C. and Bolognesi,M.
    Structural basis for bivalent Smac-mimetics recognition in the IAP protein family
    J Mol Biol392, 630-644. PubMed  Europe PubMed DOI  S
  17. Cossu,F., Mastrangelo,E., Milani,M., Sorrentino,G., Lecis,D., Delia,D., Manzoni,L., Seneci,P., Scolastico,C. and Bolognesi,M.
    Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2
    Biochem Biophys Res Commun378, 162-167. PubMed  Europe PubMed DOI  S
    18. 2008
  18. Abhari,B.A. and Davoodi,J.
    A mechanistic insight into SMAC peptide interference with XIAP-Bir2 inhibition of executioner caspases
    J Mol Biol381, 645-654. PubMed  Europe PubMed DOI
  19. Cillessen,S.A., Reed,J.C., Welsh,K., Pinilla,C., Houghten,R., Hooijberg,E., Deurhof,J., Castricum,K.C., Kortman,P., Hess,C.J., Ossenkoppele,G.J., Meijer,C.J. and Oudejans,J.J.
    Small-molecule XIAP antagonist restores caspase-9 mediated apoptosis in XIAP-positive diffuse large B-cell lymphoma cells
    Blood111, 369-375. PubMed  Europe PubMed DOI
  20. Mastrangelo,E., Cossu,F., Milani,M., Sorrentino,G., Lecis,D., Delia,D., Manzoni,L., Drago,C., Seneci,P., Scolastico,C., Rizzo,V. and Bolognesi,M.
    Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo[5.3.0]alkane smac mimetics. Structure, activity, and recognition principles
    J Mol Biol384, 673-689. PubMed  Europe PubMed DOI  S
  21. Nikolovska-Coleska,Z., Meagher,J.L., Jiang,S., Yang,C.Y., Qiu,S., Roller,P.P., Stuckey,J.A. and Wang,S.
    Interaction of a cyclic, bivalent smac mimetic with the X-linked inhibitor of apoptosis protein
    Biochemistry47, 9811-9824. PubMed  Europe PubMed DOI
  22. Paulsen,M., Ussat,S., Jakob,M., Scherer,G., Lepenies,I., Schutze,S., Kabelitz,D. and Adam-Klages,S.
    Interaction with XIAP prevents full caspase-3/-7 activation in proliferating human T lymphocytes
    Eur J Immunol38, 1979-1987. PubMed  Europe PubMed DOI
  23. Sun,H., Stuckey,J.A., Nikolovska-Coleska,Z., Qin,D., Meagher,J.L., Qiu,S., Lu,J., Yang,C.Y., Saito,N.G. and Wang,S.
    Structure-based design, synthesis, evaluation, and crystallographic studies of conformationally constrained Smac mimetics as inhibitors of the X-linked inhibitor of apoptosis protein (XIAP)
    J Med Chem51, 7169-7180. PubMed  Europe PubMed DOI  S
    24. 2007
  24. Davoodi,J., Mohammad-Gholi,A., Es-Haghi,A. and Mackenzie,A.
    W323S variant of Xiap-Bir3 binds to SMAC but not caspase-9
    J Biochem141, 293-299. PubMed  Europe PubMed DOI
  25. Denault,J.B., Eckelman,B.P., Shin,H., Pop,C. and Salvesen,G.S.
    Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)-mediated inhibition of caspase 9
    Biochem J405, 11-19. PubMed  Europe PubMed DOI
  26. Gao,Z., Tian,Y., Wang,J., Yin,Q., Wu,H., Li,Y.M. and Jiang,X.
    A dimeric Smac/Diablo peptide directly relieves caspase-3 inhibition by XIAP. Dynamic and cooperative regulation of XIAP by Smac/Diablo
    J Biol Chem282, 30718-30727. PubMed  Europe PubMed DOI
  27. Lin,S.C., Huang,Y., Lo,Y.C., Lu,M. and Wu,H.
    Crystal structure of the BIR1 domain of XIAP in two crystal forms
    J Mol Biol372, 847-854. PubMed  Europe PubMed DOI  S
  28. Lu,M., Lin,S.C., Huang,Y., Kang,Y.J., Rich,R., Lo,Y.C., Myszka,D., Han,J. and Wu,H.
    XIAP induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1 dimerization
    Mol Cell26, 689-702. PubMed  Europe PubMed DOI
  29. Wang,X.H., Hu,J., Du,J. and Klein,J.D.
    X-Chromosome linked inhibitor of apoptosis protein inhibits muscle proteolysis in insulin-deficient mice
    Gene Ther14, 711-720. PubMed  Europe PubMed DOI  U
  30. Wist,A.D., Gu,L., Riedl,S.J., Shi,Y. and McLendon,G.L.
    Structure-activity based study of the Smac-binding pocket within the BIR3 domain of XIAP
    Bioorg Med Chem15, 2935-2943. PubMed  Europe PubMed DOI  S
    31. 2006
  31. Eckelman,B.P., Salvesen,G.S. and Scott,F.L.
    Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family
    EMBO Rep7, 988-994. PubMed  Europe PubMed DOI
    32. 2005
  32. [YEAR:1-2-2005]Carter,B.Z., Gronda,M., Wang,Z., Welsh,K., Pinilla,C., Andreeff,M., Schober,W.D., Nefzi,A., Pond,G.R., Mawji,I.A., Houghten,R.A., Ostresh,J., Brandwein,J., Minden,M.D., Schuh,A.C., Wells,R.A., Messner,H., Chun,K., Reed,J.C. and Schimmer,A.D.
    Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells
    Blood105, 4043-4050. PubMed  Europe PubMed DOI
  33. [YEAR:13-1-2005]Scott,F.L., Denault,J.B., Riedl,S.J., Shin,H., Renatus,M. and Salvesen,G.S.
    XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs
    EMBO J24, 645-655. PubMed  Europe PubMed DOI
    34. 2004
  34. [YEAR:24-6-2004]Dohi,T., Okada,K., Xia,F., Wilford,C.E., Samuel,T., Welsh,K., Marusawa,H., Zou,H., Armstrong,R., Matsuzawa,S., Salvesen,G.S., Reed,J.C. and Altieri,D.C.
    An IAP-IAP complex inhibits apoptosis
    J Biol Chem279, 34087-34090. PubMed  Europe PubMed DOI
  35. [YEAR:29-12-2004]Lewis,J., Burstein,E., Reffey,S.B., Bratton,S.B., Roberts,A.B. and Duckett,C.S.
    Uncoupling of the signaling and caspase-inhibitory properties of X-linked inhibitor of apoptosis
    J Biol Chem279, 9023-9029. PubMed  Europe PubMed DOI
  36. Schimmer,A.D., Welsh,K., Pinilla,C., Wang,Z., Krajewska,M., Bonneau,M.J., Pedersen,I.M., Kitada,S., Scott,F.L., Bailly-Maitre,B., Glinsky,G., Scudiero,D., Sausville,E., Salvesen,G., Nefzi,A., Ostresh,J.M., Houghten,R.A. and Reed,J.C.
    Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity
    Cancer Cell5, 25-35. PubMed  Europe PubMed DOI
  37. [YEAR:12-8-2004]Sun,H., Nikolovska-Coleska,Z., Yang,C.Y., Xu,L., Tomita,Y., Krajewski,K., Roller,P.P. and Wang,S.
    Structure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondria-derived activator of caspase that target the X-linked inhibitor of apoptosis protein/caspase-9 interaction site
    J Med Chem47, 4147-4150. PubMed  Europe PubMed DOI
  38. [YEAR:27-8-2004]Wang,Z., Cuddy,M., Samuel,T., Welsh,K., Schimmer,A., Hanaii,F., Houghten,R., Pinilla,C. and Reed,J.C.
    Cellular, biochemical, and genetic analysis of mechanism of small molecule IAP inhibitors
    J Biol Chem279, 48168-48176. PubMed  Europe PubMed DOI
    39. 2003
  39. Hell,K., Saleh,M., Crescenzo,G.D., O'Connor-McCourt,M.D. and Nicholson,D.W.
    Substrate cleavage by caspases generates protein fragments with Smac/Diablo-like activities
    Cell Death Differ10, 1234-1239. PubMed  Europe PubMed DOI
  40. [YEAR:21-7-2003]Kashkar,H., Haefs,C., Shin,H., Hamilton-Dutoit,S.J., Salvesen,G.S., Kronke,M. and Jurgensmeier,J.M.
    XIAP-mediated caspase inhibition in Hodgkin's lymphoma-derived B cells
    J Exp Med198, 341-347. PubMed  Europe PubMed DOI
  41. [YEAR:24-11-2003]Potts,P.R., Singh,S., Knezek,M., Thompson,C.B. and Deshmukh,M.
    Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis
    J Cell Biol163, 789-799. PubMed  Europe PubMed DOI
  42. [YEAR:1-8-2003]Shin,H., Okada,K., Wilkinson,J.C., Solomon,K.M., Duckett,C.S., Reed,J.C. and Salvesen,G.S.
    Identification of ubiquitination sites on the X-linked inhibitor of apoptosis protein
    Biochem J373, 965-971. PubMed  Europe PubMed DOI
  43. Shiozaki,E.N., Chai,J., Rigotti,D.J., Riedl,S.J., Li,P., Srinivasula,S.M., Alnemri,E.S., Fairman,R. and Shi,Y.
    Mechanism of XIAP-mediated inhibition of caspase-9
    Mol Cell11, 519-527. PubMed  Europe PubMed DOI  S
  44. [YEAR:22-8-2003]Srinivasula,S.M., Gupta,S., Datta,P., Zhang,Z., Hegde,R., Cheong,N., Fernandes-Alnemri,T. and Alnemri,E.S.
    Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2
    J Biol Chem278, 31469-31472. PubMed  Europe PubMed DOI
  45. [YEAR:18-4-2003]Tamm,I., Trepel,M., Cardo-Vila,M., Sun,Y., Welsh,K., Cabezas,E., Swatterthwait,A., Arap,W., Reed,J.C. and Pasqualini,R.
    Peptides targeting caspase inhibitors
    J Biol Chem278, 14401-14405. PubMed  Europe PubMed DOI
  46. [YEAR:9-5-2003]Vaux,D.L. and Silke,J.
    Mammalian mitochondrial IAP binding proteins
    Biochem Biophys Res Commun304, 499-504. PubMed  Europe PubMed DOI
    47. 2002
  47. [YEAR:4-1-2002]Hegde,R., Srinivasula,S.M., Zhang,Z., Wassell,R., Mukattash,R., Cilenti,L., Dubois,G., Lazebnik,Y., Zervos,A.S., Fernandes-Alnemri,T. and Alnemri,E.S.
    Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction
    J Biol Chem277, 432-438. PubMed  Europe PubMed DOI
  48. Hofmann,H.S., Simm,A., Hammer,A., Silber,R.E. and Bartling,B.
    Expression of inhibitors of apoptosis (IAP) proteins in non-small cell human lung cancer
    J Cancer Res Clin Oncol128, 554-560. PubMed  Europe PubMed DOI
  49. [YEAR:4-1-2002]Martins,L.M., Iaccarino,I., Tenev,T., Gschmeissner,S., Totty,N.F., Lemoine,N.R., Savopoulos,J., Gray,C.W., Creasy,C.L., Dingwall,C. and Downward,J.
    The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif
    J Biol Chem277, 439-444. PubMed  Europe PubMed DOI
  50. [YEAR:20-3-2002]Sauerwald,T.M., Betenbaugh,M.J. and Oyler,G.A.
    Inhibiting apoptosis in mammalian cell culture using the caspase inhibitor XIAP and deletion mutants
    Biotechnol Bioeng77, 704-716. PubMed  Europe PubMed DOI
  51. [YEAR:1-4-2002]Silke,J., Hawkins,C.J., Ekert,P.G., Chew,J., Day,C.L., Pakusch,M., Verhagen,A.M. and Vaux,D.L.
    The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites
    J Cell Biol157, 115-124. PubMed  Europe PubMed DOI
  52. Stennicke,H.R., Ryan,C.A. and Salvesen,G.S.
    Reprieval from execution: the molecular basis of caspase inhibition
    Trends Biochem Sci27, 94-101. PubMed  Europe PubMed DOI
  53. Van Loo,G., van Gurp,M., Depuydt,B., Srinivasula,S.M., Rodriguez,I., Alnemri,E.S., Gevaert,K., Vandekerckhove,J., Declercq,W. and Vandenabeele,P.
    The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity
    Cell Death Differ9, 20-26. PubMed  Europe PubMed DOI
  54. [YEAR:4-1-2002]Verhagen,A.M., Silke,J., Ekert,P.G., Pakusch,M., Kaufmann,H., Connolly,L.M., Day,C.L., Tikoo,A., Burke,R., Wrobel,C., Moritz,R.L., Simpson,R.J. and Vaux,D.L.
    HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins
    J Biol Chem277, 445-454. PubMed  Europe PubMed DOI
  55. [YEAR:5-4-2002]Vucic,D., Deshayes,K., Ackerly,H., Pisabarro,M.T., Kadkhodayan,S., Fairbrother,W.J. and Dixit,V.M.
    SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP)
    J Biol Chem277, 12275-12279. PubMed  Europe PubMed DOI
    56. 2001
  56. [YEAR:1-3-2001]Bratton,S.B., Walker,G., Srinivasula,S.M., Sun,X.M., Butterworth,M., Alnemri,E.S. and Cohen,G.M.
    Recruitment, activation and retention of caspases-9 and-3 by Apaf-1 apoptosome and associated XIAP complexes
    EMBO J20, 998-1009. PubMed  Europe PubMed DOI
  57. [YEAR:9-3-2001]Chai,J.J., Shiozaki,E., Srinivasula,S.M., Wu,Q., Dataa,P., Alnemri,E.S. and Shi,Y.G.
    Structural basis of caspase-7 inhibition by XIAP
    Cell104, 769-780. PubMed  Europe PubMed  S  I
  58. [YEAR:9-3-2001]Huang,Y.H., Park,Y.C., Rich,R.L., Segal,D., Myszka,D.G. and Wu,H.
    Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain
    Cell104, 781-790. PubMed  Europe PubMed  S
  59. [YEAR:9-3-2001]Riedl,S.J., Renatus,M., Schwarzenbacher,R., Zhou,Q., Sun,C., Fesik,S.W., Liddington,R.C. and Salvesen,G.S.
    Structural basis for the inhibition of caspase-3 by XIAP
    Cell104, 791-800. PubMed  Europe PubMed  S
  60. [YEAR:1-3-2001]Srinivasula,S.M., Hegde,R., Saleh,A., Datta,P., Shiozaki,E., Chai,J., Lee,R.A., Robbins,P.D., Fernandes-Alnemri,T., Shi,Y. and Alnemri,E.S.
    A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
    Nature410, 112-116. PubMed  Europe PubMed DOI
  61. [YEAR:20-7-2001]Suzuki,Y., Nakabayashi,Y., Nakata,K., Reed,J.C. and Takahashi,R.
    X-linked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and-7 in distinct modes
    J Biol Chem276, 27058-27063. PubMed  Europe PubMed DOI
    62. 2000
  62. [YEAR:13-10-2000]Datta,R., Oki,E., Endo,K., Biedermann,V., Ren,J. and Kufe,D.
    XIAP regulates DNA damage-induced apoptosis downstream of caspase-9 cleavage
    J Biol Chem275, 31733-31738. PubMed  Europe PubMed DOI
  63. Deveraux,Q.L., Welsh,K. and Reed,J.C.
    Purification and use of recombinant inhibitor of apoptosis proteins as caspase inhibitors
    Methods Enzymol322, 154-161. PubMed  Europe PubMed  V
  64. [YEAR:27-10-2000]Sun,C., Cai,M., Meadows,R.P., Xu,N., Gunasekera,A.H., Herrmann,J., Wu,J.C. and Fesik,S.W.
    NMR structure and mutagenesis of the third Bir domain of the inhibitor of apoptosis protein XIAP
    J Biol Chem275, 33777-33781. PubMed  Europe PubMed DOI  S
    65. 1999
  65. [YEAR:1-10-1999]Deveraux,Q.L., Leo,E., Stennicke,H.R., Welsh,K., Salvesen,G.S. and Reed,J.C.
    Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases
    EMBO J18, 5242-5251. PubMed  Europe PubMed DOI
  66. Sun,C., Cai,M., Gunasekera,A.H., Meadows,R.P., Wang,H., Chen,J., Zhang,H., Wu,W., Xu,N., Ng,S.C. and Fesik,S.W.
    NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP
    Nature401, 818-822. PubMed  Europe PubMed DOI
    67. 1998
  67. [YEAR:15-4-1998]Deveraux,Q.L., Roy,N., Stennicke,H.R., Van Arsdale,T., Zhou,Q., Srinivasula,S.M., Alnemri,E.S., Salvesen,G.S. and Reed,J.C.
    IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
    EMBO J17, 2215-2223. PubMed  Europe PubMed DOI
    68. 1997
  68. [YEAR:17-7-1997]Deveraux,Q.L., Takahashi,R., Salvesen,G.S. and Reed,J.C.
    X-linked IAP is a direct inhibitor of cell-death proteases
    Nature388, 300-304. PubMed  Europe PubMed DOI
  69. [YEAR:15-6-1997]Farahani,R., Fong,W.G., Korneluk,R.G. and MacKenzie,A.E.
    Genomic organization and primary characterization of mIAP-3: the murine homologue of human X-linked IAP
    Genomics42, 514-518. PubMed  Europe PubMed DOI
    70. 1996
  70. [YEAR:1-11-1996]Rajcan-Separovic,E., Liston,P., Lefebvre,C. and Korneluk,R.G.
    Assignment of human inhibitor of apoptosis protein (IAP) genes xiap, hiap-1, and hiap-2 to chromosomes Xq25 and 11q22-q23 by fluorescence in situ hybridization
    Genomics37, 404-406. PubMed  Europe PubMed DOI
  71. Uren,A.G., Pakusch,M., Hawkins,C.J., Puls,K.L. and Vaux,D.L.
    Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors
    Proc Natl Acad Sci U S A93, 4974-4978. PubMed  Europe PubMed

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