Structure for inhibitor I04.002: alpha-1-antichymotrypsin

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature

TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
Homo sapiens
Ala249Arg mutant; cleaved form	2.10 Å	1AS4	1AS4	1AS4	1AS4	1AS4	1AS4	Lukacs et al., 1998
alpha1-antichymotrypsin serpin in the delta conformation (partial loop insertion)	2.27 Å	1QMN	1QMN	1QMN	1QMN	1QMN	1QMN	Gooptu et al., 2000
Cleaved form	2.70 Å	2ACH	2ACH	2ACH	2ACH	2ACH	2ACH	Baumann et al., 1991
Ala347Arg mutant; cleaved form	2.40 Å	3CAA	3CAA	3CAA	3CAA	3CAA	3CAA	Lukacs et al., 1996
mature inhibitor	2.70 Å	3DLW	3DLW	3DLW	3DLW	3DLW	3DLW
Thr345Arg mutant; cleaved form	2.90 Å	4CAA	4CAA	4CAA	4CAA	4CAA	4CAA	Lukacs et al., 1996
crystal structure of alpha1-antichymotrypsin variant dbs-i1: a drug- binding serpin for doxycycline	1.47 Å	5OM2	5OM2	5OM2	5OM2	5OM2	5OM2
crystal structure of alpha1-antichymotrypsin variant dbs-i5: a mmp14- cleavable drug-binding serpin for doxycycline	2.00 Å	5OM3	5OM3	5OM3	5OM3	5OM3	5OM3
crystal structure of alpha1-antichymotrypsin variant dbs-i-allo1: an allosterically triggered drug-binding serpin for doxycycline	1.60 Å	5OM5	5OM5	5OM5	5OM5	5OM5	5OM5
crystal structure of alpha1-antichymotrypsin variant dbs-i-allo2: a mmp9-cleavable drug-binding serpin for doxycycline	1.85 Å	5OM6	5OM6	5OM6	5OM6	5OM6	5OM6
crystal structure of alpha1-antichymotrypsin variant dbs-ii: a drug- binding serpin for doxorubicin	1.73 Å	5OM7	5OM7	5OM7	5OM7	5OM7	5OM7
crystal form 2 of alpha1-antichymotrypsin variant dbs-ii-allo: an allosterically modulated drug-binding serpin for doxorubicin	2.20 Å	5OM8	5OM8	5OM8	5OM8	5OM8	5OM8
crystal form 1 of alpha1-antichymotrypsin variant dbs-ii-allo: an allosterically modulated drug-binding serpin for doxorubicin	1.80 Å	6FTP	6FTP	6FTP	6FTP	6FTP	6FTP
crystal structure of alpha1-antichymotrypsin variant newbg-0: a new binding globulin variant that is devoid of any cortisol-binding capabilities	1.90 Å	6HGD	6HGD	6HGD	6HGD	6HGD	6HGD
crystal structure of alpha1-antichymotrypsin variant newbg-i in the uncleaved s-conformation	2.80 Å	6HGE	6HGE	6HGE	6HGE	6HGE	6HGE
variant newbg-II; complex with cortisol	1.65 Å	6HGF	6HGF	6HGF	6HGF	6HGF	6HGF
variant newbg-III; complex with cortisol	1.79 Å	6HGG	6HGG	6HGG	6HGG	6HGG	6HGG
crystal structure of alpha1-antichymotrypsin variant newbg-iii: a new binding globulin without any bound ligand	1.90 Å	6HGH	6HGH	6HGH	6HGH	6HGH	6HGH
variant newbg-III; complex with corticosterone	1.52 Å	6HGI	6HGI	6HGI	6HGI	6HGI	6HGI
variant newbg-III; complex with aldosterone	1.83 Å	6HGJ	6HGJ	6HGJ	6HGJ	6HGJ	6HGJ
variant newbg-III; complex with progesterone	1.86 Å	6HGK	6HGK	6HGK	6HGK	6HGK	6HGK
variant newbg-III; complex with testosterone	1.92 Å	6HGL	6HGL	6HGL	6HGL	6HGL	6HGL
crystal structure of alpha1-antichymotrypsin variant newbg-iii-allo: an allosterically controlled new binding globulin with an unprecedentedly high ligand release efficacy	1.37 Å	6HGM	6HGM	6HGM	6HGM	6HGM	6HGM
crystal structure of alpha1-antichymotrypsin variant dbs-ii-allo-l55v:an allosterically controlled doxorubicin-binding serpin with an unprecedentedly high ligand release efficacy	1.48 Å	6HGN	6HGN	6HGN	6HGN	6HGN	6HGN