Literature for BMS-299897 (A22.001 inhibitor)

(Topics flags: I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

2008
1. Burton,C.R., Meredith,J.E., Barten,D.M., Goldstein,M.E., Krause,C.M., Kieras,C.J., Sisk,L., Iben,L.G., Polson,C., Thompson,M.W., Lin,X.A., Corsa,J., Fiedler,T., Pierdomenico,M., Cao,Y., Roach,A.H., Cantone,J.L., Ford,M.J., Drexler,D.M., Olson,R.E., Yang,M.G., Bergstrom,C.P., McElhone,K.E., Bronson,J.J., Macor,J.E., Blat,Y., Grafstrom,R.H., Stern,A.M., Seiffert,D.A., Zaczek,R., Albright,C.F. and Toyn,J.H.
   The amyloid-beta rise and gamma-secretase inhibitor potency depend on the level of substrate expression
   J Biol Chem283, 22992-23003. PubMed  Europe PubMed DOI  I
2. Zhao,B., Yu,M., Neitzel,M., Marugg,J., Jagodzinski,J., Lee,M., Hu,K., Schenk,D., Yednock,T. and Basi,G.
   Identification of gamma-secretase inhibitor potency determinants on presenilin
   J Biol Chem283, 2927-2938. PubMed  Europe PubMed DOI  I
2006
3. [YEAR:11-8-2006]Clarke,E.E., Churcher,I., Ellis,S., Wrigley,J.D., Lewis,H.D., Harrison,T., Shearman,M.S. and Beher,D.
   Intra- or intercomplex binding to the gamma-secretase enzyme. A model to differentiate inhibitor classes
   J Biol Chem281, 31279-31289. PubMed  Europe PubMed DOI  I
2005
4. [YEAR:15-2-2005]Anderson,J.J., Holtz,G., Baskin,P.P., Turner,M., Rowe,B., Wang,B., Kounnas,M.Z., Lamb,B.T., Barten,D., Felsenstein,K., McDonald,I., Srinivasan,K., Munoz,B. and Wagner,S.L.
   Reductions in beta-amyloid concentrations in vivo by the gamma-secretase inhibitors BMS-289948 and BMS-299897
   Biochem Pharmacol69, 689-698. PubMed  Europe PubMed DOI  I
5. [YEAR:27-9-2005]Barten,D.M., Guss,V.L., Corsa,J.A., Loo,A., Hansel,S.B., Zheng,M., Munoz,B., Srinivasan,K., Wang,B., Robertson,B.J., Polson,C.T., Wang,J., Roberts,S.B., Hendrick,J.P., Anderson,J.J., Loy,J.K., Denton,R., Verdoorn,T.A., Smith,D.W. and Felsenstein,K.M.
   Dynamics of {beta}-amyloid reductions in brain, cerebrospinal fluid, and plasma of {beta}-amyloid precursor protein transgenic mice treated with a {gamma}-secretase inhibitor
   J Pharmacol Exp Ther312, 635-643. PubMed  Europe PubMed DOI  I