Literature for inhibitor I39.950: complement component C3

(Topics flags: S Structure, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Cao,Q., Li,J. and Zhang,K.
   The Role of Complement Component 3 (C3) in Psoriasis
   Curr Mol Pharmacol (2025) PubMed  Europe PubMed DOI  V
2. Gadeberg,T.A.F., Jorgensen,M.H., Olesen,H.G., Lorentzen,J., Harwood,S.L., Almeida,A.V., Fruergaard,M.U., Jensen,R.K., Kanis,P., Pedersen,H., Tranchant,E., Petersen,S.V., Thogersen,I.B., Kragelund,B.B., Lyons,J.A., Enghild,J.J. and Andersen,G.R.
   Cryo-EM analysis of complement C3 reveals a reversible major opening of the macroglobulin ring
   Nat Struct Mol Biol (2025) PubMed  Europe PubMed DOI
3. Han,Q., Zhang,Q., Wu,D., Yang,Z., Huang,J., Wang,Z., Zou,H., Peng,Q., Meng,Y., Jiang,Y., Xiao,J. and Hu,R.
   LPS-Induced Intracellular Complement 3 Activation Regulated ATP Production in Yak Rumen Epithelial Cells
   Vet Sci (2025) 12 PubMed  Europe PubMed DOI  PMC  EPMC
4. West,E.E. and Kemper,C.
   A cut above: atypical proteolysis endows complement C3 with non-canonical immune activities
   EMBO J (2025) PubMed  Europe PubMed DOI
2024
5. Dai,X., Yang,J., Lv,L., Wang,C. and Bian,L.
   Molecular recognition and binding between human plasminogen Kringle 5 and alpha-chain of human complement component C3b by frontal chromatography and dynamics simulation
   J Chromatogr A (2024) 1718, 464673-464673. PubMed  Europe PubMed DOI
6. Sahu,S.K., Maurya,R.K. and Kulkarni,H.S.
   The Role of Complement Component C3 in Protection Against Pseudomonas Pneumonia-Induced Lung Injury
   DNA Cell Biol (2024) 43, 153-157. PubMed  Europe PubMed DOI  PMC  EPMC  V
2022
7. Geisbrecht,B.V., Lambris,J.D. and Gros,P.
   Complement component C3: A structural perspective and potential therapeutic implications
   Semin Immunol (2022) , 101627-101627. PubMed  Europe PubMed DOI  V
2021
8. Lu,S.Y., Fu,C.L., Liang,L., Yang,B., Shen,W., Wang,Q.W., Chen,Y., Chen,Y.F., Liu,Y.N., Zhu,L., Zhao,J., Shi,W., Mi,S. and Yao,J.
   miR-218-2 regulates cognitive functions in the hippocampus through complement component 3-dependent modulation of synaptic vesicle release
   Proc Natl Acad Sci U S A (2021) 118 PubMed  Europe PubMed DOI  PMC  EPMC
2020
9. Harwood,S.L., Nielsen,N.S., Pedersen,H., Kjoge,K., Nielsen,P.K., Andersen,G.R. and Enghild,J.J.
   Substituting the Thiol Ester of Human A2M or C3 with a Disulfide Produces Native Proteins with Altered Proteolysis-Induced Conformational Changes
   Biochemistry (2020) PubMed  Europe PubMed DOI
10. Schafer,N., Wolf,H.N., Enzbrenner,A., Schikora,J., Reichenthaler,M., Enzmann,V. and Pauly,D.
    Properdin Modulates Complement Component Production in Stressed Human Primary Retinal Pigment Epithelium Cells
    Antioxidants (Basel) (2020) 9 PubMed  Europe PubMed DOI
11. Zheng,Q.Y., Liang,S.J., Xu,F., Yang,Y., Feng,J.L., Shen,F., Zhong,Y., Wu,S., Shu,Y., Sun,D.D. and Xu,G.L.
    Complement component 3 prevents imiquimod-induced psoriatic skin inflammation by inhibiting apoptosis in mice
    Int Immunopharmacol (2020) 85, 106692-106692. PubMed  Europe PubMed DOI
2012
12. Holm,L., Ackland,G.L., Edwards,M.R., Breckenridge,R.A., Sim,R.B. and Offer,J.
    Chemical labelling of active serum thioester proteins for quantification
    Immunobiology (2012) 217, 256-264. PubMed  Europe PubMed DOI
2006
13. Abdul Ajees,A., Gunasekaran,K., Volanakis,J.E., Narayana,S.V., Kotwal,G.J. and Murthy,H.M.
    The structure of complement C3b provides insights into complement activation and regulation
    Nature (2006) 444, 221-225. PubMed  Europe PubMed DOI  S
14. Janssen,B.J., Christodoulidou,A., McCarthy,A., Lambris,J.D. and Gros,P.
    Structure of C3b reveals conformational changes that underlie complement activity
    Nature (2006) 444, 213-216. PubMed  Europe PubMed DOI  S
2005
15. [YEAR:22-9-2005]Janssen,B.J., Huizinga,E.G., Raaijmakers,H.C., Roos,A., Daha,M.R., Nilsson-Ekdahl,K., Nilsson,B. and Gros,P.
    Structures of complement component C3 provide insights into the function and evolution of immunity
    Nature (22-9-2005) 437, 505-511. PubMed  Europe PubMed DOI  S
1998
16. Armstrong,P.B., Melchior,R., Swarnakar,S. and Quigley,J.P.
    alpha2-Macroglobulin does not function as a C3 homologue in the plasma hemolytic system of the American horseshoe crab, Limulus
    Mol Immunol (1998) 35, 47-53. PubMed  Europe PubMed DOI
17. [YEAR:15-7-1998]Gadjeva,M., Dodds,A.W., Taniguchi-Sidle,A., Willis,A.C., Isenman,D.E. and Law,S.K.
    The covalent binding reaction of complement component C3
    J Immunol (15-7-1998) 161, 985-990. PubMed  Europe PubMed