Literature for inhibitor I32.007: BIRC-7 protein

(Topics flags: S Structure, T Target, R Splicing, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2020
1. Jin,Q., Lin,C., Zhu,X., Cao,Y., Guo,C. and Wang,L.
   (125)I seeds irradiation inhibits tumor growth and induces apoptosis by Ki-67, P21, survivin, livin and caspase-9 expression in lung carcinoma xenografts
   Radiat Oncol15, 238-238. PubMed  Europe PubMed DOI
2019
2. Ge,Y., Liu,B.L., Cui,J.P. and Li,S.Q.
   Livin regulates H2A.X(Y142) phosphorylation and promotes autophagy in colon cancer cells via a novel kinase activity
   Front Oncol9, 1233-1233. PubMed  Europe PubMed DOI
3. Ge,Y., Liu,B.L., Cui,J.P. and Li,S.Q.
   Livin promotes colon cancer progression by regulation of H2A.X(Y39ph) via JMJD6
   Life Sci234, 116788-116788. PubMed  Europe PubMed DOI
2018
4. Johnson,C.N., Ahn,J.S., Buck,I.M., Chiarparin,E., Day,J.E.H., Hopkins,A., Howard,S., Lewis,E.J., Martins,V., Millemaggi,A., Munck,J.M., Page,L.W., Peakman,T., Reader,M., Rich,S.J., Saxty,G., Smyth,T., Thompson,N.T., Ward,G.A., Williams,P.A., Wilsher,N.E. and Chessari,G.
   A fragment-derived clinical candidate for antagonism of X-linked and cellular inhibitor of apoptosis proteins: 1-(6-[(4-fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-1 H,2 H,3 H-pyrrolo[3,2- b]pyridin-1-yl)-2-[(2 R,5 R)-5-methyl-2-([(3R)-3-methylmorpholin-4-yl]methyl)piperazin-1-yl]ethan-1-one (ASTX660)
   J Med Chem61, 7314-7329. PubMed  Europe PubMed DOI
2017
5. Tamanini,E., Buck,I.M., Chessari,G., Chiarparin,E., Day,J.E.H., Frederickson,M., Griffiths-Jones,C.M., Hearn,K., Heightman,T.D., Iqbal,A., Johnson,C.N., Lewis,E.J., Martins,V., Peakman,T., Reader,M., Rich,S.J., Ward,G.A., Williams,P.A. and Wilsher,N.E.
   Discovery of a potent nonpeptidomimetic, small-molecule antagonist of cellular inhibitor of apoptosis protein 1 (cIAP1) and X-linked inhibitor of apoptosis protein (XIAP)
   J Med Chem60, 4611-4625. PubMed  Europe PubMed DOI
2015
6. Lin,X., Li,H.R., Lin,X.F., Yu,M.E., Tu,X.W., Hua,Z.D., Lin,M., Xu,N.L., Han,L.L. and Chen,Y.S.
   Silencing of livin inhibits tumorigenesis and metastasis via VEGF and MMPs pathway in lung cancer
   Int J Oncol47, 657-667. PubMed  Europe PubMed DOI
2013
7. Abd-Elrahman,I., Deutsch,V., Pick,M., Kay,S., Neuman,T., Perlman,R. and Ben-Yehuda,D.
   Differential regulation of the apoptotic machinery during megakaryocyte differentiation and platelet production by inhibitor of apoptosis protein Livin
   Cell Death Dis4, e937-e937. PubMed  Europe PubMed DOI
8. Liu,G.H., Wang,C. and Ding,Z.Y.
   Overexpression of the truncated form of livin reveals a complex interaction with caspase-3
   Int J Oncol42, 2037-2045. PubMed  Europe PubMed DOI
2011
9. Oh,B.Y., Lee,R.A. and Kim,K.H.
   siRNA targeting Livin decreases tumor in a xenograft model for colon cancer
   World J Gastroenterol17, 2563-2571. PubMed  Europe PubMed DOI  K
10. Yan,B.
    Research progress on livin protein: an inhibitor of apoptosis
    Mol Cell Biochem357, 39-45. PubMed  Europe PubMed DOI  V
2010
11. Crnkovic-Mertens,I., Bulkescher,J., Mensger,C., Hoppe-Seyler,F. and Hoppe-Seyler,K.
    Isolation of peptides blocking the function of anti-apoptotic livin protein
    Cell Mol Life Sci67, 1895-1905. PubMed  Europe PubMed DOI
12. Dasgupta,A., Alvarado,C.S., Xu,Z. and Findley,H.W.
    Expression and functional role of inhibitor-of-apoptosis protein livin (BIRC7) in neuroblastoma
    Biochem Biophys Res Commun400, 53-59. PubMed  Europe PubMed DOI
13. Lazar,I., Yaacov,B., Shiloach,T., Eliahoo,E., Kadouri,L., Lotem,M., Perlman,R., Zakay-Rones,Z., Panet,A. and Ben-Yehuda,D.
    The oncolytic activity of Newcastle disease virus NDV-HUJ on chemoresistant primary melanoma cells is dependent on the proapoptotic activity of the inhibitor of apoptosis protein Livin
    J Virol84, 639-646. PubMed  Europe PubMed DOI
14. Wang,X., Xu,J., Ju,S., Ni,H., Zhu,J. and Wang,H.
    Livin gene plays a role in drug resistance of colon cancer cells
    Clin Biochem43, 655-660. PubMed  Europe PubMed DOI  K
15. Yang,D., Song,X., Zhang,J., Ye,L., Wang,S., Che,X., Wang,J., Zhang,Z. and Wang,L.
    Suppression of livin gene expression by siRNA leads to growth inhibition and apoptosis induction in human bladder cancer T24 cells
    Biosci Biotechnol Biochem74, 1039-1044. PubMed  Europe PubMed DOI  K
16. Yu,X.P., Zhang,Y. and Zhu,C.M.
    Effects of siRNA livin gene on growth and function of gastric cancer cell line BGC823
    Chin J Cancer Prev Treat17, 1722-1726.  K
2009
17. Abd-Elrahman,I., Hershko,K., Neuman,T., Nachmias,B., Perlman,R. and Ben-Yehuda,D.
    The inhibitor of apoptosis protein livin (ML-IAP) plays a dual role in tumorigenicity
    Cancer Res69, 5475-5480. PubMed  Europe PubMed DOI
2008
18. Wang,R., Lin,F., Wang,X., Gao,P., Dong,K., Zou,A.M., Cheng,S.Y., Wei,S.H. and Zhang,H.Z.
    Silencing Livin gene expression to inhibit proliferation and enhance chemosensitivity in tumor cells
    Cancer Gene Ther15, 402-412. PubMed  Europe PubMed DOI  K
2007
19. Chang,H. and Schimmer,A.D.
    Livin/melanoma inhibitor of apoptosis protein as a potential therapeutic target for the treatment of malignancy
    Mol Cancer Ther6, 24-30. PubMed  Europe PubMed DOI  T
20. Choi,J., Hwang,Y.K., Sung,K.W., Lee,S.H., Yoo,K.H., Jung,H.L., Koo,H.H., Kim,H.J., Kang,H.J., Shin,H.Y. and Ahn,H.S.
    Expression of livin, an antiapoptotic protein, is an independent favorable prognostic factor in childhood acute lymphoblastic leukemia
    Blood109, 471-477. PubMed  Europe PubMed DOI
21. Crnkovic-Mertens,I., Wagener,N., Semzow,J., Grone,E.F., Haferkamp,A., Hohenfellner,M., Butz,K. and Hoppe-Seyler,F.
    Targeted inhibition of Livin resensitizes renal cancer cells towards apoptosis
    Cell Mol Life Sci64, 1137-1144. PubMed  Europe PubMed DOI
22. Liu,B., Han,M., Wen,J.K. and Wang,L.
    Livin/ML-IAP as a new target for cancer treatment
    Cancer Lett250, 168-176. PubMed  Europe PubMed DOI
23. Nachmias,B., Mizrahi,S., Elmalech,M., Lazar,I., Ashhab,Y., Gazit,R., Markel,G., Ben-Yehuda,D. and Mandelboim,O.
    Manipulation of NK cytotoxicity by the IAP family member Livin
    Eur J Immunol37, 3467-3476. PubMed  Europe PubMed DOI
24. Wang,H., Tan,S.S., Wang,X.Y., Liu,D.H., Yu,C.S., Bai,Z.L., He,D.L. and Zhao,J.
    Silencing livin gene by siRNA leads to apoptosis induction, cell cycle arrest, and proliferation inhibition in malignant melanoma LiBr cells
    Acta Pharmacol Sin28, 1968-1974. PubMed  Europe PubMed DOI  K
2006
25. [YEAR:9-9-2006]Crnkovic-Mertens,I., Muley,T., Meister,M., Hartenstein,B., Semzow,J., Butz,K. and Hoppe-Seyler,F.
    The anti-apoptotic livin gene is an important determinant for the apoptotic resistance of non-small cell lung cancer cells
    Lung Cancer54, 135-142. PubMed  Europe PubMed DOI
26. [YEAR:23-6-2006]Yan,H., Brouha,B., Liu,T., Raj,D., Biddle,D., Lee,R. and Grossman,D.
    Proteolytic cleavage of livin (ML-IAP) in apoptotic melanoma cells potentially mediated by a non-canonical caspase
    J Dermatol Sci43, 189-200. PubMed  Europe PubMed DOI
27. Zobel,K., Wang,L., Varfolomeev,E., Franklin,M.C., Elliott,L.O., Wallweber,H.J., Okawa,D.C., Flygare,J.A., Vucic,D., Fairbrother,W.J. and Deshayes,K.
    Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs
    ACS Chem Biol1, 525-533. PubMed  Europe PubMed DOI  S
2005
28. [YEAR:1-2-2005]Hariu,H., Hirohashi,Y., Torigoe,T., Asanuma,H., Hariu,M., Tamura,Y., Aketa,K., Nabeta,C., Nakanishi,K., Kamiguchi,K., Mano,Y., Kitamura,H., Kobayashi,J., Tsukahara,T., Shijubo,N. and Sato,N.
    Aberrant expression and potency as a cancer immunotherapy target of inhibitor of apoptosis protein family, Livin/ML-IAP in lung cancer
    Clin Cancer Res11, 1000-1009. PubMed  Europe PubMed
29. [YEAR:15-10-2005]Vucic,D., Franklin,M.C., Wallweber,H.J., Das,K., Eckelman,B.P., Shin,H., Elliott,L.O., Kadkhodayan,S., Deshayes,K., Salvesen,G.S. and Fairbrother,W.J.
    Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP
    Biochem J385, 11-20. PubMed  Europe PubMed DOI
2003
30. [YEAR:13-11-2003]Crnkovic-Mertens,I., Hoppe-Seyler,F. and Butz,K.
    Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene
    Oncogene22, 8330-8336. PubMed  Europe PubMed DOI
31. Franklin,M.C., Kadkhodayan,S., Ackerly,H., Alexandru,D., Distefano,M.D., Elliott,L.O., Flygare,J.A., Mausisa,G., Okawa,D.C., Ong,D., Vucic,D., Deshayes,K. and Fairbrother,W.J.
    Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ML-IAP)
    Biochemistry42, 8223-8231. PubMed  Europe PubMed DOI  S
32. [YEAR:1-10-2003]Nachmias,B., Ashhab,Y., Bucholtz,V., Drize,O., Kadouri,L., Lotem,M., Peretz,T., Mandelboim,O. and Ben-Yehuda,D.
    Caspase-mediated cleavage converts Livin from an antiapoptotic to a proapoptotic factor: implications for drug-resistant melanoma
    Cancer Res63, 6340-6349. PubMed  Europe PubMed
2002
33. Sanna,M.G., da Silva Correia,J., Ducrey,O., Lee,J., Nomoto,K., Schrantz,N., Deveraux,Q.L. and Ulevitch,R.J.
    IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition
    Mol Cell Biol22, 1754-1766. PubMed  Europe PubMed DOI
34. [YEAR:5-4-2002]Vucic,D., Deshayes,K., Ackerly,H., Pisabarro,M.T., Kadkhodayan,S., Fairbrother,W.J. and Dixit,V.M.
    SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP)
    J Biol Chem277, 12275-12279. PubMed  Europe PubMed DOI
2001
35. [YEAR:20-4-2001]Ashhab,Y., Alian,A., Polliack,A., Panet,A. and Ben Yehuda,D.
    Two splicing variants of a new inhibitor of apoptosis gene with different biological properties and tissue distribution pattern
    FEBS Lett495, 56-60. PubMed  Europe PubMed DOI  R
36. [YEAR:2-2-2001]Kasof,G.M. and Gomes,B.C.
    Livin, a novel inhibitor of apoptosis protein family member
    J Biol Chem276, 3238-3246. PubMed  Europe PubMed DOI
2000
37. [YEAR:29-12-2000]Lin,J.H., Deng,G., Huang,Q. and Morser,J.
    KIAP, a novel member of the inhibitor of apoptosis protein family
    Biochem Biophys Res Commun279, 820-831. PubMed  Europe PubMed DOI
38. [YEAR:2-11-2000]Vucic,D., Stennicke,H.R., Pisabarro,M.T., Salvesen,G.S. and Dixit,V.M.
    ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas
    Curr Biol10, 1359-1366. PubMed  Europe PubMed DOI