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CHEBI:7476 - naproxen
| Formula | C14H14O3 |
| Net Charge | 0 |
| Average Mass | 230.263 |
| Monoisotopic Mass | 230.09429 |
| SMILES | COc1ccc2cc([C@H](C)C(=O)O)ccc2c1 |
| InChI | InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1 |
| InChIKey | CMWTZPSULFXXJA-VIFPVBQESA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Roles: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). |
| Biological Roles: | cyclooxygenase 2 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2. antiviral agent A substance that destroys or inhibits replication of viruses. cyclooxygenase 1 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. drug allergen Any drug which causes the onset of an allergic reaction. xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antipyretic A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever. antirheumatic drug A drug used to treat rheumatoid arthritis. anti-ulcer drug One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. drug allergen Any drug which causes the onset of an allergic reaction. gout suppressant A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout. anti-inflammatory agent Any compound that has anti-inflammatory effects. non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. vulnerary A drug used in treating and healing of wounds. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| naproxen (CHEBI:7476) has role analgesic (CHEBI:35480) |
| naproxen (CHEBI:7476) has role anti-inflammatory agent (CHEBI:67079) |
| naproxen (CHEBI:7476) has role anti-ulcer drug (CHEBI:49201) |
| naproxen (CHEBI:7476) has role antineoplastic agent (CHEBI:35610) |
| naproxen (CHEBI:7476) has role antipyretic (CHEBI:35493) |
| naproxen (CHEBI:7476) has role antirheumatic drug (CHEBI:35842) |
| naproxen (CHEBI:7476) has role antiviral agent (CHEBI:22587) |
| naproxen (CHEBI:7476) has role cyclooxygenase 1 inhibitor (CHEBI:50630) |
| naproxen (CHEBI:7476) has role cyclooxygenase 2 inhibitor (CHEBI:50629) |
| naproxen (CHEBI:7476) has role drug allergen (CHEBI:88188) |
| naproxen (CHEBI:7476) has role environmental contaminant (CHEBI:78298) |
| naproxen (CHEBI:7476) has role gout suppressant (CHEBI:35845) |
| naproxen (CHEBI:7476) has role immunosuppressive agent (CHEBI:35705) |
| naproxen (CHEBI:7476) has role non-narcotic analgesic (CHEBI:35481) |
| naproxen (CHEBI:7476) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| naproxen (CHEBI:7476) has role vulnerary (CHEBI:73336) |
| naproxen (CHEBI:7476) has role xenobiotic (CHEBI:35703) |
| naproxen (CHEBI:7476) is a methoxynaphthalene (CHEBI:48851) |
| naproxen (CHEBI:7476) is a monocarboxylic acid (CHEBI:25384) |
| naproxen (CHEBI:7476) is a naphthalenes (CHEBI:25477) |
| naproxen (CHEBI:7476) is a organic molecular entity (CHEBI:50860) |
| naproxen (CHEBI:7476) is conjugate acid of naproxen(1−) (CHEBI:59527) |
| Incoming Relation(s) |
| desmethylnaproxen sulfate (CHEBI:133458) has functional parent naproxen (CHEBI:7476) |
| naproxcinod (CHEBI:76254) has functional parent naproxen (CHEBI:7476) |
| naproxen(1−) (CHEBI:59527) is conjugate base of naproxen (CHEBI:7476) |
| IUPAC Name |
|---|
| (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid |
| INNs | Source |
|---|---|
| naproxen | DrugBank |
| naproxene | ChemIDplus |
| naproxeno | ChemIDplus |
| naproxenum | ChemIDplus |
| Synonyms | Source |
|---|---|
| (+)-2-(6-Methoxy-2-naphthyl)propionic acid | ChemIDplus |
| (+)-2-(Methoxy-2-naphthyl)-propionic acid | ChemIDplus |
| (+)-2-(Methoxy-2-naphthyl)-propionsäure | ChemIDplus |
| (+)-(S)-6-Methoxy-α-methyl-2-naphthaleneacetic acid | ChemIDplus |
| naproxen | ChEMBL |
| (+)-Naproxen | ChemIDplus |
| Brand Names | Source |
|---|---|
| Arthrosin 250 | ChEMBL |
| Arthrosin 250 ec | ChEMBL |
| Arthrosin 500 | ChEMBL |
| Arthrosin 500 ec | ChEMBL |
| Condrotec | ChEMBL |
| Feminax ultra | ChEMBL |
| Registry Numbers | Sources |
|---|---|
| Beilstein:3591067 | Beilstein |
| CAS:22204-53-1 | ChemIDplus |
| CAS:22204-53-1 | KEGG COMPOUND |
| Citations |
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