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CHEBI:70727 - topoisomerase inhibitor

ChEBI IDCHEBI:70727
ChEBI Nametopoisomerase inhibitor
Stars
DefinitionAn EC 5.99.1.* (miscellaneous isomerase) inhibitor that interferes with the action of any of the topoisomerases (enzymes that regulate the overwinding or underwinding of DNA).
Last Modified16 July 2020
SubmitterGareth Owen
Wikipedia
ChEBI Ontology
Outgoing Relation(s)
topoisomerase inhibitor (CHEBI:70727) is a EC 5.99.1.* (miscellaneous isomerase) inhibitor (CHEBI:76830)
Incoming Relation(s)
2,2,3,3-tetrahydroxy-2,3-dihydronaphthalene-1,4-dione (CHEBI:78857) has role topoisomerase inhibitor (CHEBI:70727)
actinodaphnine (CHEBI:2444) has role topoisomerase inhibitor (CHEBI:70727)
CP-115953 (CHEBI:232313) is a topoisomerase inhibitor (CHEBI:70727)
EC 5.99.1.2 (DNA topoisomerase) inhibitor (CHEBI:50276) is a topoisomerase inhibitor (CHEBI:70727)
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor (CHEBI:50750) is a topoisomerase inhibitor (CHEBI:70727)
topoisomerase II inhibitor (CHEBI:156203) is a topoisomerase inhibitor (CHEBI:70727)
topoisomerase IV inhibitor (CHEBI:53559) is a topoisomerase inhibitor (CHEBI:70727)
Synonym  Source
topoisomerase inhibitorsChEBI
Manual XrefsDatabases
TopoisomeraseWikipedia