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CHEBI:46195 - paracetamol
| Formula | C8H9NO2 |
| Net Charge | 0 |
| Average Mass | 151.165 |
| Monoisotopic Mass | 151.06333 |
| SMILES | CC(=O)Nc1ccc(O)cc1 |
| InChI | InChI=1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10) |
| InChIKey | RZVAJINKPMORJF-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Homo sapiens (ncbitaxon:9606) | blood serum (BTO:0000133) | MetaboLights (MTBLS90) |
| Roles Classification |
|---|
| Chemical Role: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. |
| Biological Roles: | anti-HBV agent An antiviral agent that destroys or inhibits the replication of the hepatitis B virus. human blood serum metabolite Any metabolite (endogenous or exogenous) found in human blood serum samples. antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. cyclooxygenase 3 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 3. ferroptosis inducer Any substance that induces or promotes ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. antiviral agent A substance that destroys or inhibits replication of viruses. anti-obesity agent Any substance which is used to reduce or control weight. xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. cyclooxygenase 1 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. hepatotoxic agent A role played by a chemical compound exhibiting itself through the ability to induce damage to the liver in animals. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. cyclooxygenase 2 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2. anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antiglaucoma drug Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye. vulnerary A drug used in treating and healing of wounds. renoprotective agent Any compound that is able to prevent damage to the kidneys. anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. antiparkinson drug A drug used in the treatment of Parkinson's disease. ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. hypoglycemic agent A drug which lowers the blood glucose level. anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. antiemetic A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors. antipyretic A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. antirheumatic drug A drug used to treat rheumatoid arthritis. anti-inflammatory agent Any compound that has anti-inflammatory effects. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. geroprotector Any compound that supports healthy aging, slows the biological aging process, or extends lifespan. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| paracetamol (CHEBI:46195) has functional parent 4-aminophenol (CHEBI:17602) |
| paracetamol (CHEBI:46195) has role analgesic (CHEBI:35480) |
| paracetamol (CHEBI:46195) has role anti-arrhythmia drug (CHEBI:38070) |
| paracetamol (CHEBI:46195) has role anti-HBV agent (CHEBI:64951) |
| paracetamol (CHEBI:46195) has role anti-HIV agent (CHEBI:64946) |
| paracetamol (CHEBI:46195) has role anti-inflammatory agent (CHEBI:67079) |
| paracetamol (CHEBI:46195) has role anti-obesity agent (CHEBI:74518) |
| paracetamol (CHEBI:46195) has role antibacterial agent (CHEBI:33282) |
| paracetamol (CHEBI:46195) has role antiemetic (CHEBI:50919) |
| paracetamol (CHEBI:46195) has role antiglaucoma drug (CHEBI:39456) |
| paracetamol (CHEBI:46195) has role antihypertensive agent (CHEBI:35674) |
| paracetamol (CHEBI:46195) has role antiinfective agent (CHEBI:35441) |
| paracetamol (CHEBI:46195) has role antimalarial (CHEBI:38068) |
| paracetamol (CHEBI:46195) has role antineoplastic agent (CHEBI:35610) |
| paracetamol (CHEBI:46195) has role antiparkinson drug (CHEBI:48407) |
| paracetamol (CHEBI:46195) has role antipyretic (CHEBI:35493) |
| paracetamol (CHEBI:46195) has role antirheumatic drug (CHEBI:35842) |
| paracetamol (CHEBI:46195) has role antiviral agent (CHEBI:22587) |
| paracetamol (CHEBI:46195) has role anxiolytic drug (CHEBI:35474) |
| paracetamol (CHEBI:46195) has role cyclooxygenase 1 inhibitor (CHEBI:50630) |
| paracetamol (CHEBI:46195) has role cyclooxygenase 2 inhibitor (CHEBI:50629) |
| paracetamol (CHEBI:46195) has role cyclooxygenase 3 inhibitor (CHEBI:73263) |
| paracetamol (CHEBI:46195) has role environmental contaminant (CHEBI:78298) |
| paracetamol (CHEBI:46195) has role ferroptosis inducer (CHEBI:173085) |
| paracetamol (CHEBI:46195) has role geroprotector (CHEBI:176497) |
| paracetamol (CHEBI:46195) has role hepatotoxic agent (CHEBI:50908) |
| paracetamol (CHEBI:46195) has role human blood serum metabolite (CHEBI:85234) |
| paracetamol (CHEBI:46195) has role hypoglycemic agent (CHEBI:35526) |
| paracetamol (CHEBI:46195) has role immunosuppressive agent (CHEBI:35705) |
| paracetamol (CHEBI:46195) has role neuroprotective agent (CHEBI:63726) |
| paracetamol (CHEBI:46195) has role non-narcotic analgesic (CHEBI:35481) |
| paracetamol (CHEBI:46195) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| paracetamol (CHEBI:46195) has role ophthalmology drug (CHEBI:66981) |
| paracetamol (CHEBI:46195) has role renoprotective agent (CHEBI:231911) |
| paracetamol (CHEBI:46195) has role vulnerary (CHEBI:73336) |
| paracetamol (CHEBI:46195) has role xenobiotic (CHEBI:35703) |
| paracetamol (CHEBI:46195) is a acetamides (CHEBI:22160) |
| paracetamol (CHEBI:46195) is a phenols (CHEBI:33853) |
| Incoming Relation(s) |
| S-(5-acetamido-2-hydroxyphenyl)-N-acetyl-L-cysteine (CHEBI:133435) has functional parent paracetamol (CHEBI:46195) |
| S-(5-acetamido-2-hydroxyphenyl)cysteine (CHEBI:133066) has functional parent paracetamol (CHEBI:46195) |
| 2-methoxyacetaminophen glucuronide (CHEBI:133005) has functional parent paracetamol (CHEBI:46195) |
| 3-nitroacetaminophen (CHEBI:139475) has functional parent paracetamol (CHEBI:46195) |
| 3-nitroacetaminophen-TMS (CHEBI:139476) has functional parent paracetamol (CHEBI:46195) |
| acetaminophen O-β-D-glucosiduronic acid (CHEBI:32636) has functional parent paracetamol (CHEBI:46195) |
| acetaminophen glutathione conjugate (CHEBI:32639) has functional parent paracetamol (CHEBI:46195) |
| methacetin (CHEBI:139354) has functional parent paracetamol (CHEBI:46195) |
| paracetamol sulfate (CHEBI:32635) has functional parent paracetamol (CHEBI:46195) |
| phenacetin (CHEBI:8050) has functional parent paracetamol (CHEBI:46195) |
| IUPAC Name |
|---|
| N-(4-hydroxyphenyl)acetamide |
| INNs | Source |
|---|---|
| paracetamol | KEGG DRUG |
| paracetamol | WHO MedNet |
| paracétamol | WHO MedNet |
| paracetamolum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 4-acetamidophenol | NIST Chemistry WebBook |
| 4-(Acetylamino)phenol | ChemIDplus |
| 4'-hydroxyacetanilide | ChemIDplus |
| Acenol | ChemIDplus |
| Acetaminofen | ChemIDplus |
| acetaminofén | ChemIDplus |
| Brand Names | Source |
|---|---|
| Abdine | ChEMBL |
| Acetaminophen component of allay | ChEMBL |
| Acetaminophen component of anexsia | ChEMBL |
| Acetaminophen component of anoquan | ChEMBL |
| Acetaminophen component of apadaz | ChEMBL |
| Acetaminophen component of bancap | ChEMBL |
| UniProt Name | Source |
|---|---|
| 4-acetamidophenol | UniProt |
| Manual Xrefs | Databases |
|---|---|
| 1906 | ChemSpider |
| 52 | DrugCentral |
| Acetaminophen | Wikipedia |
| C06804 | KEGG COMPOUND |
| CPD-7669 | MetaCyc |
| D00217 | KEGG DRUG |
| DB00316 | DrugBank |
| HMDB0001859 | HMDB |
| LSM-5533 | LINCS |
| TYL | PDBeChem |
| Citations |
|---|