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CHEBI:17276 - phloretin

ChEBI IDCHEBI:17276
ChEBI Namephloretin
Stars
DefinitionA member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 4, 2', 4' and 6'.
Secondary ChEBI IDsCHEBI:8111, CHEBI:14787, CHEBI:26014, CHEBI:42649
Last Modified21 January 2020
DownloadsMolfile
FormulaC15H14O5
Net Charge0
Average Mass274.272
Monoisotopic Mass274.08412
SMILESO=C(CCc1ccc(O)cc1)c1c(O)cc(O)cc1O
InChIInChI=1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2
InChIKeyVGEREEWJJVICBM-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
plant metabolite  Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
phloretin (CHEBI:17276) has functional parent dihydrochalcone (CHEBI:71231)
phloretin (CHEBI:17276) has role antineoplastic agent (CHEBI:35610)
phloretin (CHEBI:17276) has role plant metabolite (CHEBI:76924)
phloretin (CHEBI:17276) is a dihydrochalcones (CHEBI:71230)
Incoming Relation(s)
3-hydroxyphloretin 2'-O-xylosylglucoside (CHEBI:88354) has functional parent phloretin (CHEBI:17276)
asebogenin (CHEBI:2871) has functional parent phloretin (CHEBI:17276)
glycyphyllin (CHEBI:27400) has functional parent phloretin (CHEBI:17276)
phlorizin (CHEBI:8113) has functional parent phloretin (CHEBI:17276)
trilobatin (CHEBI:145829) has functional parent phloretin (CHEBI:17276)
IUPAC Name 
3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one
Synonyms  Source
PhloretinKEGG COMPOUND
3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanoneChEBI
UniProt Name  Source
phloretinUniProt
Manual XrefsDatabases
C00774KEGG COMPOUND
C00774KEGG COMPOUND
G50PDBeChem
LMPK12120525LIPID MAPS
DB07810DrugBank
PHLORETINMetaCyc
PhloretinWikipedia
HMDB0003306HMDB
CN103230408Patent
CN102701938Patent
C00007936KNApSAcK
LSM-6221LINCS
Registry NumbersSources
Reaxys:1887240Reaxys
CAS:60-82-2KEGG COMPOUND
CAS:60-82-2ChemIDplus
Citations