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CHEBI:15544 - prostaglandin E1

Default Structure
ChEBI IDCHEBI:15544
ChEBI Nameprostaglandin E1
Stars
ASCII Nameprostaglandin E1
Secondary ChEBI IDsCHEBI:142, CHEBI:10820, CHEBI:26322
Last Modified26 June 2017
SubmitterMarcus Ennis
DownloadsMolfile
FormulaC20H34O5
Net Charge0
Average Mass354.487
Monoisotopic Mass354.24062
SMILESCCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O
InChIInChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1
InChIKeyGMVPRGQOIOIIMI-DWKJAMRDSA-N
Wikipedia
Roles Classification
Biological Roles:
antiviral agent  A substance that destroys or inhibits replication of viruses.
human metabolite  Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
Applications:
vasodilator agent  A drug used to cause dilation of the blood vessels.
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
anticoagulant  An agent that prevents blood clotting.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
platelet aggregation inhibitor  A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
renoprotective agent  Any compound that is able to prevent damage to the kidneys.
ophthalmology drug  Any compound used for the treatment of eye conditions or eye diseases.
ChEBI Ontology
Outgoing Relation(s)
prostaglandin E1 (CHEBI:15544) has role anticoagulant (CHEBI:50249)
prostaglandin E1 (CHEBI:15544) has role antineoplastic agent (CHEBI:35610)
prostaglandin E1 (CHEBI:15544) has role antiviral agent (CHEBI:22587)
prostaglandin E1 (CHEBI:15544) has role cardiovascular drug (CHEBI:35554)
prostaglandin E1 (CHEBI:15544) has role human metabolite (CHEBI:77746)
prostaglandin E1 (CHEBI:15544) has role ophthalmology drug (CHEBI:66981)
prostaglandin E1 (CHEBI:15544) has role platelet aggregation inhibitor (CHEBI:50427)
prostaglandin E1 (CHEBI:15544) has role renoprotective agent (CHEBI:231911)
prostaglandin E1 (CHEBI:15544) has role vasodilator agent (CHEBI:35620)
prostaglandin E1 (CHEBI:15544) is a organic molecular entity (CHEBI:50860)
prostaglandin E1 (CHEBI:15544) is a prostaglandins E (CHEBI:26338)
prostaglandin E1 (CHEBI:15544) is a prostanoid (CHEBI:26347)
prostaglandin E1 (CHEBI:15544) is conjugate acid of prostaglandin E1(1−) (CHEBI:57397)
Incoming Relation(s)
13,14-dihydro-15-oxoprostaglandin E1 (CHEBI:134499) has functional parent prostaglandin E1 (CHEBI:15544)
15-dehydro-prostaglandin E1 (CHEBI:15548) has functional parent prostaglandin E1 (CHEBI:15544)
20-hydroxyprostaglandin E1 (CHEBI:137526) has functional parent prostaglandin E1 (CHEBI:15544)
6-oxoprostaglandin E1 (CHEBI:28269) has functional parent prostaglandin E1 (CHEBI:15544)
prostaglandin E1(1−) (CHEBI:57397) is conjugate base of prostaglandin E1 (CHEBI:15544)
IUPAC Name 
(13E,15S)-11α,15-dihydroxy-9-oxoprost-13-en-1-oic acid
INNs  Source
alprostadilKEGG DRUG
alprostadilWHO MedNet
alprostadilumChemIDplus
Synonyms  Source
(11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acidChemIDplus
11α,15α-dihydroxy-9-oxo-13-trans-prostenoic acidChemIDplus
(13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoateKEGG COMPOUND
(13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoateKEGG COMPOUND
alprostadilChEMBL
AlprostadilKEGG COMPOUND
Brand Names  Source
BefarKEGG DRUG
CaverjectDrugBank
Caverject impulseChEMBL
EdexDrugBank
MuseDrugBank
Prostin VRDrugBank
Manual XrefsDatabases
138DrugCentral
C04741KEGG COMPOUND
D00180KEGG DRUG
DB00770DrugBank
HMDB0001442HMDB
LMFA03010134LIPID MAPS
Prostaglandin_E1Wikipedia
Registry NumbersSources
Reaxys:2061617Reaxys
CAS:745-65-3KEGG COMPOUND
CAS:745-65-3ChemIDplus
Citations