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CHEBI:15544 - prostaglandin E1

Default Structure
ChEBI IDCHEBI:15544
ChEBI Nameprostaglandin E1
Stars
ASCII Nameprostaglandin E1
Secondary ChEBI IDsCHEBI:142, CHEBI:10820, CHEBI:26322
Last Modified26 June 2017
SubmitterMarcus Ennis
DownloadsMolfile
FormulaC20H34O5
Net Charge0
Average Mass354.487
Monoisotopic Mass354.24062
SMILESCCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O
InChIInChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1
InChIKeyGMVPRGQOIOIIMI-DWKJAMRDSA-N
Wikipedia
Roles Classification
Biological Roles:
human metabolite  Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
antiviral agent  A substance that destroys or inhibits replication of viruses.
Applications:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
renoprotective agent  Any compound that is able to prevent damage to the kidneys.
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
platelet aggregation inhibitor  A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
ophthalmology drug  Any compound used for the treatment of eye conditions or eye diseases.
anticoagulant  An agent that prevents blood clotting.
vasodilator agent  A drug used to cause dilation of the blood vessels.
ChEBI Ontology
Outgoing Relation(s)
prostaglandin E1 (CHEBI:15544) has role anticoagulant (CHEBI:50249)
prostaglandin E1 (CHEBI:15544) has role antineoplastic agent (CHEBI:35610)
prostaglandin E1 (CHEBI:15544) has role antiviral agent (CHEBI:22587)
prostaglandin E1 (CHEBI:15544) has role cardiovascular drug (CHEBI:35554)
prostaglandin E1 (CHEBI:15544) has role human metabolite (CHEBI:77746)
prostaglandin E1 (CHEBI:15544) has role ophthalmology drug (CHEBI:66981)
prostaglandin E1 (CHEBI:15544) has role platelet aggregation inhibitor (CHEBI:50427)
prostaglandin E1 (CHEBI:15544) has role renoprotective agent (CHEBI:231911)
prostaglandin E1 (CHEBI:15544) has role vasodilator agent (CHEBI:35620)
prostaglandin E1 (CHEBI:15544) is a prostaglandins E (CHEBI:26338)
prostaglandin E1 (CHEBI:15544) is conjugate acid of prostaglandin E1(1−) (CHEBI:57397)
Incoming Relation(s)
13,14-dihydro-15-oxoprostaglandin E1 (CHEBI:134499) has functional parent prostaglandin E1 (CHEBI:15544)
15-dehydro-prostaglandin E1 (CHEBI:15548) has functional parent prostaglandin E1 (CHEBI:15544)
20-hydroxyprostaglandin E1 (CHEBI:137526) has functional parent prostaglandin E1 (CHEBI:15544)
6-oxoprostaglandin E1 (CHEBI:28269) has functional parent prostaglandin E1 (CHEBI:15544)
prostaglandin E1(1−) (CHEBI:57397) is conjugate base of prostaglandin E1 (CHEBI:15544)
IUPAC Name 
(13E,15S)-11α,15-dihydroxy-9-oxoprost-13-en-1-oic acid
INNs  Source
alprostadilKEGG DRUG
alprostadilWHO MedNet
alprostadilumChemIDplus
Synonyms  Source
(11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acidChemIDplus
11α,15α-dihydroxy-9-oxo-13-trans-prostenoic acidChemIDplus
(13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoateKEGG COMPOUND
(13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoateKEGG COMPOUND
alprostadilChEMBL
AlprostadilKEGG COMPOUND
Brand Names  Source
BefarKEGG DRUG
CaverjectDrugBank
Caverject impulseChEMBL
EdexDrugBank
MuseDrugBank
Prostin VRDrugBank
Manual XrefsDatabases
138DrugCentral
C04741KEGG COMPOUND
D00180KEGG DRUG
DB00770DrugBank
HMDB0001442HMDB
LMFA03010134LIPID MAPS
Prostaglandin_E1Wikipedia
Registry NumbersSources
Reaxys:2061617Reaxys
CAS:745-65-3KEGG COMPOUND
CAS:745-65-3ChemIDplus
Citations