Ligand clusters for UniProt code P09960

Ligand clusters for P09960: Leukotriene A-4 hydrolase from Homo sapiens

		Top 6 (of 21) ligand clusters Cluster 1. 57 ligand types 148 ligands Cluster 2. 3 ligand types 3 ligands Cluster 3. 2 ligand types 52 ligands Cluster 4. 3 ligand types 6 ligands Cluster 5. 2 ligand types 2 ligands Cluster 6. 3 ligand types 80 ligands
Representative protein: 1gw6A

Structures

PDB		Schematic diagram
1gw6A
3b7sA
3fu3A
6endA
3b7tA
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Cluster 1 contains 57 ligand types (of which only 20 are listed. Click for all)

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Ligand		Description
_Zn		1. Metal: _ZN × 65 PDB codes: 1gw6(A), 1h19(A), 1hs6(A), 1sqm(A), 2r59(A), 2vj8(A), 3b7r(L), 3b7s(A), 3b7t(A), 3b7u(X), 3cho(A), 3chp(A), 3chq(A), 3chr(A), 3fh5(A), 3fh7(A), 3fh8(A), 3fhe(A), 3fts(A), 3ftu(A), 3ftv(A), 3ftw(A), 3ftx(A), 3fty(A), 3ftz(A), 3fu0(A), 3fu3(A), 3fu5(A), 3fu6(A), 3fud(A), 3fue(A), 3fuf(A), 3fuh(A), 3fui(A), 3fuj(A), 3fuk(A), 3ful(A), 3fum(A), 3fun(A), 3u9w(A), 4dpr(A), 4l2l(A), 4mkt(A), 4ms6(A), 4r7l(A), 4rsy(A), 4rvb(A), 5aen(A), 5bpp(A), 5fwq(A), 5n3w(A), 5ni2(A), 5ni4(A), 5ni6(A), 5nia(A), 5nid(A), 5nie(A), 6enb(A), 6enc(A), 6end(A), 6o5h(A), 7auz(A), 7av0(A), 7av1(A), 7av2(A).
		2. Ligand: ACY × 3 acetic acid Acetic acid PDB codes: 1h19(A), 1sqm(A), 5ni6(A).
		3. Ligand: GOL × 2 glycerin Glycerol PDB codes: 4r7l(A),
		4. Ligand: A4Z × 1 bufexamac 2-(4-Butoxyphenyl)-N-Hydroxyacetamide PDB code: 5bpp(A).
		5. Ligand: SHH × 1 vorinostat Octanedioic acid hydroxyamide phenylamide PDB code: 4r7l(A).
		6. Ligand: X8Z × 1 captopril L-Captopril PDB code: 4dpr(A).
		7. Ligand: ACT × 1 Acetate ion PDB code: 1gw6(A).
		8. Ligand: BES × 2 2-(3-Amino-2-Hydroxy-4-Phenyl-Butyrylamino)-4-Methyl- Pentanoic acid PDB codes: 1gw6(A), 1hs6(A).
		9. Ligand: ACT × 12 Acetate ion PDB codes: 3ftw(A), 3fty(A), 3ftz(A), 3fu0(A), 3fu3(A), 3fu6(A), 4l2l(A), 4r7l(A), 4rvb(A), 5fwq(A), 5n3w(A).
		10. Ligand: BES × 4 2-(3-Amino-2-Hydroxy-4-Phenyl-Butyrylamino)-4-Methyl- Pentanoic acid PDB codes: 3ftx(A), 3fue(A), 3fuf(A), 3fuh(A).
		11. Ligand: DJ3 × 3 5s-5,6-Oxido-7,9-Trans-11,14-Cis-Eicosatetraenoic acid PDB codes: 5ni2(A), 5ni4(A), 5ni6(A).
		12. Ligand: IMD × 3 Imidazole PDB codes: 4rvb(A), 5fwq(A),
		13. Ligand: 11X × 2 N-(Pyridin-3-Ylmethyl)aniline PDB codes: 3ftv(A), 3ftw(A).
		14. Ligand: 1V6 × 2 4-(4-Benzylphenyl)-1,3-Thiazol-2-Amine PDB codes: 4l2l(A), 4mkt(A).
		15. Ligand: 28P × 2 N-[3-(4-Benzylphenoxy)propyl]-N-Methyl-Beta-Alanine PDB codes: 3fhe(A), 3u9w(A).
		16. Ligand: 28T × 2 1-{4-Oxo-4-[(2s)-Pyrrolidin-2-Yl]butanoyl}-L-Proline PDB codes: 4mkt(A), 4ms6(A).
		17. Ligand: RE2 × 2 5-[2-(4-Hydroxyphenyl)ethyl]benzene-1,3-Diol PDB codes: 3ftu(A), 3ftx(A).
		18. Ligand: 00G × 1 5-[2-(1h-Pyrrol-1-Yl)ethoxy]-1h-Indole PDB code: 3fuj(A).
		19. Ligand: 11S × 1 5-Chloro-1h-Indole PDB code: 3fue(A).
		20. Ligand: 14O × 1 5-Fluoro-1h-Indole PDB code: 3fuf(A).
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Cluster 2 contains 3 ligand types

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Ligand		Description
		1. Ligand: 692 × 1 N-Methyl-1-(2-Thiophen-2-Ylphenyl)methanamine PDB code: 3fud(A).
		2. Ligand: IMD × 1 Imidazole PDB code: 3u9w(A).
_Yb		3. Metal: _YB × 1 PDB code: 3u9w(A).

Cluster 3 contains 2 ligand types

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Ligand		Description
		1. Ligand: IMD × 51 Imidazole PDB codes: 1gw6(A), 1h19(A), 1hs6(A), 1sqm(A), 2vj8(A), 3b7r(L), 3b7t(A), 3b7u(X), 3chp(A), 3chq(A), 3chr(A), 3fh5(A), 3fh7(A), 3fh8(A), 3fhe(A), 3fts(A), 3ftu(A), 3ftv(A), 3ftw(A), 3ftx(A), 3fty(A), 3ftz(A), 3fu0(A), 3fu3(A), 3fu5(A), 3fu6(A), 3fud(A), 3fue(A), 3fuf(A), 3fuh(A), 3fui(A), 3fuj(A), 3fuk(A), 3ful(A), 3fum(A), 3fun(A), 3u9w(A), 4r7l(A), 4rsy(A), 4rvb(A), 5aen(A), 5fwq(A), 5n3w(A), 5ni4(A), 6enb(A), 6enc(A), 6end(A), 7auz(A), 7av0(A), 7av1(A), 7av2(A).
		2. Ligand: 92G × 1 4-(2-Amino-1,3-Thiazol-4-Yl)phenol PDB code: 3fu3(A).

Cluster 4 contains 3 ligand types

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Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 4rvb(A).
_Yb		2. Metal: _YB × 4 PDB codes: 4l2l(A), 5aen(A), 5fwq(A), 5ni2(A).
		3. Ligand: IMD × 1 Imidazole PDB code: 5ni4(A).

Cluster 5 contains 2 ligand types

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Ligand		Description
		1. Ligand: ACY × 1 acetic acid Acetic acid PDB code: 4rvb(A).
		2. Ligand: GOL × 1 glycerin Glycerol PDB code: 4dpr(A).

Cluster 6 contains 3 ligand types

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Ligand		Description
		1. Ligand: ACY × 4 acetic acid Acetic acid PDB codes: 3b7s(A), 3b7u(X), 4mkt(A), 4ms6(A).
_Yb		2. Metal: _YB × 48 PDB codes: 1gw6(A), 1h19(A), 1hs6(A), 2r59(A), 2vj8(A), 3b7r(L), 3b7s(A), 3b7t(A), 3b7u(X), 3cho(A), 3chp(A), 3chq(A), 3chr(A), 3fh5(A), 3fh7(A), 3fh8(A), 3fhe(A), 3fts(A), 3ftu(A), 3ftv(A), 3ftw(A), 3ftx(A), 3fty(A), 3ftz(A), 3fu0(A), 3fu3(A), 3fu5(A), 3fu6(A), 3fud(A), 3fue(A), 3fuf(A), 3fuh(A), 3fuj(A), 3fuk(A), 3fum(A), 3fun(A), 3u9w(A), 4dpr(A), 4l2l(A), 4mkt(A), 4ms6(A), 4rvb(A), 5aen(A), 5fwq(A), 5n3w(A), 6enb(A), 6enc(A), 6end(A).
		3. Ligand: ACT × 28 Acetate ion PDB codes: 3cho(A), 3chp(A), 3fh5(A), 3fh7(A), 3fh8(A), 3fhe(A), 3fts(A), 3ftu(A), 3ftw(A), 3ftx(A), 3fty(A), 3ftz(A), 3fu3(A), 3fu5(A), 3fu6(A), 3fud(A), 3fuj(A), 3fum(A), 3fun(A), 3u9w(A), 4rvb(A), 6enb(A), 6enc(A), 6end(A), 7auz(A), 7av0(A), 7av1(A), 7av2(A).