› 2amx

X-ray diffraction
2.02Å resolution

Function and Biology Details

Reaction catalysed: 
2'-deoxyadenosine + H(2)O = 2'-deoxyinosine + NH(3)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181892 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenosine deaminase Chains: A, B
Molecule details ›
Chains: A, B
Length: 376 amino acids
Theoretical weight: 43.34 KDa
Source organism: Plasmodium yoelii
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q7RMV2 (Residues: 8-364; Coverage: 98%)
Gene name: PY02076
Sequence domains: Adenosine deaminase
Structure domains: Metal-dependent hydrolases

Ligands and Environments

2 bound ligands:
Ligand CO 5 x CO
Ligand UNX 6 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E, null
Spacegroup: P212121
Unit cell:
a: 66.719Å b: 90.332Å c: 137.086Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.196 0.246
Expression system: Escherichia coli BL21

Quick links

Citations

34 review citations

Structure-based insights into the catalytic power and conformational dexterity of peroxiredoxins.
Hall et al. (2011)
33 more

5 mentions without citation

Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination.
Vedadi et al. (2006)
4 more