Active Site

Adenosine/AMP deaminase active site (IPR006650)

Short name: A/AMP_deam_AS

Description

Adenosine deaminase (EC:3.5.4.4) catalyzes the hydrolytic deamination of adenosine into inosine and AMP deaminase (EC:3.5.4.6) catalyzes the hydrolytic deamination of AMP into IMP. It has been shown [PMID: 1998686] that these two enzymes share three regions of sequence similarities; these regions are centred on residues which are proposed to play an important role in the catalytic mechanism of these two enzymes. This entry presents one of these regions, it contains two conserved aspartic acid residues that are potential active site residues.

GO terms

Biological Process

GO:0009168 purine ribonucleoside monophosphate biosynthetic process

Molecular Function

GO:0019239 deaminase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns