Domain

Adenosine/AMP deaminase domain (IPR001365)

Short name: A/AMP_deaminase_dom

Domain relationships

None.

Description

Adenosine deaminase (EC:3.5.4.4) catalyzes the hydrolytic deamination of adenosine into inosine and AMP deaminase (EC:3.5.4.6) catalyzes the hydrolytic deamination of AMP into IMP. It has been shown [PMID: 1998686] that these two enzymes share three regions of sequence similarities; these regions are centred on residues which are proposed to play an important role in the catalytic mechanism of these two enzymes.

This entry represents the main structural domain of adenosine deaminase and AMP deaminase proteins.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0019239 deaminase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam