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Structure of P.furiosus Argonaute with bound Mn2+

X-ray diffraction
2.7Å resolution
PDB entry 1z25 coloured by chain, front view.
PDB entry 1z25 coloured by chain, side view.
PDB entry 1z25 coloured by chain, top view.
Source organism: Pyrococcus furiosus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Protein argonaute
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Multimeric state: monomeric
Accessible surface area: 34687.76 Å2
Buried surface area: 124.66 Å2
Dissociation area: 62.33 Å2
Dissociation energy (ΔGdiss): 5.18 kcal/mol
Dissociation entropy (TΔSdiss): -0.13 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-186456

Macromolecules

Protein argonaute
Chain: A
Length: 771 amino acids
Theoretical weight: 90.6 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8U3D2 (Residues: 1-770; Coverage: 100%)
Gene names: PF0537, ago
Pfam:
InterPro:
CATH:
SCOP:
Protein argonaute in PDB entry 1z25, assembly 1, front view.
Protein argonaute in PDB entry 1z25, assembly 1, side view.
Protein argonaute in PDB entry 1z25, assembly 1, top view.
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