4elv Summary

pdbe.org/4elv
spacer

Snapshot of the large fragment of DNA polymerase I from Thermus Aquaticus processing modified pyrimidines

A publication describing this structure is not available. The depositing authors are Marx, A.search; Diederichs, K.search; Obeid, S.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.9 Å and deposited in 2012.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 3 biomacromolecules, namely DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(0R8))-3'), and DNA (5'-D(*AP*AP*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3').

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A DNA polymerase I, thermostable P19821 (293-832) (DPO1_THEAQ)search Thermus aquaticussearch 100% 540 99%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P19821 (293 - 832) DNA polymerase I, thermostable Thermus aquaticus

Chain Sequence family (Pfam)
A (P19821) PF00476: DNA polymerase family Asearch, PF09281: Taq polymerase, exonucleasesearch

Chain ID Molecular function (GO) Biological process (GO)
A (P19821) nucleoside bindingsearch nucleic acid bindingsearch DNA bindingsearch DNA-directed DNA polymerase activitysearch DNA replicationsearch DNA-dependent DNA replicationsearch DNA repairsearch

Chain InterPro annotation
A DNA-directed DNA polymerase, family A, palm domainsearch DNA polymerase Asearch Ribonuclease H-like domainsearch Taq polymerase, thermostable, exonuclease regionsearch DNA polymerase 1search DNA-directed DNA polymerase, family A, conserved sitesearch