Structure analysis

Snapshot of the large fragment of DNA polymerase I from Thermus Aquaticus processing modified pyrimidines

X-ray diffraction
1.9Å resolution
Assembly composition:
hetero trimer (preferred)
Entry contents: 1 distinct polypeptide molecule
2 distinct DNA molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero trimer
Accessible surface area: 24900 Å2
Buried surface area: 8500 Å2
Dissociation area: 2,200 Å2
Dissociation energy (ΔGdiss): 17 kcal/mol
Dissociation entropy (TΔSdiss): 12 kcal/mol
Interface energy (ΔGint): -36 kcal/mol
Symmetry number: 1

Macromolecules

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Name: DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(0R8))-3')
Representative chains: B
Source organism: synthetic construct [32630]
Expression system: Not provided
Length: 12 nucleotides
Theoretical weight: 3.74 KDa

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Name: DNA (5'-D(*AP*AP*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3')
Representative chains: C
Source organism: synthetic construct [32630]
Expression system: Not provided
Length: 16 nucleotides
Theoretical weight: 4.96 KDa

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