Electron Microscopy Data Bank

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sample_name:"Ribosomal_L18_c domain-containing protein"

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EMD-19195

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Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-RAMP4

Release date: Jan. 24, 2024
Resolution: 2.69243 Å
EM Method: Single-particle
Fitted PDBs: 8rjb
Q-score: 0.608

Lewis AJO, Hegde RS

To Be Published

Sample:

Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
5.8s rrna (50 kDa, RNA from Oryctolagus cuniculus)
Ribosomal protein l32 (15 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l3 (46 kDa, Protein from Oryctolagus cuniculus)
Protein transport protein sec61 subunit gamma (7 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l36 (12 kDa, Protein from Oryctolagus cuniculus)
Zinc ion (65 Da, Ligand)
28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
60s ribosomal protein l35 (14 kDa, Protein from Oryctolagus cuniculus)
P-site trna (24 kDa, RNA from Sus scrofa)
Ribosomal protein l8 (28 kDa, Protein from Oryctolagus cuniculus)
Protein transport protein sec61 subunit alpha isoform 1 (52 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l31 (14 kDa, Protein from Oryctolagus cuniculus)
Ribosomal_l18_c domain-containing protein (34 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l26 (17 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l39-like (6 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l27a (16 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l11 (20 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l28 (15 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l14 (23 kDa, Protein from Oryctolagus cuniculus)
5s rrna (38 kDa, RNA from Oryctolagus cuniculus)
Ribosomal protein l22 (14 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l6 (33 kDa, Protein from Oryctolagus cuniculus)
Stress-associated endoplasmic reticulum protein (7 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l10 (24 kDa, Protein from Oryctolagus cuniculus)
Large ribosomal subunit protein el30 (12 kDa, Protein from Oryctolagus)
60s ribosomal protein l34 (13 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein ul30 (29 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l38 (8 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l13 (24 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l19 (23 kDa, Protein from Oryctolagus cuniculus)
80s ribosome translating a stalled, two-tmd nascent chain (derived from rhodopsin), and bound to sec61, the trap complex, and ramp4 (Complex from Canis lupus familiaris)
60s ribosomal protein l36a-like (12 kDa, Protein from Oryctolagus cuniculus)
Large ribosomal subunit protein ul4 (47 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l13 (23 kDa, Protein from Oryctolagus cuniculus)
Protein transport protein sec61 subunit beta (9 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l18a (20 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l29 (24 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l24 (17 kDa, Protein from Oryctolagus cuniculus)
El40 (11 kDa, Protein from Oryctolagus cuniculus)
Nascent chain (23 kDa, Protein from Bos taurus)
60s ribosomal protein l21 (18 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l7a (36 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l37a (10 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l26 (21 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l35a (12 kDa, Protein from Oryctolagus cuniculus)
Magnesium ion (24 Da, Ligand)
Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l23 (14 kDa, Protein from Oryctolagus cuniculus)
Ul22 (21 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l9 (21 kDa, Protein from Oryctolagus cuniculus)
Ribosomal_l23en domain-containing protein (17 kDa, Protein from Oryctolagus cuniculus)

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EMD-19197

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Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-TRAP, open conformation 1

Release date: Jan. 24, 2024
Resolution: 2.90061 Å
EM Method: Single-particle
Fitted PDBs: 8rjc
Q-score: 0.568

Lewis AJO, Hegde RS

To Be Published

Sample:

Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
5.8s rrna (50 kDa, RNA from Oryctolagus cuniculus)
Ribosomal protein l32 (15 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l3 (46 kDa, Protein from Oryctolagus cuniculus)
Protein transport protein sec61 subunit gamma (7 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l36 (12 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l30 (12 kDa, Protein from Oryctolagus cuniculus)
Zinc ion (65 Da, Ligand)
28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
60s ribosomal protein l35 (14 kDa, Protein from Oryctolagus cuniculus)
P-site trna (24 kDa, RNA from Sus scrofa)
Ribosomal protein l8 (28 kDa, Protein from Oryctolagus cuniculus)
Protein transport protein sec61 subunit alpha isoform 1 (52 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l31 (14 kDa, Protein from Oryctolagus cuniculus)
Ribosomal_l18_c domain-containing protein (34 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l26 (17 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l39-like (6 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l27a (16 kDa, Protein from Oryctolagus cuniculus)
Translocon-associated protein subunit beta (20 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l11 (20 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l18 (21 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l28 (15 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l14 (23 kDa, Protein from Oryctolagus cuniculus)
5s rrna (38 kDa, RNA from Oryctolagus cuniculus)
Ribosomal protein l22 (14 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l6 (33 kDa, Protein from Oryctolagus cuniculus)
Stress-associated endoplasmic reticulum protein (7 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l10 (24 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l34 (13 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein ul30 (29 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l38 (8 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l13 (24 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l19 (23 kDa, Protein from Oryctolagus cuniculus)
80s ribosome translating a stalled, two-tmd nascent chain (derived from rhodopsin), and bound to sec61, the trap complex, and ramp4 (Complex from Canis lupus familiaris)
60s ribosomal protein l36a-like (12 kDa, Protein from Oryctolagus cuniculus)
Large ribosomal subunit protein ul4 (47 kDa, Protein from Oryctolagus cuniculus)
Translocon-associated protein subunit gamma (21 kDa, Protein from Canis lupus familiaris)
Protein transport protein sec61 subunit beta (9 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l13 (23 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l18a (20 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l24 (17 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l29 (24 kDa, Protein from Oryctolagus cuniculus)
El40 (11 kDa, Protein from Oryctolagus cuniculus)
Nascent chain (23 kDa, Protein from Bos taurus)
60s ribosomal protein l21 (18 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l7a (36 kDa, Protein from Oryctolagus cuniculus)
Calnexin (67 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l35a (12 kDa, Protein from Oryctolagus cuniculus)
Magnesium ion (24 Da, Ligand)
60s ribosomal protein l37a (10 kDa, Protein from Oryctolagus)
Translocon-associated protein subunit alpha (32 kDa, Protein from Canis lupus familiaris)
Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l23 (14 kDa, Protein from Oryctolagus cuniculus)
Ul22 (21 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l9 (21 kDa, Protein from Oryctolagus cuniculus)
Ribosomal_l23en domain-containing protein (17 kDa, Protein from Oryctolagus cuniculus)
Translocon-associated protein subunit delta (18 kDa, Protein from Canis lupus familiaris)

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EMD-19198

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Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-TRAP, open conformation 2

Release date: Jan. 24, 2024
Resolution: 2.78574 Å
EM Method: Single-particle
Fitted PDBs: 8rjd

Lewis AJO, Hegde RS

To Be Published

Sample:

Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
5.8s rrna (50 kDa, RNA from Oryctolagus cuniculus)
Ribosomal protein l32 (15 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l3 (46 kDa, Protein from Oryctolagus cuniculus)
Protein transport protein sec61 subunit gamma (7 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l36 (12 kDa, Protein from Oryctolagus cuniculus)
Zinc ion (65 Da, Ligand)
28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
60s ribosomal protein l13a (23 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l35 (14 kDa, Protein from Oryctolagus cuniculus)
P-site trna (24 kDa, RNA from Sus scrofa)
Ribosomal protein l8 (28 kDa, Protein from Oryctolagus cuniculus)
Protein transport protein sec61 subunit alpha isoform 1 (52 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l31 (14 kDa, Protein from Oryctolagus cuniculus)
Ribosomal_l18_c domain-containing protein (34 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l39-like (6 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l27a (16 kDa, Protein from Oryctolagus cuniculus)
Translocon-associated protein subunit beta (20 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l11 (20 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l18 (21 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l28 (15 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l14 (23 kDa, Protein from Oryctolagus cuniculus)
Large ribosomal subunit protein el38 (8 kDa, Protein from Oryctolagus)
5s rrna (38 kDa, RNA from Oryctolagus cuniculus)
60s ribosomal protein l6 (33 kDa, Protein from Oryctolagus cuniculus)
Stress-associated endoplasmic reticulum protein (7 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l10 (24 kDa, Protein from Oryctolagus cuniculus)
Large ribosomal subunit protein el30 (12 kDa, Protein from Oryctolagus)
60s ribosomal protein l34 (13 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein ul30 (29 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l13 (24 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l19 (23 kDa, Protein from Oryctolagus cuniculus)
80s ribosome translating a stalled, two-tmd nascent chain (derived from rhodopsin), and bound to sec61, the trap complex, and ramp4 (Complex from Canis lupus familiaris)
60s ribosomal protein l36a-like (12 kDa, Protein from Oryctolagus cuniculus)
Large ribosomal subunit protein ul4 (47 kDa, Protein from Oryctolagus cuniculus)
Translocon-associated protein subunit gamma (21 kDa, Protein from Canis lupus familiaris)
Protein transport protein sec61 subunit beta (9 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l18a (20 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l29 (24 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l24 (17 kDa, Protein from Oryctolagus cuniculus)
El40 (11 kDa, Protein from Oryctolagus cuniculus)
Nascent chain (23 kDa, Protein from Bos taurus)
60s ribosomal protein l21 (18 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l7a (36 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l37a (10 kDa, Protein from Oryctolagus cuniculus)
Calnexin (67 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l35a (12 kDa, Protein from Oryctolagus cuniculus)
Magnesium ion (24 Da, Ligand)
Ribosomal protein l26 (17 kDa, Protein from Oryctolagus)
Translocon-associated protein subunit alpha (32 kDa, Protein from Canis lupus familiaris)
Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l23 (14 kDa, Protein from Oryctolagus cuniculus)
Ul22 (21 kDa, Protein from Oryctolagus cuniculus)
Large ribosomal subunit protein ul23 n-terminal domain-containing protein (17 kDa, Protein from Oryctolagus)
60s ribosomal protein l9 (21 kDa, Protein from Oryctolagus cuniculus)
Translocon-associated protein subunit delta (18 kDa, Protein from Canis lupus familiaris)
Large ribosomal subunit protein el22 (14 kDa, Protein from Oryctolagus cuniculus)

[Show more]

EMD-40344

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Terminating ribosome with SRI-41315

Release date: Dec. 27, 2023
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8scb
Q-score: 0.589

Coelho JPL, Yip MCJ, Oltion K, Taunton J, Shao S

To Be Published

Sample:

Atp binding cassette subfamily e member 1 (67 kDa, Protein from Oryctolagus cuniculus)
60s acidic ribosomal protein p0 (34 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l36 (12 kDa, Protein from Oryctolagus cuniculus)
Us4 (22 kDa, Protein from Oryctolagus cuniculus)
28s_rrna (1 MDa, RNA from Oryctolagus cuniculus)
Es31 (18 kDa, Protein from Oryctolagus cuniculus)
Us2 (sa) (32 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l27a (16 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s24 (15 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l29 (26 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l6 (33 kDa, Protein from Oryctolagus cuniculus)
5s_rrna (38 kDa, RNA from Oryctolagus cuniculus)
40s ribosomal protein s26 (13 kDa, Protein from Oryctolagus cuniculus)
Es25 (13 kDa, Protein from Oryctolagus cuniculus)
Us17 (18 kDa, Protein from Oryctolagus cuniculus)
Us8 (14 kDa, Protein from Oryctolagus cuniculus)
E_trna (24 kDa, RNA from Oryctolagus cuniculus)
Mrna (63 kDa, RNA from Homo sapiens)
Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
Ul22 (21 kDa, Protein from Oryctolagus cuniculus)
El21 (18 kDa, Protein from Oryctolagus cuniculus)
Us14 (6 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l3 (46 kDa, Protein from Oryctolagus cuniculus)
Es7 (22 kDa, Protein from Oryctolagus cuniculus)
Es28 (7 kDa, Protein from Oryctolagus cuniculus)
Es12 (14 kDa, Protein from Oryctolagus cuniculus)
Us11 (18 kDa, Protein from Oryctolagus cuniculus)
El41 (3 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l18 (21 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l8 (28 kDa, Protein from Oryctolagus cuniculus)
Es8 (24 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l11 (20 kDa, Protein from Oryctolagus cuniculus)
S10_plectin domain-containing protein (18 kDa, Protein from Oryctolagus cuniculus)
Es4 (s4 x isoform) (29 kDa, Protein from Oryctolagus cuniculus)
Us7 (22 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l34 (13 kDa, Protein from Oryctolagus cuniculus)
Us12 (15 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l23 (14 kDa, Protein from Oryctolagus cuniculus)
El32 (15 kDa, Protein from Oryctolagus cuniculus)
18s_rrna (603 kDa, RNA from Oryctolagus cuniculus)
Us19 (17 kDa, Protein from Oryctolagus cuniculus)
Eukaryotic peptide chain release factor subunit 1 (51 kDa, Protein from Homo sapiens)
Ul24 (17 kDa, Protein from Oryctolagus cuniculus)
Es19 (16 kDa, Protein from Oryctolagus cuniculus)
El42 (12 kDa, Protein from Oryctolagus cuniculus)
El28 (15 kDa, Protein from Oryctolagus cuniculus)
P_trna (24 kDa, RNA from Oryctolagus cuniculus)
Us13 (17 kDa, Protein from Oryctolagus cuniculus)
Es6 (28 kDa, Protein from Oryctolagus cuniculus)
Water (18 Da, Ligand)
El22 (14 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l14 (23 kDa, Protein from Oryctolagus cuniculus)
(2s,4as)-2-cyclobutyl-10-methyl-3-phenyl-2,10-dihydropyrimido[4,5-b]quinoline-4,5(3h,4ah)-dione (359 Da, Ligand)
60s ribosomal protein l10 (24 kDa, Protein from Oryctolagus cuniculus)
El31 (14 kDa, Protein from Oryctolagus cuniculus)
El35 (14 kDa, Protein from Oryctolagus cuniculus)
Nc (13 kDa, Protein from Homo sapiens)
El39 (6 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l19 (23 kDa, Protein from Oryctolagus cuniculus)
El33 (12 kDa, Protein from Oryctolagus cuniculus)
Ubiquitin a-52 residue ribosomal protein fusion product 1 (10 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l7a (36 kDa, Protein from Oryctolagus cuniculus)
El20 (20 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l12 (17 kDa, Protein from Oryctolagus cuniculus)
Ul13 (23 kDa, Protein from Oryctolagus cuniculus)
Terminating rabbit ribosome (4 MDa, Complex from Oryctolagus cuniculus)
Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
Es27 (9 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l4 (46 kDa, Protein from Oryctolagus cuniculus)
Es21 (9 kDa, Protein from Oryctolagus cuniculus)
El43 (10 kDa, Protein from Oryctolagus cuniculus)
Zinc ion (65 Da, Ligand)
Us15 (17 kDa, Protein from Oryctolagus cuniculus)
Es17 (15 kDa, Protein from Oryctolagus cuniculus)
El13 (24 kDa, Protein from Oryctolagus cuniculus)
Ribosomal_l18_c domain-containing protein (34 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l7 (29 kDa, Protein from Oryctolagus cuniculus)
Iron/sulfur cluster (351 Da, Ligand)
Es30 (14 kDa, Protein from Oryctolagus cuniculus)
El23 (17 kDa, Protein from Oryctolagus cuniculus)
Es1 (30 kDa, Protein from Oryctolagus cuniculus)
Us5 (31 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l38 (8 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l24 (17 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein s3 (26 kDa, Protein from Oryctolagus cuniculus)
Receptor for activated c kinase 1 (rack1) (35 kDa, Protein from Oryctolagus cuniculus)
Magnesium ion (24 Da, Ligand)
5.8s_rrna (50 kDa, RNA from Oryctolagus cuniculus)
60s ribosomal protein l9 (21 kDa, Protein from Oryctolagus cuniculus)
El30 (12 kDa, Protein from Oryctolagus cuniculus)
Us10 (13 kDa, Protein from Oryctolagus cuniculus)
Us9 (16 kDa, Protein from Oryctolagus cuniculus)

[Show more]

EMD-16155

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Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 (TTC5) and S-phase Cyclin A Associated Protein residing in the ER (SCAPER)

Release date: July 5, 2023
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8bpo
Q-score: 0.549

Hopfler M, Absmeier E, Peak-Chew SY, Vartholomaiou E, Passmore LA, Gasic I, Hegde RS

Mol Cell (2023) 83 pp. 2290- [ DOI: doi:10.1016/j.molcel.2023.05.020 Pubmed: 37295431 ]

Sample:

60s ribosomal protein l22 (14 kDa, Protein from rabbit)
Ribosomal protein l18 (21 kDa, Protein from rabbit)
60s ribosomal protein l27a (16 kDa, Protein from rabbit)
Ribosomal protein l15 (24 kDa, Protein from rabbit)
60s ribosomal protein l18a (20 kDa, Protein from rabbit)
60s ribosomal protein l12 (17 kDa, Protein from rabbit)
28s ribosomal rna (1 MDa, RNA from Oryctolagus cuniculus)
60s ribosomal protein l35a (12 kDa, Protein from rabbit)
60s ribosomal protein l17 (21 kDa, Protein from rabbit)
Zinc ion (65 Da, Ligand)
60s ribosomal protein l13 (24 kDa, Protein from rabbit)
60s ribosomal protein l36a-like (12 kDa, Protein from rabbit)
Ribosomal_l18_c domain-containing protein (34 kDa, Protein from rabbit)
60s ribosomal protein l27 (15 kDa, Protein from rabbit)
60s ribosomal protein l4 (47 kDa, Protein from rabbit)
60s ribosomal protein l28 (15 kDa, Protein from rabbit)
60s ribosomal protein l37a (10 kDa, Protein from rabbit)
Ribosomal protein l10 (24 kDa, Protein from rabbit)
60s ribosomal protein l23 (14 kDa, Protein from rabbit)
60s ribosomal protein l13a (23 kDa, Protein from rabbit)
60s ribosomal protein l9 (21 kDa, Protein from rabbit)
60s ribosomal protein l38 (8 kDa, Protein from rabbit)
60s ribosomal protein l36 (12 kDa, Protein from rabbit)
60s ribosomal protein l14 (23 kDa, Protein from rabbit)
60s acidic ribosomal protein p0 (34 kDa, Protein from rabbit)
60s ribosomal protein l8 (28 kDa, Protein from rabbit)
Ribosomal protein l37 (11 kDa, Protein from rabbit)
60s ribosomal protein l34 (13 kDa, Protein from rabbit)
60s ribosomal protein l41 (3 kDa, Protein from rabbit)
Rabbit 80s ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 (ttc5) and s-phase cyclin a associated protein residing in the er (scaper) (Complex from Oryctolagus cuniculus)
60s ribosomal protein l11 (20 kDa, Protein from rabbit)
S phase cyclin a-associated protein in the endoplasmic reticulum (159 kDa, Protein from Homo sapiens)
Tetratricopeptide repeat protein 5 (54 kDa, Protein from Homo sapiens)
Ribosomal protein l24 (17 kDa, Protein from rabbit)
Ribosomal protein l26 (17 kDa, Protein from rabbit)
60s ribosomal protein l39-like (6 kDa, Protein from rabbit)
60s ribosomal protein l21 (18 kDa, Protein from rabbit)
60s ribosomal protein l6 (33 kDa, Protein from rabbit)
60s ribosomal protein l7a (36 kDa, Protein from rabbit)
Nascent polypeptide-associated complex subunit alpha n-terminal region (2 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l29 (24 kDa, Protein from rabbit)
60s ribosomal protein l7 (29 kDa, Protein from rabbit)
60s ribosomal protein l31 (14 kDa, Protein from rabbit)
Ubiquitin-60s ribosomal protein l40 (11 kDa, Protein from rabbit)
Magnesium ion (24 Da, Ligand)
60s ribosomal protein l35 (14 kDa, Protein from rabbit)
Ribosomal protein l3 (46 kDa, Protein from rabbit)
Tubulin beta chain (7 kDa, Protein from Homo sapiens)
5s ribosomal rna (38 kDa, RNA from rabbit)
60s ribosomal protein l19 (23 kDa, Protein from rabbit)
60s ribosomal protein l30 (12 kDa, Protein from rabbit)
Ribosomal protein l32 (15 kDa, Protein from rabbit)
5.8s ribosomal rna (50 kDa, RNA from rabbit)
Ribosomal_l23en domain-containing protein (17 kDa, Protein from rabbit)

[Show more]

EMD-16232

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Structure of the TRAP complex with the Sec translocon and a translating ribosome

Release date: May 24, 2023
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8btk
Q-score: 0.362

Jaskolowski M, Jomaa A, Gamerdinger M, Shrestha S, Leibundgut M, Deuerling E, Ban N

Nat Struct Mol Biol (2023) 30 pp. 770-777 [ DOI: doi:10.1038/s41594-023-00990-0 Pubmed: 37170030 ]

Sample:

5.8s rrna (50 kDa, RNA from Oryctolagus cuniculus)
40s ribosomal protein s19 (16 kDa, Protein from Oryctolagus cuniculus)
28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
60s acidic ribosomal protein p0 (34 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s6 (28 kDa, Protein from Oryctolagus cuniculus)
Trap complex (Complex from canis lupus familiaris)
Ribosomal protein l3 (46 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l36 (12 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein s27a (18 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s7 (47 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s25 (13 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l10 (24 kDa, Protein from Oryctolagus cuniculus)
Es26 (13 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l28 (15 kDa, Protein from Oryctolagus cuniculus)
Guanosine-5'-triphosphate (523 Da, Ligand)
40s ribosomal protein s24 (15 kDa, Protein from Oryctolagus cuniculus)
Translocon-associated protein subunit beta (20 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s18 (17 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l22 (14 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l6 (33 kDa, Protein from Oryctolagus cuniculus)
Ribosomal small subunit (ssu) (Complex from Oryctolagus cuniculus)
Protein transport protein sec61 subunit beta (9 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l7a (30 kDa, Protein from Oryctolagus cuniculus)
Spermidine (145 Da, Ligand)
Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s8 (24 kDa, Protein from Oryctolagus cuniculus)
Ul22 (21 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l19 (23 kDa, Protein from Oryctolagus cuniculus)
El42 (12 kDa, Protein from Oryctolagus cuniculus)
Ribosomal_l23en domain-containing protein (17 kDa, Protein from Oryctolagus cuniculus)
Us14 (6 kDa, Protein from Oryctolagus cuniculus)
Ribosomal_s5_c domain-containing protein,40s ribosomal protein s2 (31 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s12 (14 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l29 (26 kDa, Protein from Oryctolagus cuniculus)
Protein transport protein sec61 subunit gamma (7 kDa, Protein from Canis lupus familiaris)
60s ribosomal protein l27a (16 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein us19 (17 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s14 (16 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s21 (9 kDa, Protein from Oryctolagus cuniculus)
Ubiquitin (14 kDa, Protein from Oryctolagus cuniculus)
P-site trna (24 kDa, RNA from Oryctolagus cuniculus)
Ribosomal protein l31 (14 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l34 (13 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein es10 (18 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l12 (17 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l23 (14 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l11 (20 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s11 (18 kDa, Protein from Oryctolagus cuniculus)
El32 (15 kDa, Protein from Oryctolagus cuniculus)
Translocon-associated protein subunit delta (18 kDa, Protein from Canis lupus familiaris)
Nascent chain (2 kDa, Protein from Saccharomyces cerevisiae)
60s ribosomal protein l18a (20 kDa, Protein from Oryctolagus cuniculus)
Spermine (202 Da, Ligand)
60s ribosomal protein l4 (46 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s4 (29 kDa, Protein from Oryctolagus cuniculus)
Protein transport protein sec61 subunit alpha isoform 1 (52 kDa, Protein from Canis lupus familiaris)
40s ribosomal protein us10 (13 kDa, Protein from Oryctolagus cuniculus)
Us9 (19 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s3a (30 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s27 (9 kDa, Protein from Oryctolagus cuniculus)
Structure of the trap complex with the sec translocon and a translating ribosome (Complex from Oryctolagus cuniculus)
El39 (6 kDa, Protein from Oryctolagus cuniculus)
Signal sequence receptor subunit 3 (21 kDa, Protein from Canis lupus familiaris)
40s ribosomal protein s30 (14 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein s15a (14 kDa, Protein from Oryctolagus cuniculus)
Rack1 (35 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s3 (31 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l21 (18 kDa, Protein from Oryctolagus cuniculus)
Translocon-associated protein subunit alpha (32 kDa, Protein from Canis lupus familiaris)
Acetylamino-acetic acid (117 Da, Ligand)
El38 (8 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein s9 (predicted) (22 kDa, Protein from Oryctolagus cuniculus)
Ul30,60s ribosomal protein l7 (29 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein es17 (15 kDa, Protein from Oryctolagus cuniculus)
Ribosomal large subunit (60s) (Complex from Oryctolagus cuniculus)
40s ribosomal protein s23 (15 kDa, Protein from Oryctolagus cuniculus)
El43 (10 kDa, Protein from Oryctolagus cuniculus)
Zinc ion (65 Da, Ligand)
60s ribosomal protein l13a (23 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l35 (14 kDa, Protein from Oryctolagus cuniculus)
P-site trna (Complex from Oryctolagus cuniculus)
Us15 (17 kDa, Protein from Oryctolagus cuniculus)
El18 (21 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l8 (28 kDa, Protein from Oryctolagus cuniculus)
Ribosomal_l18_c domain-containing protein (34 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l26 (17 kDa, Protein from Oryctolagus cuniculus)
Sec61 translocon (Complex from canis lupus familiaris)
Mrna (1 kDa, RNA from Oryctolagus cuniculus)
Ribosomal protein s5 (22 kDa, Protein from Oryctolagus cuniculus)
5s rrna (38 kDa, RNA from Oryctolagus cuniculus)
Ribosomal protein s28 (7 kDa, Protein from Oryctolagus cuniculus)
L13 (24 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein sa (32 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l24 (17 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein ul1 (24 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l35a (12 kDa, Protein from Oryctolagus cuniculus)
18s rrna (603 kDa, RNA from Oryctolagus cuniculus)
Magnesium ion (24 Da, Ligand)
Ribosomal protein l14 (23 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l9 (21 kDa, Protein from Oryctolagus cuniculus)
El30 (12 kDa, Protein from Oryctolagus cuniculus)

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EMD-15860

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Cryo-EM structure of ribosome-Sec61-TRAP (TRanslocon Associated Protein) translocon complex

Release date: March 1, 2023
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 8b5l
Q-score: 0.505

Pauwels E, Shewakramani NR, De Wijngaert B, Camps A, Provinciael B, Stroobants J, Kalies KU, Hartmann E, Maes P, Vermeire K, Das K

Sci Adv (2023) 9 pp. eadf0797-eadf0797 [ DOI: doi:10.1126/sciadv.adf0797 Pubmed: 36867692 ]

Sample:

Ribosomal protein l18 (21 kDa, Protein from rabbit)
60s ribosomal protein l11 (19 kDa, Protein from rabbit)
5.8s rrna (50 kDa, RNA from rabbit)
60s ribosomal protein l27a (16 kDa, Protein from rabbit)
60s ribosomal protein l18a (20 kDa, Protein from rabbit)
60s ribosomal protein l28 (14 kDa, Protein from rabbit)
Zinc ion (65 Da, Ligand)
60s ribosomal protein l29 (26 kDa, Protein from rabbit)
Ribosomal protein l37 (10 kDa, Protein from rabbit)
Ribosomal protein l26 (15 kDa, Protein from rabbit)
60s ribosomal protein l13 (24 kDa, Protein from rabbit)
60s ribosomal protein l21 (18 kDa, Protein from rabbit)
Ribosomal protein l19 (23 kDa, Protein from rabbit)
60s ribosomal protein l7 (26 kDa, Protein from rabbit)
60s ribosomal protein l35a (12 kDa, Protein from rabbit)
60s ribosomal protein l27 (15 kDa, Protein from rabbit)
Translocon-associated protein subunit alpha (32 kDa, Protein from Rabbit)
Ribosomal protein l10 (24 kDa, Protein from rabbit)
60s ribosomal protein l36a-like (12 kDa, Protein from rabbit)
60s ribosomal protein l13a (23 kDa, Protein from rabbit)
60s ribosomal protein l38 (8 kDa, Protein from rabbit)
Translocon-associated protein subunit delta (18 kDa, Protein from Rabbit)
60s ribosomal protein l36 (12 kDa, Protein from rabbit)
5s rrna (38 kDa, RNA from rabbit)
80s ribosome complex with sec61 and trap (Complex from Canis lupus familiaris)
60s ribosomal protein l41 (3 kDa, Protein from rabbit)
60s ribosomal protein l37a (10 kDa, Protein from rabbit)
60s ribosomal protein l34 (12 kDa, Protein from rabbit)
60s ribosomal protein l30 (10 kDa, Protein from rabbit)
Ribosomal protein l24 (17 kDa, Protein from rabbit)
Protein transport protein sec61 subunit alpha isoform 1 (52 kDa, Protein from Rabbit)
60s ribosomal protein l22 (11 kDa, Protein from rabbit)
Ribosomal protein l8 (28 kDa, Protein from rabbit)
Ribosomal_l18_c domain-containing protein (34 kDa, Protein from rabbit)
60s ribosomal protein l6 (33 kDa, Protein from rabbit)
Ribosomal protein l32 (15 kDa, Protein from rabbit)
60s ribosomal protein l23 (13 kDa, Protein from rabbit)
60s ribosomal protein l7a (36 kDa, Protein from rabbit)
60s ribosomal protein l17 (17 kDa, Protein from rabbit)
Signal sequence receptor subunit 3 (21 kDa, Protein from Rabbit)
60s ribosomal protein l14 (16 kDa, Protein from rabbit)
60s ribosomal protein l39-like (6 kDa, Protein from rabbit)
Ubiquitin-60s ribosomal protein l40 (6 kDa, Protein from rabbit)
60s ribosomal protein l35 (14 kDa, Protein from rabbit)
Ribosomal_l23en domain-containing protein (13 kDa, Protein from rabbit)
Ribosomal protein l15 (24 kDa, Protein from rabbit)
Magnesium ion (24 Da, Ligand)
60s ribosomal protein l9 (21 kDa, Protein from rabbit)
Translocon-associated protein subunit beta (20 kDa, Protein from Rabbit)
60s ribosomal protein l4 (41 kDa, Protein from rabbit)
28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
Ribosomal protein l3 (45 kDa, Protein from rabbit)
Protein transport protein sec61 subunit gamma (7 kDa, Protein from Rabbit)
60s ribosomal protein l31 (12 kDa, Protein from rabbit)

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EMD-15863

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Cryo-EM structure of ribosome-Sec61 in complex with cyclotriazadisulfonamide derivative CK147

Release date: Feb. 22, 2023
Resolution: 2.79 Å
EM Method: Single-particle
Fitted PDBs: 8b6c
Q-score: 0.516

Pauwels E, Shewakramani NR, De Wijngaert B, Camps A, Provinciael B, Stroobants J, Kalies KU, Hartmann E, Maes P, Vermeire K, Das K

Sci Adv (2023) 9 pp. eadf0797-eadf0797 [ DOI: doi:10.1126/sciadv.adf0797 Pubmed: 36867692 ]

Sample:

60s ribosomal protein l11 (19 kDa, Protein from rabbit)
5.8s rrna (50 kDa, RNA from rabbit)
60s ribosomal protein l22 (fragment) (11 kDa, Protein from rabbit)
60s ribosomal protein l27a (16 kDa, Protein from rabbit)
60s ribosomal protein l18a (20 kDa, Protein from rabbit)
60s ribosomal protein l28 (14 kDa, Protein from rabbit)
Zinc ion (65 Da, Ligand)
60s ribosomal protein l29 (26 kDa, Protein from rabbit)
Ribosomal protein l37 (10 kDa, Protein from rabbit)
Ribosomal protein l26 (15 kDa, Protein from rabbit)
80s ribosome complex with sec61 and inhibitor ck147 (Complex from Canis lupus familiaris)
60s ribosomal protein l13 (24 kDa, Protein from rabbit)
60s ribosomal protein l21 (18 kDa, Protein from rabbit)
60s ribosomal protein l7 (26 kDa, Protein from rabbit)
Protein transport protein sec61 subunit alpha isoform 1 (52 kDa, Protein from rabbit)
4-[[9-(cyclohexylmethyl)-3-methylidene-5-(4-methylphenyl)sulfonyl-1,5,9-triazacyclododec-1-yl]sulfonyl]-~{n},~{n}-dimethyl-aniline (616 Da, Ligand)
60s ribosomal protein l35a (12 kDa, Protein from rabbit)
60s ribosomal protein l27 (15 kDa, Protein from rabbit)
60s ribosomal protein l36a-like (12 kDa, Protein from rabbit)
Ribosomal protein l10 (24 kDa, Protein from rabbit)
60s ribosomal protein l13a (23 kDa, Protein from rabbit)
60s ribosomal protein l38 (8 kDa, Protein from rabbit)
El18 (21 kDa, Protein from rabbit)
60s ribosomal protein l36 (12 kDa, Protein from rabbit)
5s rrna (38 kDa, RNA from rabbit)
60s ribosomal protein l37a (10 kDa, Protein from rabbit)
60s ribosomal protein l30 (10 kDa, Protein from rabbit)
60s ribosomal protein l34 (12 kDa, Protein from rabbit)
60s ribosomal protein l41 (3 kDa, Protein from rabbit)
Ribosomal protein l24 (17 kDa, Protein from rabbit)
Ribosomal protein l8 (28 kDa, Protein from rabbit)
Ribosomal_l18_c domain-containing protein (34 kDa, Protein from rabbit)
60s ribosomal protein l23 (13 kDa, Protein from rabbit)
60s ribosomal protein l6 (33 kDa, Protein from rabbit)
Ribosomal protein l32 (15 kDa, Protein from rabbit)
60s ribosomal protein l7a (36 kDa, Protein from rabbit)
60s ribosomal protein l17 (17 kDa, Protein from rabbit)
60s ribosomal protein l14 (16 kDa, Protein from rabbit)
60s ribosomal protein l40 (6 kDa, Protein from rabbit)
60s ribosomal protein l39-like (6 kDa, Protein from rabbit)
Magnesium ion (24 Da, Ligand)
60s ribosomal protein l35 (14 kDa, Protein from rabbit)
Ribosomal_l23en domain-containing protein (13 kDa, Protein from rabbit)
Ribosomal protein l15 (24 kDa, Protein from rabbit)
60s ribosomal protein l9 (21 kDa, Protein from rabbit)
60s ribosomal protein l4 (41 kDa, Protein from rabbit)
28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
60s ribosomal protein l19 (23 kDa, Protein from rabbit)
Ribosomal protein l3 (45 kDa, Protein from rabbit)
Protein transport protein sec61 subunit gamma (7 kDa, Protein from Rabbit)
60s ribosomal protein l31 (12 kDa, Protein from rabbit)

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EMD-14751

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Rabbit 80S ribosome as it decodes the Sec-UGA codon

Release date: Oct. 19, 2022
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7zjw
Q-score: 0.514

Hilal T, Killam BY, Grozdanovic M, Dobosz-Bartoszek M, Loerke J, Burger J, Mielke T, Copeland PR, Simonovic M, Spahn CMT

Science (2022) 376 pp. 1338-1343 [ DOI: doi:10.1126/science.abg3875 Pubmed: 35709277 ]

Sample:

5.8s rrna (50 kDa, RNA from Oryctolagus cuniculus)
Crpv ires (Complex from Cricket paralysis virus)
60s ribosomal protein el22 (14 kDa, Protein from Oryctolagus cuniculus)
Human ser-trna-sec (28 kDa, RNA from Homo sapiens)
40s ribosomal protein s6 (28 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein ul30 (29 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l36 (12 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s7 (47 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s25 (13 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el28 (15 kDa, Protein from Oryctolagus cuniculus)
Guanosine-5'-triphosphate (523 Da, Ligand)
60s ribosomal protein l27a (16 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s24 (15 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
Gpx4 secis element (Complex from Rattus norvegicus)
60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
Crpv ires (345 kDa, RNA from Cricket paralysis virus)
40s ribosomal protein s18 (17 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l6 (33 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el24 (17 kDa, Protein from Oryctolagus cuniculus)
Serine (105 Da, Ligand)
80s ribosome (Complex from Oryctolagus cuniculus)
40s ribosomal protein s8 (24 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l19 (23 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein ul29 (14 kDa, Protein from Oryctolagus cuniculus)
Ser-trna-sec (Complex from Homo sapiens)
Ribosomal_l18_c domain-containing protein (34 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l3 (46 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el8 (30 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el38 (8 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l40 (14 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s12 (14 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l29 (26 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein p0 (34 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s28 (7 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l23 (14 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein us19 (17 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el21 (18 kDa, Protein from Oryctolagus cuniculus)
18s rrna (603 kDa, RNA from Oryctolagus cuniculus)
40s ribosomal protein es21 (9 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el13 (24 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s15a (14 kDa, Protein from Oryctolagus cuniculus)
Eefsec (67 kDa, Protein from Homo sapiens)
60s ribosomal protein l11 (20 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s27a (18 kDa, Protein from Oryctolagus cuniculus)
Secis binding protein 2 (95 kDa, Protein from Homo sapiens)
60s ribosomal protein l34 (13 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein us14 (6 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein es19 (16 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s11 (18 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein ul2 (28 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein ul22 (21 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el43 (10 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein us5 (31 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el31 (14 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l4 (46 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el30 (12 kDa, Protein from Oryctolagus cuniculus)
Eefsec and secis binding protein 2 (Complex from Homo sapiens)
40s ribosomal protein es4 (29 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein us10 (13 kDa, Protein from Oryctolagus cuniculus)
Water (18 Da, Ligand)
60s ribosomal protein ul13 (23 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s3a (30 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s27 (9 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l14 (23 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein es26 (13 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l10 (24 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s30 (14 kDa, Protein from Oryctolagus cuniculus)
Rack1 (35 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el20 (20 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s3 (31 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el42 (12 kDa, Protein from Oryctolagus cuniculus)
Sodium ion (22 Da, Ligand)
40s ribosomal protein es17 (15 kDa, Protein from Oryctolagus cuniculus)
80s-selenosome (3 MDa, Complex)
40s ribosomal protein s23 (15 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el39 (6 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein ul1 (24 kDa, Protein from Oryctolagus cuniculus)
Zinc ion (65 Da, Ligand)
40s ribosomal protein us11 (16 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el33 (12 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el32 (15 kDa, Protein from Oryctolagus cuniculus)
Gpx4 secis element (275 kDa, RNA from Rattus norvegicus)
60s ribosomal protein el18 (21 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein es10 (18 kDa, Protein from Oryctolagus cuniculus)
5s rrna (38 kDa, RNA from Oryctolagus cuniculus)
Potassium ion (39 Da, Ligand)
Ribosomal protein s5 (22 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein ul23 (17 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein sa (32 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s9 (22 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein us15 (17 kDa, Protein from Oryctolagus cuniculus)
28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
Magnesium ion (24 Da, Ligand)
60s ribosomal protein l9 (21 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l26 (17 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein us9 (19 kDa, Protein from Oryctolagus cuniculus)

[Show more]

EMD-14752

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Rabbit 80S ribosome programmed with SECIS and SBP2

Release date: Sept. 7, 2022
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7zjx
Q-score: 0.428

Hilal T, Killam BY, Grozdanovic M, Dobosz-Bartoszek M, Loerke J, Burger J, Mielke T, Copeland PR, Simonovic M, Spahn CMT

Science (2022) 376 pp. 1338-1343 [ DOI: doi:10.1126/science.abg3875 Pubmed: 35709277 ]

Sample:

5.8s rrna (50 kDa, RNA from Oryctolagus cuniculus)
Crpv ires (Complex from Cricket paralysis virus)
60s ribosomal protein el22 (14 kDa, Protein from Oryctolagus cuniculus)
Guanine nucleotide-binding protein subunit beta-2-like 1 (35 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s6 (28 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein ul30 (29 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l36 (12 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s7 (47 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s25 (13 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein (24 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el28 (15 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l10 (24 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l31 (14 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l27a (16 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s24 (15 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein es26 (13 kDa, Protein from Oryctolagus cuniculus)
Ubiquitin carboxyl extension protein 80 (18 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
Gpx4 secis element (Complex from Rattus norvegicus)
60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s18 (17 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l6 (33 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s20 (13 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s29 (6 kDa, Protein from Oryctolagus cuniculus)
80s ribosome (Complex from Oryctolagus cuniculus)
60s ribosomal protein ul3 (46 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s8 (24 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l19 (23 kDa, Protein from Oryctolagus cuniculus)
Ribosomal_l23en domain-containing protein (17 kDa, Protein from Oryctolagus cuniculus)
Ribosomal_l18_c domain-containing protein (34 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el8 (30 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l40 (14 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s12 (14 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l29 (26 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s28 (7 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l23 (14 kDa, Protein from Oryctolagus cuniculus)
18s rrna (603 kDa, RNA from Oryctolagus cuniculus)
40s ribosomal protein es21 (9 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el13 (24 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s15a (14 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l11 (20 kDa, Protein from Oryctolagus cuniculus)
S10_plectin domain-containing protein (18 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l34 (13 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s13 (17 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein es19 (16 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s11 (18 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein ul2 (28 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein ul22 (21 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el43 (10 kDa, Protein from Oryctolagus cuniculus)
Selenocysteine insertion sequence-binding protein 2 (95 kDa, Protein from Homo sapiens)
40s ribosomal protein us5 (31 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l4 (46 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s4 (29 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l30 (12 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s15 (17 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s17 (15 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein ul13 (23 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s3a (30 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s27 (9 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l14 (23 kDa, Protein from Oryctolagus cuniculus)
5s rrna (38 kDa, RNA from Oryctolagus cuniculus)
Selenocysteine insertion sequence-binding protein 2 (Complex from Homo sapiens)
40s ribosomal protein s30 (14 kDa, Protein from Oryctolagus cuniculus)
80s-sbp2-secis (3 MDa, Complex)
60s ribosomal protein el20 (20 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s3 (31 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l21 (18 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el42 (12 kDa, Protein from Oryctolagus cuniculus)
Crpv ires (52 kDa, RNA from Cricket paralysis virus)
Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l32 (15 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s23 (15 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein el39 (6 kDa, Protein from Oryctolagus cuniculus)
Zinc ion (65 Da, Ligand)
40s ribosomal protein us11 (16 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l35 (14 kDa, Protein from Oryctolagus cuniculus)
Gpx4 secis element (275 kDa, RNA from Rattus norvegicus)
60s ribosomal protein el18 (21 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l26 (17 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein s5 (22 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l38 (8 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein sa (32 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein l24 (17 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s9 (22 kDa, Protein from Oryctolagus cuniculus)
28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
60s ribosomal protein l35a (12 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l9 (21 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein us9 (19 kDa, Protein from Oryctolagus cuniculus)

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