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EMD-19576

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CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : PARENTAL STRAIN

Release date: May 15, 2024
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8rxh
Q-score: 0.603

Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H, Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E, Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF, Yonath A, Michaeli S

Cell Rep (2024) 43 pp. 114203-114203 [ Pubmed: 38722744 DOI: doi:10.1016/j.celrep.2024.114203 ]

Sample:

Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Leishmania major strain Friedlin)
Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s12 (15 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
(2s)-2-[2-[4-[[(2r,3s,4s)-3-acetyloxy-4-oxidanyl-pyrrolidin-2-yl]methyl]phenoxy]ethanoylamino]-6-azanyl-hexanoic acid (437 Da, Ligand)
Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
Lsub_rrna_chain_2 (492 kDa, RNA from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l13 (24 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
P-site_trna_chain_s3 (24 kDa, RNA from Leishmania major strain Friedlin)
Lsua_rrna_chain_1 (577 kDa, RNA from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Leishmania major strain Friedlin)
Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
Ribosomal protein s17 family protein (20 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
Water (18 Da, Ligand)
Ubiquitin-60s ribosomal protein l40 (17 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l10 (24 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
E-site_trna_chain_s4 (24 kDa, RNA from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
Sodium ion (22 Da, Ligand)
Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l7 (28 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
Mrna_chain_s5 (4 kDa, RNA from Leishmania major strain Friedlin)
60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
Zinc ion (65 Da, Ligand)
Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
Potassium ion (39 Da, Ligand)
A-site_trna_chain_s2 (24 kDa, RNA from Leishmania major strain Friedlin)
Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
Magnesium ion (24 Da, Ligand)
40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)
Cryo-em structure of leishmania major 80s ribosome with a/p/e-site trna and mrna (Complex from Leishmania major strain Friedlin)

[Show more]

EMD-19582

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CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : LM32Cs3H1 sKO STRAIN

Release date: May 15, 2024
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 8rxx
Q-score: 0.601

Cell Rep (2024) 43 pp. 114203-114203 [ Pubmed: 38722744 DOI: doi:10.1016/j.celrep.2024.114203 ]

Sample:

Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
Lsua_rrna_chain_1 (577 kDa, RNA from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s12 (15 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l13 (24 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
P-site_trna_chain_s3 (24 kDa, RNA from Leishmania major strain Friedlin)
5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
80s ribosome with a/p/e-site trna and mrna (Complex from Leishmania major strain Friedlin)
60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Leishmania major strain Friedlin)
Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
Ribosomal protein s17 family protein (20 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
Water (18 Da, Ligand)
Ubiquitin-60s ribosomal protein l40 (17 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l10 (24 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
E-site_trna_chain_s4 (24 kDa, RNA from Leishmania major strain Friedlin)
Lsub_rrna_chain_2 (492 kDa, RNA from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
Sodium ion (22 Da, Ligand)
Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l7 (28 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
Mrna_chain_s5 (4 kDa, RNA from Leishmania major strain Friedlin)
60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
Zinc ion (65 Da, Ligand)
Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
Potassium ion (39 Da, Ligand)
A-site_trna_chain_s2 (24 kDa, RNA from Leishmania major strain Friedlin)
Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
Magnesium ion (24 Da, Ligand)
40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)

[Show more]

EMD-17216

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CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : PARENTAL STRAIN

Release date: May 8, 2024
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8ovj
Q-score: 0.63

Cell Rep (2024) 43 pp. 114203-114203 [ Pubmed: 38722744 DOI: doi:10.1016/j.celrep.2024.114203 ]

Sample:

Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s12 (15 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
Lsua_rrna_chain_1 (577 kDa, RNA from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l13 (24 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
Lsub_rrna_chain_2 (492 kDa, RNA from Leishmania major strain Friedlin)
Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Leishmania major strain Friedlin)
E-site_trna_chain_s4 (6 kDa, RNA from Leishmania major strain Friedlin)
60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
Water (18 Da, Ligand)
Putative 60s ribosomal protein l10 (24 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s11 (20 kDa, Protein from Leishmania major strain Friedlin)
Sodium ion (22 Da, Ligand)
Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l7 (28 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
Zinc ion (65 Da, Ligand)
Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
80s ribosome from leishmania major (Complex from Leishmania major strain Friedlin)
Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
Potassium ion (39 Da, Ligand)
Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
Magnesium ion (24 Da, Ligand)
40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)

[Show more]

EMD-38752

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Cryo-EM structure of the human 40S ribosome with PDCD4

Release date: May 1, 2024
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8xxl
Q-score: 0.538

Ye X, Huang Z, Li Y, Wang M, Meng W, Miao M, Cheng J

Cell Res (2024) [ Pubmed: 38641729 DOI: doi:10.1038/s41422-024-00962-z ]

Sample:

40s ribosomal protein s19 (16 kDa, Protein from Homo sapiens)
40s ribosomal protein s12 (14 kDa, Protein from Homo sapiens)
40s ribosomal protein s5 (22 kDa, Protein from Homo sapiens)
40s ribosomal protein s13 (17 kDa, Protein from Homo sapiens)
18s rrna (602 kDa, RNA from Homo sapiens)
60s ribosomal protein l41 (3 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
40s ribosomal protein s26 (13 kDa, Protein from Homo sapiens)
40s ribosomal protein s15a (14 kDa, Protein from Homo sapiens)
40s ribosomal protein s3a (30 kDa, Protein from Homo sapiens)
40s ribosomal protein s3 (26 kDa, Protein from Homo sapiens)
40s ribosomal protein s20 (13 kDa, Protein from Homo sapiens)
40s ribosomal protein s15 (17 kDa, Protein from Homo sapiens)
Receptor of activated protein c kinase 1 (35 kDa, Protein from Homo sapiens)
40s ribosomal protein s2 (31 kDa, Protein from Homo sapiens)
40s ribosomal protein s27 (9 kDa, Protein from Homo sapiens)
40s ribosomal protein s8 (24 kDa, Protein from Homo sapiens)
40s ribosomal protein s29 (6 kDa, Protein from Homo sapiens)
40s ribosomal protein s25 (13 kDa, Protein from Homo sapiens)
40s ribosomal protein s24 (15 kDa, Protein from Homo sapiens)
40s ribosomal protein s11 (18 kDa, Protein from Homo sapiens)
40s ribosomal protein s10 (18 kDa, Protein from Homo sapiens)
40s ribosomal protein s6 (28 kDa, Protein from Homo sapiens)
40s ribosomal protein s30 (6 kDa, Protein from Homo sapiens)
40s ribosomal protein sa (32 kDa, Protein from Homo sapiens)
40s ribosomal protein s17 (15 kDa, Protein from Homo sapiens)
40s ribosomal protein s9 (22 kDa, Protein from Homo sapiens)
40s ribosome with pdcd4 (Complex from Homo sapiens)
40s ribosomal protein s16 (16 kDa, Protein from Homo sapiens)
40s ribosomal protein s23 (15 kDa, Protein from Homo sapiens)
40s ribosomal protein s28 (7 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
40s ribosomal protein s21 (9 kDa, Protein from Homo sapiens)
Programmed cell death protein 4 (51 kDa, Protein from Homo sapiens)
40s ribosomal protein s14 (16 kDa, Protein from Homo sapiens)
40s ribosomal protein s4, x isoform (29 kDa, Protein from Homo sapiens)
40s ribosomal protein s7 (22 kDa, Protein from Homo sapiens)
Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from Homo sapiens)
40s ribosomal protein s18 (17 kDa, Protein from Homo sapiens)

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EMD-38753

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Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G

Release date: May 1, 2024
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8xxm
Q-score: 0.491

Ye X, Huang Z, Li Y, Wang M, Meng W, Miao M, Cheng J

Cell Res (2024) [ Pubmed: 38641729 DOI: doi:10.1038/s41422-024-00962-z ]

Sample:

40s ribosomal protein s19 (16 kDa, Protein from Homo sapiens)
Eukaryotic translation initiation factor 3 subunit g (35 kDa, Protein from Homo sapiens)
40s ribosomal protein s12 (14 kDa, Protein from Homo sapiens)
40s ribosomal protein s5 (22 kDa, Protein from Homo sapiens)
40s ribosomal protein s13 (17 kDa, Protein from Homo sapiens)
18s rrna (602 kDa, RNA from Homo sapiens)
60s ribosomal protein l41 (3 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
40s ribosomal protein s26 (13 kDa, Protein from Homo sapiens)
40s ribosomal protein s15a (14 kDa, Protein from Homo sapiens)
40s ribosomal protein s3a (30 kDa, Protein from Homo sapiens)
40s ribosomal protein s3 (26 kDa, Protein from Homo sapiens)
40s ribosomal protein s20 (13 kDa, Protein from Homo sapiens)
40s ribosomal protein s15 (17 kDa, Protein from Homo sapiens)
Receptor of activated protein c kinase 1 (35 kDa, Protein from Homo sapiens)
40s ribosomal protein s2 (31 kDa, Protein from Homo sapiens)
40s ribosomal protein s27 (9 kDa, Protein from Homo sapiens)
40s ribosomal protein s8 (24 kDa, Protein from Homo sapiens)
40s ribosomal protein s29 (6 kDa, Protein from Homo sapiens)
40s ribosomal protein s25 (13 kDa, Protein from Homo sapiens)
40s ribosomal protein s24 (15 kDa, Protein from Homo sapiens)
40s ribosomal protein s11 (18 kDa, Protein from Homo sapiens)
40s ribosomal protein s10 (18 kDa, Protein from Homo sapiens)
40s ribosomal protein s6 (28 kDa, Protein from Homo sapiens)
40s ribosomal protein s30 (6 kDa, Protein from Homo sapiens)
40s ribosome with pdcd4 and eif4g (Complex from Homo sapiens)
40s ribosomal protein sa (32 kDa, Protein from Homo sapiens)
40s ribosomal protein s17 (15 kDa, Protein from Homo sapiens)
40s ribosomal protein s9 (22 kDa, Protein from Homo sapiens)
40s ribosomal protein s16 (16 kDa, Protein from Homo sapiens)
40s ribosomal protein s23 (15 kDa, Protein from Homo sapiens)
40s ribosomal protein s28 (7 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
40s ribosomal protein s21 (9 kDa, Protein from Homo sapiens)
Programmed cell death protein 4 (51 kDa, Protein from Homo sapiens)
40s ribosomal protein s14 (16 kDa, Protein from Homo sapiens)
40s ribosomal protein s4, x isoform (29 kDa, Protein from Homo sapiens)
40s ribosomal protein s7 (22 kDa, Protein from Homo sapiens)
Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from Homo sapiens)
40s ribosomal protein s18 (17 kDa, Protein from Homo sapiens)

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EMD-38754

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Cryo-EM structure of the human 43S ribosome with PDCD4

Release date: May 1, 2024
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8xxn
Q-score: 0.374

Ye X, Huang Z, Li Y, Wang M, Meng W, Miao M, Cheng J

Cell Res (2024) [ Pubmed: 38641729 DOI: doi:10.1038/s41422-024-00962-z ]

Sample:

40s ribosomal protein s19 (16 kDa, Protein from Homo sapiens)
Eukaryotic translation initiation factor 3 subunit g (35 kDa, Protein from Homo sapiens)
40s ribosomal protein s12 (14 kDa, Protein from Homo sapiens)
40s ribosomal protein s5 (22 kDa, Protein from Homo sapiens)
40s ribosomal protein s13 (17 kDa, Protein from Homo sapiens)
Eukaryotic translation initiation factor 3 subunit l (66 kDa, Protein from Homo sapiens)
18s rrna (602 kDa, RNA from Homo sapiens)
60s ribosomal protein l41 (3 kDa, Protein from Homo sapiens)
Eukaryotic translation initiation factor 3 subunit a (166 kDa, Protein from Homo sapiens)
Eukaryotic translation initiation factor 3 subunit f (37 kDa, Protein from Homo sapiens)
Eukaryotic initiation factor 4a-i (46 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
Eukaryotic translation initiation factor 3 subunit k (25 kDa, Protein from Homo sapiens)
40s ribosomal protein s26 (13 kDa, Protein from Homo sapiens)
40s ribosomal protein s15a (14 kDa, Protein from Homo sapiens)
Eukaryotic translation initiation factor 1 (12 kDa, Protein from Homo sapiens)
Eukaryotic translation initiation factor 3 subunit m (42 kDa, Protein from Homo sapiens)
40s ribosomal protein s3a (30 kDa, Protein from Homo sapiens)
40s ribosomal protein s3 (26 kDa, Protein from Homo sapiens)
40s ribosomal protein s20 (13 kDa, Protein from Homo sapiens)
Eukaryotic translation initiation factor 3 subunit c (105 kDa, Protein from Homo sapiens)
40s ribosomal protein s15 (17 kDa, Protein from Homo sapiens)
Receptor of activated protein c kinase 1 (35 kDa, Protein from Homo sapiens)
40s ribosomal protein s2 (31 kDa, Protein from Homo sapiens)
40s ribosomal protein s27 (9 kDa, Protein from Homo sapiens)
40s ribosomal protein s8 (24 kDa, Protein from Homo sapiens)
40s ribosomal protein s29 (6 kDa, Protein from Homo sapiens)
40s ribosomal protein s25 (13 kDa, Protein from Homo sapiens)
Eukaryotic translation initiation factor 3 subunit b (92 kDa, Protein from Homo sapiens)
40s ribosomal protein s24 (15 kDa, Protein from Homo sapiens)
40s ribosomal protein s11 (18 kDa, Protein from Homo sapiens)
Eukaryotic translation initiation factor 3 subunit i (36 kDa, Protein from Homo sapiens)
40s ribosomal protein s10 (18 kDa, Protein from Homo sapiens)
40s ribosomal protein s6 (28 kDa, Protein from Homo sapiens)
40s ribosomal protein s30 (6 kDa, Protein from Homo sapiens)
Eukaryotic translation initiation factor 3 subunit d (64 kDa, Protein from Homo sapiens)
Eukaryotic translation initiation factor 3 subunit e (52 kDa, Protein from Homo sapiens)
40s ribosomal protein sa (32 kDa, Protein from Homo sapiens)
40s ribosomal protein s17 (15 kDa, Protein from Homo sapiens)
Eukaryotic translation initiation factor 3 subunit h (39 kDa, Protein from Homo sapiens)
40s ribosomal protein s9 (22 kDa, Protein from Homo sapiens)
43s ribosome with pdcd4 (Complex from Homo sapiens)
40s ribosomal protein s16 (16 kDa, Protein from Homo sapiens)
40s ribosomal protein s23 (15 kDa, Protein from Homo sapiens)
40s ribosomal protein s28 (7 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
40s ribosomal protein s21 (9 kDa, Protein from Homo sapiens)
Programmed cell death protein 4 (51 kDa, Protein from Homo sapiens)
40s ribosomal protein s14 (16 kDa, Protein from Homo sapiens)
40s ribosomal protein s4, x isoform (29 kDa, Protein from Homo sapiens)
40s ribosomal protein s7 (22 kDa, Protein from Homo sapiens)
Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from Homo sapiens)
40s ribosomal protein s18 (17 kDa, Protein from Homo sapiens)

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EMD-36332

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Atomic structure of wheat ribosome reveals unique features of the plant ribosomes

Release date: March 27, 2024
Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 8jiw
Q-score: 0.481

Mishra RK, Sharma P, Khaja FT, Uday AB, Hussain T

Structure (2024) 32 pp. 562- [ Pubmed: 38458197 DOI: doi:10.1016/j.str.2024.02.006 ]

Sample:

40s ribosomal protein s15 (17 kDa, Protein from Triticum aestivum)
18s rrna (584 kDa, RNA from Triticum aestivum)
40s ribosomal protein s11 n-terminal domain-containing protein (18 kDa, Protein from Triticum aestivum)
40s ribosomal protein s19 (17 kDa, Protein from Triticum aestivum)
Ribosomal protein s10 domain-containing protein (13 kDa, Protein from Triticum aestivum)
Ribosomal protein s7 domain-containing protein (22 kDa, Protein from Triticum aestivum)
40s ribosomal protein s7 (22 kDa, Protein from Triticum aestivum)
Zinc ion (65 Da, Ligand)
40s ribosomal protein s16 (16 kDa, Protein from Triticum aestivum)
40s ribosomal protein s14 (16 kDa, Protein from Triticum aestivum)
Ribosomal protein s13/s15 n-terminal domain-containing protein (17 kDa, Protein from Triticum aestivum)
40s ribosomal protein s23 (15 kDa, Protein from Triticum aestivum)
40s ribosomal protein s25 (10 kDa, Protein from Triticum aestivum)
40s ribosomal protein s8 (25 kDa, Protein from Triticum aestivum)
40s ribosomal protein s18 (17 kDa, Protein from Triticum aestivum)
40s ribosomal protein s29 (6 kDa, Protein from Triticum aestivum)
40s ribosomal protein s6 (28 kDa, Protein from Triticum aestivum)
40s ribosomal protein s26 (15 kDa, Protein from Triticum aestivum)
40s ribosomal protein s3a (30 kDa, Protein from Triticum aestivum)
Potassium ion (39 Da, Ligand)
40s ribosomal protein s4 (30 kDa, Protein from Triticum aestivum)
30s ribosomal protein s4, chloroplastic (22 kDa, Protein from Triticum aestivum)
Kh type-2 domain-containing protein (25 kDa, Protein from Triticum aestivum)
40s ribosomal protein s21 (9 kDa, Protein from Triticum aestivum)
Plectin/s10 n-terminal domain-containing protein (20 kDa, Protein from Triticum aestivum)
40s ribosomal protein s24 (15 kDa, Protein from Triticum aestivum)
40s ribosomal protein s28 (7 kDa, Protein from Triticum aestivum)
40s ribosomal protein s30 (6 kDa, Protein from Triticum aestivum)
60s ribosomal protein l41 (3 kDa, Protein from Triticum aestivum)
The large subunit of wheat ribosome (Complex from Triticum aestivum)
40s ribosomal protein s17 (16 kDa, Protein from Triticum aestivum)
S5 drbm domain-containing protein (30 kDa, Protein from Triticum aestivum)
40s ribosomal protein sa (32 kDa, Protein from Triticum aestivum)
Mitogen-activated protein kinase (36 kDa, Protein from Triticum aestivum)
Magnesium ion (24 Da, Ligand)
30s ribosomal protein s8, chloroplastic (14 kDa, Protein from Triticum aestivum)
40s ribosomal protein s27 (9 kDa, Protein from Triticum aestivum)

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EMD-17329

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48S late-stage initiation complex with m6A mRNA

Release date: March 20, 2024
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 8p03
Q-score: 0.509

Guca E, Alarcon R, Palo MZ, Santos L, Alonso-Gil S, Davyt M, de Lima LHF, Boissier F, Das S, Zagrovic B, Puglisi JD, Hashem Y, Ignatova Z

Mol Cell (2024) 84 pp. 584-595.e6 [ DOI: doi:10.1016/j.molcel.2023.12.028 Pubmed: 38244546 ]

Sample:

Ribosomal protein s5 (21 kDa, Protein from Oryctolagus cuniculus)
Eukaryotic translation initiation factor 4c (12 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein es17 (15 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein s3 (25 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein us9 (15 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein es1 (24 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein es10 (11 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s12 (14 kDa, Protein from Oryctolagus cuniculus)
48s late-stage initiation complex with m6a-modified mrna (Complex from Oryctolagus cuniculus)
40s ribosomal protein us11 (16 kDa, Protein from Oryctolagus cuniculus)
M6a-methylated mrna (2 kDa, RNA from Oryctolagus cuniculus)
40s ribosomal protein s26 (12 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s28 (7 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein es31 (8 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s25 (13 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein es19 (15 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein us19 (17 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s8 (23 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein sa (23 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein us10 (13 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s21 (9 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s24 (15 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s6 (27 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
Atp binding cassette subfamily e member 1 (66 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s27 (9 kDa, Protein from Oryctolagus cuniculus)
Eukaryotic translation initiation factor 2 subunit 1 (32 kDa, Protein from Oryctolagus cuniculus)
Initiator methionylated trna (24 kDa, RNA from Oryctolagus cuniculus)
40s ribosomal protein s2 (29 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein s15a (14 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s30 (14 kDa, Protein from Oryctolagus cuniculus)
18s ribosomal rna (601 kDa, RNA from Oryctolagus cuniculus)
40s ribosomal protein s29 (6 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein es7 (21 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s9 (22 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein us13 (17 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s4 (29 kDa, Protein from Oryctolagus cuniculus)
Magnesium ion (24 Da, Ligand)
Ribosomal protein us15 (17 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein rack1 (34 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s23 (15 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s11 (18 kDa, Protein from Oryctolagus cuniculus)

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EMD-17330

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48S late-stage initiation complex with non methylated mRNA

Release date: March 20, 2024
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8p09
Q-score: 0.494

Guca E, Alarcon R, Palo MZ, Santos L, Alonso-Gil S, Davyt M, de Lima LHF, Boissier F, Das S, Zagrovic B, Puglisi JD, Hashem Y, Ignatova Z

Mol Cell (2024) 84 pp. 584-595.e6 [ DOI: doi:10.1016/j.molcel.2023.12.028 Pubmed: 38244546 ]

Sample:

Ribosomal protein s5 (21 kDa, Protein from Oryctolagus cuniculus)
Eukaryotic translation initiation factor 4c (12 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein es17 (15 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein s3 (25 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein us9 (15 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein es1 (24 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein es10 (11 kDa, Protein from Oryctolagus cuniculus)
Mrna (2 kDa, RNA from Oryctolagus cuniculus)
40s ribosomal protein s12 (14 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein us11 (16 kDa, Protein from Oryctolagus cuniculus)
48s late-stage initiation complex with non methylated mrna (Complex from Oryctolagus cuniculus)
40s ribosomal protein s26 (12 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s28 (7 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein es31 (8 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s25 (13 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein es19 (15 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein us19 (17 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s8 (23 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein sa (23 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein us10 (13 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s21 (9 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s24 (15 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s6 (27 kDa, Protein from Oryctolagus cuniculus)
60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
Atp binding cassette subfamily e member 1 (66 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s27 (9 kDa, Protein from Oryctolagus cuniculus)
Eukaryotic translation initiation factor 2 subunit 1 (32 kDa, Protein from Oryctolagus cuniculus)
Initiator methionylated trna (24 kDa, RNA from Oryctolagus cuniculus)
40s ribosomal protein s2 (29 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein s15a (14 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s30 (14 kDa, Protein from Oryctolagus cuniculus)
18s ribosomal rna (601 kDa, RNA from Oryctolagus cuniculus)
40s ribosomal protein s29 (6 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein es7 (21 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s9 (22 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein us13 (17 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s4 (29 kDa, Protein from Oryctolagus cuniculus)
Magnesium ion (24 Da, Ligand)
Ribosomal protein us15 (17 kDa, Protein from Oryctolagus cuniculus)
Ribosomal protein rack1 (34 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s23 (15 kDa, Protein from Oryctolagus cuniculus)
40s ribosomal protein s11 (18 kDa, Protein from Oryctolagus cuniculus)

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EMD-35413

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Dibekacin-added human 80S ribosome

Release date: Feb. 14, 2024
Resolution: 2.59 Å
EM Method: Single-particle
Fitted PDBs: 8ifd
Q-score: 0.539

Tomono J, Asano K, Chiashi T, Suzuki M, Igarashi M, Takahashi Y, Tanaka Y, Yokoyama T

J.Biochem. (2024) [ DOI: doi:10.1093/jb/mvae002 Pubmed: 38227611 ]

Sample:

60s ribosomal protein l24 (17 kDa, Protein from Homo sapiens)
Dbk-added human 80s ribosome (4 MDa, Complex from Homo sapiens)
60s ribosomal protein l41 (3 kDa, Protein from Homo sapiens)
40s ribosomal protein s26 (13 kDa, Protein from Homo sapiens)
60s ribosomal protein l10a (24 kDa, Protein from Homo sapiens)
40s ribosomal protein s20 (13 kDa, Protein from Homo sapiens)
60s ribosomal protein l4 (47 kDa, Protein from Homo sapiens)
60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
40s ribosomal protein s15 (17 kDa, Protein from Homo sapiens)
40s ribosomal protein s25 (13 kDa, Protein from Homo sapiens)
40s ribosomal protein s24 (15 kDa, Protein from Homo sapiens)
60s ribosomal protein l22 (14 kDa, Protein from Homo sapiens)
40s ribosomal protein s6 (28 kDa, Protein from Homo sapiens)
40s ribosomal protein s9 (22 kDa, Protein from Homo sapiens)
60s ribosomal protein l34 (13 kDa, Protein from Homo sapiens)
40s ribosomal protein s12 (14 kDa, Protein from Homo sapiens)
60s ribosomal protein l31 (14 kDa, Protein from Homo sapiens)
40s ribosomal protein s4, x isoform (29 kDa, Protein from Homo sapiens)
Large ribosomal subunit protein el40 (14 kDa, Protein from Homo sapiens)
60s ribosomal protein l17 (21 kDa, Protein from Homo sapiens)
40s ribosomal protein s19 (16 kDa, Protein from Homo sapiens)
60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
40s ribosomal protein s3a (30 kDa, Protein from Homo sapiens)
40s ribosomal protein s3 (26 kDa, Protein from Homo sapiens)
60s ribosomal protein l37 (11 kDa, Protein from Homo sapiens)
60s ribosomal protein l36 (12 kDa, Protein from Homo sapiens)
40s ribosomal protein s8 (24 kDa, Protein from Homo sapiens)
60s ribosomal protein l26 (17 kDa, Protein from Homo sapiens)
60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
40s ribosomal protein s11 (18 kDa, Protein from Homo sapiens)
Dibekacin (451 Da, Ligand)
60s ribosomal protein l30 (12 kDa, Protein from Homo sapiens)
60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
60s ribosomal protein l10-like (24 kDa, Protein from Homo sapiens)
60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
40s ribosomal protein s23 (15 kDa, Protein from Homo sapiens)
40s ribosomal protein s28 (7 kDa, Protein from Homo sapiens)
40s ribosomal protein s21 (9 kDa, Protein from Homo sapiens)
40s ribosomal protein s7 (22 kDa, Protein from Homo sapiens)
60s ribosomal protein l7 (29 kDa, Protein from Homo sapiens)
5.8s ribosomal rna (50 kDa, RNA from Homo sapiens)
60s ribosomal protein l11 (20 kDa, Protein from Homo sapiens)
60s ribosomal protein l39 (6 kDa, Protein from Homo sapiens)
60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
40s ribosomal protein s2 (31 kDa, Protein from Homo sapiens)
Receptor of activated protein c kinase 1 (35 kDa, Protein from Homo sapiens)
40s ribosomal protein s30 (6 kDa, Protein from Homo sapiens)
60s ribosomal protein l36a (12 kDa, Protein from Homo sapiens)
60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
40s ribosomal protein s17 (15 kDa, Protein from Homo sapiens)
60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
40s ribosomal protein s16 (16 kDa, Protein from Homo sapiens)
40s ribosomal protein s14 (16 kDa, Protein from Homo sapiens)
60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
40s ribosomal protein s18 (17 kDa, Protein from Homo sapiens)
60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)
40s ribosomal protein s5 (22 kDa, Protein from Homo sapiens)
60s ribosomal protein l14 (23 kDa, Protein from Homo sapiens)
40s ribosomal protein s13 (17 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
60s ribosomal protein l29 (17 kDa, Protein from Homo sapiens)
40s ribosomal protein s15a (14 kDa, Protein from Homo sapiens)
60s ribosomal protein l28 (15 kDa, Protein from Homo sapiens)
60s ribosomal protein l6 (32 kDa, Protein from Homo sapiens)
60s ribosomal protein l19 (23 kDa, Protein from Homo sapiens)
60s ribosomal protein l23a (17 kDa, Protein from Homo sapiens)
40s ribosomal protein s27 (9 kDa, Protein from Homo sapiens)
5s ribosomal rna (38 kDa, RNA from Homo sapiens)
40s ribosomal protein s29 (6 kDa, Protein from Homo sapiens)
60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
40s ribosomal protein s10 (18 kDa, Protein from Homo sapiens)
60s ribosomal protein l8 (28 kDa, Protein from Homo sapiens)
28s ribosomal rna (1 MDa, RNA from Homo sapiens)
40s ribosomal protein sa (32 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
60s ribosomal protein l3 (46 kDa, Protein from Homo sapiens)
60s ribosomal protein l7a (30 kDa, Protein from Homo sapiens)
18s ribosomal rna (602 kDa, RNA from Homo sapiens)
Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from Homo sapiens)

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