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Cryo-EM structure of a human pre-40S ribosomal subunit - State UTP14
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7wts
Q-score: 0.429
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen O, Hurt E, Beckmann R
Nucleic Acids Res (2022) 50 pp. 11924-11937 [ Pubmed: 36321656 DOI: doi:10.1093/nar/gkac961 ]
- 40s ribosomal protein s8 (24 kDa, Protein from human)
- Rrp12-like protein (143 kDa, Protein from human)
- 40s ribosomal protein s9 (22 kDa, Protein from human)
- Pre-rrna-processing protein tsr1 homolog (91 kDa, Protein from human)
- Yeast pre-40s ribosomal subunit (Complex from Homo sapiens)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from human)
- 40s ribosomal protein s24 (15 kDa, Protein from human)
- 18s rrna (604 kDa, RNA from Homo sapiens)
- 40s ribosomal protein s23 (15 kDa, Protein from human)
- 40s ribosomal protein s11 (18 kDa, Protein from human)
- 40s ribosomal protein s6 (28 kDa, Protein from human)
- Probable dimethyladenosine transferase (35 kDa, Protein from human)
- Ribosome biogenesis protein slx9 homolog (25 kDa, Protein from human)
- 40s ribosomal protein s7 (22 kDa, Protein from human)
- Probable 18s rrna (guanine-n(7))-methyltransferase (31 kDa, Protein from human)
- Rna-binding protein pno1 (27 kDa, Protein from human)
- 40s ribosomal protein s3a (30 kDa, Protein from human)
- 40s ribosomal protein s15a (14 kDa, Protein from human)
- U3 small nucleolar rna-associated protein 14 homolog a (88 kDa, Protein from human)
- 40s ribosomal protein s14 (16 kDa, Protein from human)
- Multifunctional methyltransferase subunit trm112-like protein (14 kDa, Protein from human)
- 40s ribosomal protein s13 (17 kDa, Protein from human)
- 40s ribosomal protein s27 (9 kDa, Protein from human)
- 40s ribosomal protein s30 (6 kDa, Protein from human)
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (with CK1)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7wtt
Q-score: 0.426
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen O, Hurt E, Beckmann R
Nucleic Acids Res (2022) 50 pp. 11924-11937 [ Pubmed: 36321656 DOI: doi:10.1093/nar/gkac961 ]
- 40s ribosomal protein s18 (17 kDa, Protein from human)
- 40s ribosomal protein s16 (16 kDa, Protein from human)
- 40s ribosomal protein s8 (24 kDa, Protein from human)
- Rrp12-like protein (143 kDa, Protein from human)
- 40s ribosomal protein s9 (22 kDa, Protein from human)
- Pre-rrna-processing protein tsr1 homolog (91 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- Yeast pre-40s ribosomal subunit (Complex from Homo sapiens)
- 40s ribosomal protein s15 (17 kDa, Protein from human)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from human)
- 40s ribosomal protein s24 (15 kDa, Protein from human)
- 40s ribosomal protein s23 (15 kDa, Protein from human)
- 40s ribosomal protein s28 (7 kDa, Protein from human)
- Bystin (49 kDa, Protein from human)
- 40s ribosomal protein s11 (18 kDa, Protein from human)
- 40s ribosomal protein s6 (28 kDa, Protein from human)
- Ribosome biogenesis protein slx9 homolog (25 kDa, Protein from human)
- 40s ribosomal protein s7 (22 kDa, Protein from human)
- 40s ribosomal protein s25 (13 kDa, Protein from human)
- Probable 18s rrna (guanine-n(7))-methyltransferase (31 kDa, Protein from human)
- Rna-binding protein pno1 (27 kDa, Protein from human)
- 40s ribosomal protein s3a (30 kDa, Protein from human)
- 40s ribosomal protein s19 (16 kDa, Protein from human)
- 40s ribosomal protein s15a (14 kDa, Protein from human)
- 40s ribosomal protein s12 (14 kDa, Protein from human)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- 18s rrna (604 kDa, RNA from Homo sapiens)
- Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from human)
- 40s ribosomal protein s5 (22 kDa, Protein from human)
- 40s ribosomal protein s14 (16 kDa, Protein from human)
- Multifunctional methyltransferase subunit trm112-like protein (14 kDa, Protein from human)
- 40s ribosomal protein s17 (15 kDa, Protein from human)
- Casein kinase i isoform alpha (38 kDa, Protein from human)
- 40s ribosomal protein s13 (17 kDa, Protein from human)
- Protein ltv1 homolog (54 kDa, Protein from human)
- 40s ribosomal protein s27 (9 kDa, Protein from human)
- 40s ribosomal protein s30 (6 kDa, Protein from human)
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (without CK1)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7wtu
Q-score: 0.43
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen O, Hurt E, Beckmann R
Nucleic Acids Res (2022) 50 pp. 11924-11937 [ Pubmed: 36321656 DOI: doi:10.1093/nar/gkac961 ]
- 40s ribosomal protein s18 (17 kDa, Protein from human)
- 40s ribosomal protein s16 (16 kDa, Protein from human)
- 40s ribosomal protein s8 (24 kDa, Protein from human)
- Rrp12-like protein (143 kDa, Protein from human)
- 40s ribosomal protein s9 (22 kDa, Protein from human)
- Pre-rrna-processing protein tsr1 homolog (91 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- Yeast pre-40s ribosomal subunit (Complex from Homo sapiens)
- 40s ribosomal protein s15 (17 kDa, Protein from human)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from human)
- 40s ribosomal protein s24 (15 kDa, Protein from human)
- 40s ribosomal protein s23 (15 kDa, Protein from human)
- 40s ribosomal protein s28 (7 kDa, Protein from human)
- Bystin (49 kDa, Protein from human)
- 40s ribosomal protein s11 (18 kDa, Protein from human)
- 40s ribosomal protein s6 (28 kDa, Protein from human)
- Ribosome biogenesis protein slx9 homolog (25 kDa, Protein from human)
- 40s ribosomal protein s7 (22 kDa, Protein from human)
- 40s ribosomal protein s25 (13 kDa, Protein from human)
- Probable 18s rrna (guanine-n(7))-methyltransferase (31 kDa, Protein from human)
- Rna-binding protein pno1 (27 kDa, Protein from human)
- 40s ribosomal protein s3a (30 kDa, Protein from human)
- 40s ribosomal protein s19 (16 kDa, Protein from human)
- 40s ribosomal protein s15a (14 kDa, Protein from human)
- 40s ribosomal protein s12 (14 kDa, Protein from human)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- 18s rrna (604 kDa, RNA from Homo sapiens)
- Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from human)
- 40s ribosomal protein s5 (22 kDa, Protein from human)
- 40s ribosomal protein s14 (16 kDa, Protein from human)
- Multifunctional methyltransferase subunit trm112-like protein (14 kDa, Protein from human)
- 40s ribosomal protein s17 (15 kDa, Protein from human)
- 40s ribosomal protein s13 (17 kDa, Protein from human)
- Protein ltv1 homolog (54 kDa, Protein from human)
- 40s ribosomal protein s27 (9 kDa, Protein from human)
- 40s ribosomal protein s30 (6 kDa, Protein from human)
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A2
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7wtv
Q-score: 0.378
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen O, Hurt E, Beckmann R
Nucleic Acids Res (2022) 50 pp. 11924-11937 [ Pubmed: 36321656 DOI: doi:10.1093/nar/gkac961 ]
- 40s ribosomal protein s18 (17 kDa, Protein from human)
- 40s ribosomal protein s16 (16 kDa, Protein from human)
- 40s ribosomal protein s8 (24 kDa, Protein from human)
- Rrp12-like protein (143 kDa, Protein from human)
- 40s ribosomal protein s9 (22 kDa, Protein from human)
- Pre-rrna-processing protein tsr1 homolog (91 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- Yeast pre-40s ribosomal subunit (Complex from Homo sapiens)
- 40s ribosomal protein s15 (17 kDa, Protein from human)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from human)
- 40s ribosomal protein s24 (15 kDa, Protein from human)
- 40s ribosomal protein s2 (31 kDa, Protein from human)
- 40s ribosomal protein s23 (15 kDa, Protein from human)
- 40s ribosomal protein s28 (7 kDa, Protein from human)
- Bystin (49 kDa, Protein from human)
- 40s ribosomal protein s11 (18 kDa, Protein from human)
- 40s ribosomal protein s6 (28 kDa, Protein from human)
- 40s ribosomal protein s21 (9 kDa, Protein from human)
- Ribosome biogenesis protein slx9 homolog (25 kDa, Protein from human)
- 40s ribosomal protein s7 (22 kDa, Protein from human)
- 40s ribosomal protein s25 (13 kDa, Protein from human)
- Probable 18s rrna (guanine-n(7))-methyltransferase (31 kDa, Protein from human)
- Rna-binding protein pno1 (27 kDa, Protein from human)
- 40s ribosomal protein s3a (30 kDa, Protein from human)
- 40s ribosomal protein s19 (16 kDa, Protein from human)
- 40s ribosomal protein s15a (14 kDa, Protein from human)
- 40s ribosomal protein s12 (14 kDa, Protein from human)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- 18s rrna (604 kDa, RNA from Homo sapiens)
- Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from human)
- 40s ribosomal protein sa (32 kDa, Protein from human)
- 40s ribosomal protein s5 (22 kDa, Protein from human)
- 40s ribosomal protein s14 (16 kDa, Protein from human)
- Multifunctional methyltransferase subunit trm112-like protein (14 kDa, Protein from human)
- 40s ribosomal protein s17 (15 kDa, Protein from human)
- 40s ribosomal protein s13 (17 kDa, Protein from human)
- 40s ribosomal protein s27 (9 kDa, Protein from human)
- 40s ribosomal protein s30 (6 kDa, Protein from human)
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A3
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7wtw
Q-score: 0.401
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen O, Hurt E, Beckmann R
Nucleic Acids Res (2022) 50 pp. 11924-11937 [ Pubmed: 36321656 DOI: doi:10.1093/nar/gkac961 ]
- 40s ribosomal protein s18 (17 kDa, Protein from human)
- 40s ribosomal protein s16 (16 kDa, Protein from human)
- 40s ribosomal protein s8 (24 kDa, Protein from human)
- Rrp12-like protein (143 kDa, Protein from human)
- 40s ribosomal protein s9 (22 kDa, Protein from human)
- Pre-rrna-processing protein tsr1 homolog (91 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- Yeast pre-40s ribosomal subunit (Complex from Homo sapiens)
- 40s ribosomal protein s15 (17 kDa, Protein from human)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from human)
- 40s ribosomal protein s24 (15 kDa, Protein from human)
- 40s ribosomal protein s2 (31 kDa, Protein from human)
- 40s ribosomal protein s23 (15 kDa, Protein from human)
- 40s ribosomal protein s28 (7 kDa, Protein from human)
- Bystin (49 kDa, Protein from human)
- 40s ribosomal protein s11 (18 kDa, Protein from human)
- 40s ribosomal protein s6 (28 kDa, Protein from human)
- 40s ribosomal protein s21 (9 kDa, Protein from human)
- Ribosome biogenesis protein slx9 homolog (25 kDa, Protein from human)
- 40s ribosomal protein s7 (22 kDa, Protein from human)
- 40s ribosomal protein s25 (13 kDa, Protein from human)
- Rna-binding protein pno1 (27 kDa, Protein from human)
- 40s ribosomal protein s3a (30 kDa, Protein from human)
- 40s ribosomal protein s19 (16 kDa, Protein from human)
- 40s ribosomal protein s15a (14 kDa, Protein from human)
- 40s ribosomal protein s12 (14 kDa, Protein from human)
- 18s rrna (604 kDa, RNA from Homo sapiens)
- Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from human)
- 40s ribosomal protein sa (32 kDa, Protein from human)
- 40s ribosomal protein s5 (22 kDa, Protein from human)
- Rna-binding protein nob1 (46 kDa, Protein from human)
- 40s ribosomal protein s14 (16 kDa, Protein from human)
- Multifunctional methyltransferase subunit trm112-like protein (14 kDa, Protein from human)
- 40s ribosomal protein s17 (15 kDa, Protein from human)
- 40s ribosomal protein s13 (17 kDa, Protein from human)
- Probable 18s rrna (guanine-n(7))-methyltransferase (22 kDa, Protein from human)
- Protein ltv1 homolog (54 kDa, Protein from human)
- 40s ribosomal protein s27 (9 kDa, Protein from human)
- 40s ribosomal protein s30 (6 kDa, Protein from human)
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-B1
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7wtx
Q-score: 0.478
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen O, Hurt E, Beckmann R
Nucleic Acids Res (2022) 50 pp. 11924-11937 [ Pubmed: 36321656 DOI: doi:10.1093/nar/gkac961 ]
- 40s ribosomal protein s16 (16 kDa, Protein from human)
- 40s ribosomal protein s18 (17 kDa, Protein from human)
- 40s ribosomal protein s8 (24 kDa, Protein from human)
- Rrp12-like protein (143 kDa, Protein from human)
- 40s ribosomal protein s9 (22 kDa, Protein from human)
- Pre-rrna-processing protein tsr1 homolog (91 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- Yeast pre-40s ribosomal subunit (Complex from Homo sapiens)
- 40s ribosomal protein s15 (17 kDa, Protein from human)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from human)
- 40s ribosomal protein s24 (15 kDa, Protein from human)
- 40s ribosomal protein s2 (31 kDa, Protein from human)
- 18s rrna (604 kDa, RNA from Homo sapiens)
- 40s ribosomal protein s23 (15 kDa, Protein from human)
- 40s ribosomal protein s28 (7 kDa, Protein from human)
- Bystin (49 kDa, Protein from human)
- 40s ribosomal protein s11 (18 kDa, Protein from human)
- 40s ribosomal protein s6 (28 kDa, Protein from human)
- 40s ribosomal protein s21 (9 kDa, Protein from human)
- 40s ribosomal protein s7 (22 kDa, Protein from human)
- 40s ribosomal protein s25 (13 kDa, Protein from human)
- Rna-binding protein pno1 (27 kDa, Protein from human)
- 40s ribosomal protein s3a (30 kDa, Protein from human)
- 40s ribosomal protein s19 (16 kDa, Protein from human)
- 40s ribosomal protein s15a (14 kDa, Protein from human)
- 40s ribosomal protein s12 (14 kDa, Protein from human)
- Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from human)
- 40s ribosomal protein sa (32 kDa, Protein from human)
- 40s ribosomal protein s5 (22 kDa, Protein from human)
- Rna-binding protein nob1 (46 kDa, Protein from human)
- 40s ribosomal protein s14 (16 kDa, Protein from human)
- 40s ribosomal protein s17 (15 kDa, Protein from human)
- 40s ribosomal protein s13 (17 kDa, Protein from human)
- Protein ltv1 homolog (54 kDa, Protein from human)
- 40s ribosomal protein s27 (9 kDa, Protein from human)
- 40s ribosomal protein s30 (6 kDa, Protein from human)
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-B2
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7wtz
Q-score: 0.482
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen O, Hurt E, Beckmann R
Nucleic Acids Res (2022) 50 pp. 11924-11937 [ Pubmed: 36321656 DOI: doi:10.1093/nar/gkac961 ]
- 40s ribosomal protein s16 (16 kDa, Protein from human)
- 40s ribosomal protein s18 (17 kDa, Protein from human)
- 40s ribosomal protein s8 (24 kDa, Protein from human)
- Rrp12-like protein (143 kDa, Protein from human)
- 40s ribosomal protein s9 (22 kDa, Protein from human)
- Pre-rrna-processing protein tsr1 homolog (91 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- Yeast pre-40s ribosomal subunit (Complex from Homo sapiens)
- 40s ribosomal protein s15 (17 kDa, Protein from human)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from human)
- 40s ribosomal protein s24 (15 kDa, Protein from human)
- 40s ribosomal protein s2 (31 kDa, Protein from human)
- 18s rrna (604 kDa, RNA from Homo sapiens)
- 40s ribosomal protein s23 (15 kDa, Protein from human)
- 40s ribosomal protein s28 (7 kDa, Protein from human)
- Bystin (49 kDa, Protein from human)
- 40s ribosomal protein s11 (18 kDa, Protein from human)
- 40s ribosomal protein s6 (28 kDa, Protein from human)
- 40s ribosomal protein s21 (9 kDa, Protein from human)
- 40s ribosomal protein s7 (22 kDa, Protein from human)
- 40s ribosomal protein s25 (13 kDa, Protein from human)
- Rna-binding protein pno1 (27 kDa, Protein from human)
- 40s ribosomal protein s3a (30 kDa, Protein from human)
- 40s ribosomal protein s19 (16 kDa, Protein from human)
- 40s ribosomal protein s15a (14 kDa, Protein from human)
- 40s ribosomal protein s12 (14 kDa, Protein from human)
- Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from human)
- 40s ribosomal protein sa (32 kDa, Protein from human)
- 40s ribosomal protein s5 (22 kDa, Protein from human)
- Rna-binding protein nob1 (46 kDa, Protein from human)
- 40s ribosomal protein s14 (16 kDa, Protein from human)
- 40s ribosomal protein s17 (15 kDa, Protein from human)
- 40s ribosomal protein s13 (17 kDa, Protein from human)
- Protein ltv1 homolog (54 kDa, Protein from human)
- 40s ribosomal protein s27 (9 kDa, Protein from human)
- 40s ribosomal protein s30 (6 kDa, Protein from human)
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-B3
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7wu0
Q-score: 0.414
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen O, Hurt E, Beckmann R
Nucleic Acids Res (2022) 50 pp. 11924-11937 [ Pubmed: 36321656 DOI: doi:10.1093/nar/gkac961 ]
- 40s ribosomal protein s16 (16 kDa, Protein from human)
- 40s ribosomal protein s18 (17 kDa, Protein from human)
- 40s ribosomal protein s8 (24 kDa, Protein from human)
- Rrp12-like protein (143 kDa, Protein from human)
- 40s ribosomal protein s9 (22 kDa, Protein from human)
- Pre-rrna-processing protein tsr1 homolog (91 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- Yeast pre-40s ribosomal subunit (Complex from Homo sapiens)
- 40s ribosomal protein s15 (17 kDa, Protein from human)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from human)
- 40s ribosomal protein s24 (15 kDa, Protein from human)
- 40s ribosomal protein s2 (31 kDa, Protein from human)
- 18s rrna (604 kDa, RNA from Homo sapiens)
- 40s ribosomal protein s23 (15 kDa, Protein from human)
- 40s ribosomal protein s28 (7 kDa, Protein from human)
- Bystin (49 kDa, Protein from human)
- Serine/threonine-protein kinase rio2 (63 kDa, Protein from human)
- 40s ribosomal protein s11 (18 kDa, Protein from human)
- 40s ribosomal protein s6 (28 kDa, Protein from human)
- 40s ribosomal protein s21 (9 kDa, Protein from human)
- 40s ribosomal protein s7 (22 kDa, Protein from human)
- 40s ribosomal protein s25 (13 kDa, Protein from human)
- Rna-binding protein pno1 (27 kDa, Protein from human)
- 40s ribosomal protein s3a (30 kDa, Protein from human)
- 40s ribosomal protein s19 (16 kDa, Protein from human)
- 40s ribosomal protein s15a (14 kDa, Protein from human)
- 40s ribosomal protein s12 (14 kDa, Protein from human)
- Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from human)
- 40s ribosomal protein sa (32 kDa, Protein from human)
- 40s ribosomal protein s5 (22 kDa, Protein from human)
- Rna-binding protein nob1 (46 kDa, Protein from human)
- 40s ribosomal protein s14 (16 kDa, Protein from human)
- 40s ribosomal protein s17 (15 kDa, Protein from human)
- 40s ribosomal protein s13 (17 kDa, Protein from human)
- Protein ltv1 homolog (54 kDa, Protein from human)
- 40s ribosomal protein s27 (9 kDa, Protein from human)
- 40s ribosomal protein s30 (6 kDa, Protein from human)
Cryo-EM structure of the human SSU processome, state pre-A1
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7mq8
Q-score: 0.417
Singh S, Vanden Broeck A, Miller L, Chaker-Margot M, Klinge S
Science (2021) 373 pp. eabj5338-eabj5338 [ DOI: doi:10.1126/science.abj5338 Pubmed: 34516797 ]
- Wd repeat-containing protein 75 (94 kDa, Protein from Homo sapiens)
- Rrna 2'-o-methyltransferase fibrillarin (33 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s12 (14 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- U3 small nucleolar rna-associated protein 15 homolog (58 kDa, Protein from Homo sapiens)
- Wd repeat-containing protein 3 (106 kDa, Protein from Homo sapiens)
- Wd repeat-containing protein 43 (74 kDa, Protein from Homo sapiens)
- Periodic tryptophan protein 2 homolog (102 kDa, Protein from Homo sapiens)
- Transducin beta-like protein 3 (89 kDa, Protein from Homo sapiens)
- Nucleolar protein 7 (29 kDa, Protein from Homo sapiens)
- Wd repeat-containing protein 36 (105 kDa, Protein from Homo sapiens)
- Deoxynucleotidyltransferase terminal-interacting protein 2 (84 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s28 (7 kDa, Protein from Homo sapiens)
- 5'ets rrna (4 kDa, RNA from Homo sapiens)
- U3 small nucleolar rna-associated protein 4 homolog (76 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s5 (22 kDa, Protein from Homo sapiens)
- Rna cytidine acetyltransferase (115 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s18 (12 kDa, Protein from Homo sapiens)
- Krr1 small subunit processome component homolog (43 kDa, Protein from Homo sapiens)
- Rna 3'-terminal phosphate cyclase-like protein (40 kDa, Protein from Homo sapiens)
- Nhp2-like protein 1 (14 kDa, Protein from Homo sapiens)
- Ribosome biogenesis protein bms1 homolog (145 kDa, Protein from Homo sapiens)
- Nucleolar protein 10 (80 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s17 (15 kDa, Protein from Homo sapiens)
- U3 small nucleolar rna-associated protein 14 homolog a (88 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s27 (9 kDa, Protein from Homo sapiens)
- Probable u3 small nucleolar rna-associated protein 11 (30 kDa, Protein from Homo sapiens)
- Ddb1- and cul4-associated factor 13 (51 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s8 (24 kDa, Protein from Homo sapiens)
- 18s rrna (602 kDa, RNA from Homo sapiens)
- Nucleolar protein 6 (127 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Rna-binding protein pno1 (27 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s11 (18 kDa, Protein from Homo sapiens)
- 5'ets rrna (1 MDa, RNA from Homo sapiens)
- Rrp12-like protein (73 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s23 (15 kDa, Protein from Homo sapiens)
- Human ssu processome (5 MDa, Complex from Homo sapiens)
- Small subunit processome component 20 homolog (318 kDa, Protein from Homo sapiens)
- Nucleolar complex protein 4 homolog (50 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s14 (16 kDa, Protein from Homo sapiens)
- U3 small nucleolar rna-associated protein 18 homolog (62 kDa, Protein from Homo sapiens)
- Neuroguidin (35 kDa, Protein from Homo sapiens)
- Unassigned peptides (15 kDa, Protein from Homo sapiens)
- U3 small nucleolar ribonucleoprotein protein mpp10 (78 kDa, Protein from Homo sapiens)
- Something about silencing protein 10 (54 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s7 (22 kDa, Protein from Homo sapiens)
- Heat repeat-containing protein 1 (242 kDa, Protein from Homo sapiens)
- U3 small nucleolar ribonucleoprotein protein imp3 (21 kDa, Protein from Homo sapiens)
- Ribosomal rna-processing protein 7 homolog a (32 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s3a (30 kDa, Protein from Homo sapiens)
- Ribosomal rna small subunit methyltransferase nep1 (26 kDa, Protein from Homo sapiens)
- Nucleolar protein 14 (68 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 40s ribosomal protein s24 (15 kDa, Protein from Homo sapiens)
- Nucleolar protein 11 (73 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s16 (16 kDa, Protein from Homo sapiens)
- U3 snorna (70 kDa, RNA from Homo sapiens)
- 40s ribosomal protein s13 (17 kDa, Protein from Homo sapiens)
- Wd repeat-containing protein 46 (68 kDa, Protein from Homo sapiens)
- Nucleolar protein 56 (66 kDa, Protein from Homo sapiens)
- U3 small nucleolar rna-interacting protein 2 (51 kDa, Protein from Homo sapiens)
- Bystin (33 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from Homo sapiens)
- U3 small nucleolar rna-associated protein 6 homolog (70 kDa, Protein from Homo sapiens)
- Protein aatf (63 kDa, Protein from Homo sapiens)
- Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s6 (28 kDa, Protein from Homo sapiens)
- Nucleolar protein 58 (59 kDa, Protein from Homo sapiens)
- Rrna-processing protein fcf1 homolog (23 kDa, Protein from Homo sapiens)
- U3 small nucleolar ribonucleoprotein protein imp4 (33 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s15a (14 kDa, Protein from Homo sapiens)
- Uncharacterized protein c1orf131 (32 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s9 (22 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
Cryo-EM structure of the human SSU processome, state pre-A1*
Resolution: 3.87 Å
EM Method: Single-particle
Fitted PDBs: 7mq9
Q-score: 0.357
Singh S, Vanden Broeck A, Miller L, Chaker-Margot M, Klinge S
Science (2021) 373 pp. eabj5338-eabj5338 [ DOI: doi:10.1126/science.abj5338 Pubmed: 34516797 ]
- Wd repeat-containing protein 75 (94 kDa, Protein from Homo sapiens)
- Rrna 2'-o-methyltransferase fibrillarin (33 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s12 (14 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- U3 small nucleolar rna-associated protein 15 homolog (58 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s4 x isoform (29 kDa, Protein from Homo sapiens)
- Wd repeat-containing protein 43 (74 kDa, Protein from Homo sapiens)
- Periodic tryptophan protein 2 homolog (102 kDa, Protein from Homo sapiens)
- Wd repeat-containing protein 3 (106 kDa, Protein from Homo sapiens)
- Nucleolar protein 7 (29 kDa, Protein from Homo sapiens)
- Transducin beta-like protein 3 (89 kDa, Protein from Homo sapiens)
- Wd repeat-containing protein 36 (105 kDa, Protein from Homo sapiens)
- Deoxynucleotidyltransferase terminal-interacting protein 2 (84 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s28 (7 kDa, Protein from Homo sapiens)
- U3 small nucleolar rna-associated protein 4 homolog (76 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s5 (22 kDa, Protein from Homo sapiens)
- Rna cytidine acetyltransferase (115 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s18 (12 kDa, Protein from Homo sapiens)
- Rna 3'-terminal phosphate cyclase-like protein (40 kDa, Protein from Homo sapiens)
- 5' ets rrna (7 kDa, RNA from Homo sapiens)
- Nhp2-like protein 1 (14 kDa, Protein from Homo sapiens)
- Krr1 small subunit processome component homolog (43 kDa, Protein from Homo sapiens)
- 18s rrna (603 kDa, RNA from Homo sapiens)
- Nucleolar protein 10 (80 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s17 (15 kDa, Protein from Homo sapiens)
- U3 small nucleolar rna-associated protein 14 homolog a (88 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s27 (9 kDa, Protein from Homo sapiens)
- Probable u3 small nucleolar rna-associated protein 11 (30 kDa, Protein from Homo sapiens)
- Ddb1- and cul4-associated factor 13 (51 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s8 (24 kDa, Protein from Homo sapiens)
- Nucleolar protein 6 (127 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Rna-binding protein pno1 (27 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s11 (18 kDa, Protein from Homo sapiens)
- 5'ets rrna (1 MDa, RNA from Homo sapiens)
- Rrp12-like protein (73 kDa, Protein from Homo sapiens)
- Ribosome biogenesis protein bms1 homolog (146 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s23 (15 kDa, Protein from Homo sapiens)
- Human ssu processome (5 MDa, Complex from Homo sapiens)
- Small subunit processome component 20 homolog (318 kDa, Protein from Homo sapiens)
- Nucleolar complex protein 4 homolog (50 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s14 (16 kDa, Protein from Homo sapiens)
- U3 small nucleolar rna-associated protein 18 homolog (62 kDa, Protein from Homo sapiens)
- Unassigned peptides (15 kDa, Protein from Homo sapiens)
- U3 small nucleolar ribonucleoprotein protein mpp10 (78 kDa, Protein from Homo sapiens)
- Something about silencing protein 10 (54 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s7 (22 kDa, Protein from Homo sapiens)
- Heat repeat-containing protein 1 (242 kDa, Protein from Homo sapiens)
- U3 small nucleolar ribonucleoprotein protein imp3 (21 kDa, Protein from Homo sapiens)
- Ribosomal rna small subunit methyltransferase nep1 (26 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s3a (30 kDa, Protein from Homo sapiens)
- Ribosomal rna-processing protein 7 homolog a (32 kDa, Protein from Homo sapiens)
- Nucleolar protein 14 (68 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 40s ribosomal protein s24 (15 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- 40s ribosomal protein s16 (16 kDa, Protein from Homo sapiens)
- U3 snorna (70 kDa, RNA from Homo sapiens)
- Nucleolar protein 11 (75 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s13 (17 kDa, Protein from Homo sapiens)
- Wd repeat-containing protein 46 (68 kDa, Protein from Homo sapiens)
- Nucleolar protein 56 (66 kDa, Protein from Homo sapiens)
- U3 small nucleolar rna-interacting protein 2 (51 kDa, Protein from Homo sapiens)
- Bystin (33 kDa, Protein from Homo sapiens)
- Protein aatf (63 kDa, Protein from Homo sapiens)
- U3 small nucleolar rna-associated protein 6 homolog (70 kDa, Protein from Homo sapiens)
- Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s6 (28 kDa, Protein from Homo sapiens)
- Nucleolar protein 58 (59 kDa, Protein from Homo sapiens)
- Rrna-processing protein fcf1 homolog (23 kDa, Protein from Homo sapiens)
- U3 small nucleolar ribonucleoprotein protein imp4 (33 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s15a (14 kDa, Protein from Homo sapiens)
- Uncharacterized protein c1orf131 (32 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s9 (22 kDa, Protein from Homo sapiens)
- S-adenosyl-l-homocysteine (384 Da, Ligand)