Do data resources managed by EMBL-EBI and our collaborators make a difference to your work? Please take 10 minutes to fill in our annual user survey, and help us make the case for why sustaining open data resources is critical for life sciences research. We appreciate your responses prior to closing of the survey on Monday 17th June.
Resolution: 4.09 Å
EM Method: Single-particle
Fitted PDBs: 8a43
Q-score: 0.337
Daiss JL, Pilsl M, Straub K, Bleckmann A, Hocherl M, Heiss FB, Abascal-Palacios G, Ramsay EP, Tluckova K, Mars JC, Furtges T, Bruckmann A, Rudack T, Bernecky C, Lamour V, Panov K, Vannini A, Moss T, Engel C
Life Sci Alliance (2022) 5 [ DOI: doi:10.26508/lsa.202201568 Pubmed: 36271492 ]
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa12 (13 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
- Rna polymerase i (Complex from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa2 (128 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa34 (55 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa1 (195 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa49 (47 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
Structure of transcription factor UAF in complex with TBP and 35S rRNA promoter DNA
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7z0o
Q-score: 0.507
Baudin F, Murciano B, Fung HKH, Fromm SA, Mattei S, Mahamid J, Muller CW
Sci Adv (2022) 8 pp. eabn5725-eabn5725 [ DOI: doi:10.1126/sciadv.abn5725 Pubmed: 35442737 ]
- Histone h4 (11 kDa, Protein from Saccharomyces cerevisiae)
- Non-template dna (47 kDa, DNA from Saccharomyces cerevisiae)
- Rna polymerase i-specific transcription initiation factor rrn5 (41 kDa, Protein from Saccharomyces cerevisiae)
- Histone h3 (15 kDa, Protein from Saccharomyces cerevisiae)
- Upstream activating factor (uaf) bound to tbp and promoter dna (Complex from Saccharomyces cerevisiae)
- Rna polymerase i-specific transcription initiation factor rrn9 (42 kDa, Protein from Saccharomyces cerevisiae)
- Rna polymerase i-specific transcription initiation factor rrn10 (16 kDa, Protein from Saccharomyces cerevisiae)
- Tata-box-binding protein (27 kDa, Protein from Saccharomyces cerevisiae)
- Upstream activation factor subunit uaf30 (26 kDa, Protein from Saccharomyces cerevisiae)
- Template dna (45 kDa, DNA from Saccharomyces cerevisiae)
Structure of the post state human RNA Polymerase I Elongation Complex
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 7vbb
Q-score: 0.401
Zhao D, Liu W, Chen K, Wu Z, Yang H, Xu Y
Cell Discov (2021) 7 pp. 97-97 [ DOI: doi:10.1038/s41421-021-00335-5 Pubmed: 34671025 ]
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
- Rna (5'-r(p*up*gp*cp*up*gp*ap*cp*u)-3') (2 kDa, RNA from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
- Dna (5'-d(*cp*tp*gp*tp*cp*cp*tp*cp*tp*gp*gp*cp*gp*a)-3') (4 kDa, DNA from Homo sapiens)
- Dna (25-mer) (7 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa43 (37 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
- Post state of human rna polymerase i elongation complex (Complex from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa49 (47 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa1 (194 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa12 (13 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa2 (128 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa34 (55 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
Structure of the pre state human RNA Polymerase I Elongation Complex
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 7vba
Q-score: 0.525
Zhao D, Liu W, Chen K, Wu Z, Yang H, Xu Y
Cell Discov (2021) 7 pp. 97-97 [ DOI: doi:10.1038/s41421-021-00335-5 Pubmed: 34671025 ]
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
- Rna (5'-r(p*up*gp*cp*up*gp*ap*cp*u)-3') (2 kDa, RNA from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa43 (37 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa49 (47 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa1 (194 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa12 (13 kDa, Protein from Homo sapiens)
- Dna (5'-d(p*a*cp*tp*gp*tp*cp*cp*tp*cp*tp*gp*gp*c)-3') (3 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa2 (128 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa34 (55 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
- 5'-o-[(s)-hydroxy{[(s)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine (481 Da, Ligand)
- Dna (5'-d(p*gp*cp*cp*ap*gp*ap*gp*ap*cp*ap*gp*cp*gp*ap*gp*tp*cp*ap*gp*cp*ap*a)-3') (6 kDa, DNA from Homo sapiens)
- Human rna polymerase i elongation complex (Complex from Homo sapiens)
Back track state of human RNA Polymerase I Elongation Complex
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 7vbc
Q-score: 0.373
Zhao D, Liu W, Chen K, Wu Z, Yang H, Xu Y
Cell Discov (2021) 7 pp. 97-97 [ DOI: doi:10.1038/s41421-021-00335-5 Pubmed: 34671025 ]
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
- Back track state of human rna polymerase i elongation complex (Complex from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa43 (37 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa49 (47 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa1 (194 kDa, Protein from Homo sapiens)
- Rna (5'-r(p*up*gp*cp*up*gp*a)-3') (1 kDa, RNA from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa12 (13 kDa, Protein from Homo sapiens)
- Dna (5'-d(*gp*tp*ap*cp*tp*gp*tp*cp*cp*tp*cp*tp*gp*g)-3') (4 kDa, DNA from Homo sapiens)
- Dna (5'-d(p*ap*gp*gp*ap*cp*ap*gp*cp*gp*tp*gp*tp*cp*ap*gp*cp*ap*ap*tp*a)-3') (6 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa2 (128 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa34 (55 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
Cryo-EM structure of human RNA Polymerase I in elongation state
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7ob9
Q-score: 0.519
Misiaszek AD, Girbig M, Grotsch H, Baudin F, Murciano B, Lafita A, Muller CW
Nat Struct Mol Biol (2021) 28 pp. 997-1008 [ DOI: doi:10.1038/s41594-021-00693-4 Pubmed: 34887565 ]
- Rna and dna (Complex from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Human)
- Dna non-template strand (13 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa43 (37 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa12 (13 kDa, Protein from Human)
- Rna (9 kDa, RNA from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa1 (195 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa2 (128 kDa, Protein from Human)
- Dna template strand (13 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Human)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa34 (55 kDa, Protein from Human)
- Rna polymerase i (Complex from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa49 (47 kDa, Protein from Human)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Human)
- Rna polymerase i (Complex)
Cryo-EM structure of human RNA Polymerase I in complex with RRN3
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7oba
Q-score: 0.435
Misiaszek AD, Girbig M, Grotsch H, Baudin F, Murciano B, Lafita A, Muller CW
Nat Struct Mol Biol (2021) 28 pp. 997-1008 [ DOI: doi:10.1038/s41594-021-00693-4 Pubmed: 34887565 ]
- Rna polymerase i-specific transcription initiation factor rrn3 (74 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa34 (55 kDa, Protein from Human)
- Zinc ion (65 Da, Ligand)
- Rna polymerase i-specific transcription initiation factor rrn3 (Complex from Homo sapiens)
- Rna polymerase i (Complex from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa12 (13 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa1 (195 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa2 (128 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa49 (47 kDa, Protein from Human)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa43 (37 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Human)
- Rna polymerase i in complex with rrn3 (670 kDa, Complex)
Cryo-EM structure of human RNA Polymerase I Open Complex
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7obb
Q-score: 0.401
Misiaszek AD, Girbig M, Grotsch H, Baudin F, Murciano B, Lafita A, Muller CW
Nat Struct Mol Biol (2021) 28 pp. 997-1008 [ DOI: doi:10.1038/s41594-021-00693-4 Pubmed: 34887565 ]
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Human)
- Dna non-template strand (13 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa12 (13 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa43 (37 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa1 (195 kDa, Protein from Human)
- Dna (Complex from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa2 (128 kDa, Protein from Human)
- Dna template strand (13 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Human)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Human)
- Rna polymerase i open complex (600 kDa, Complex)
- Dna-directed rna polymerase i subunit rpa34 (55 kDa, Protein from Human)
- Rna polymerase i (Complex from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Human)
- Dna-directed rna polymerase i subunit rpa49 (47 kDa, Protein from Human)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Human)
Schizosaccharomyces pombe RNA polymerase I (monomer)
Resolution: 3.84 Å
EM Method: Single-particle
Fitted PDBs: 7aoc
Q-score: 0.449
Heiss FB, Daiss JL, Becker P, Engel C
Nat Commun (2021) 12 pp. 758-758 [ Pubmed: 33536435 DOI: doi:10.1038/s41467-021-21031-8 ]
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Fission yeast)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (15 kDa, Protein from Fission yeast)
- Probable dna-directed rna polymerase i subunit rpa2 (131 kDa, Protein from Fission yeast)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (23 kDa, Protein from Fission yeast)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Fission yeast)
- Dna-directed rna polymerase i subunit rpa12 (13 kDa, Protein from Fission yeast)
- Dna-directed rna polymerase i subunit rpa43 (19 kDa, Protein from Fission yeast)
- Dna-directed rna polymerase i subunit rpa14 (17 kDa, Protein from Fission yeast)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (8 kDa, Protein from Fission yeast)
- Dna-directed rna polymerases i and iii subunit rpac2 (13 kDa, Protein from Fission yeast)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (14 kDa, Protein from Fission yeast)
- Zinc ion (65 Da, Ligand)
- S. pombe rna polymerase i (Complex from Schizosaccharomyces pombe (strain 972 / ATCC 24843))
- Dna-directed rna polymerase i subunit rpa1 (189 kDa, Protein from Fission yeast)
Schizosaccharomyces pombe RNA polymerase I (dimer)
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7aod
Q-score: 0.309
Heiss FB, Daiss JL, Becker P, Engel C
Nat Commun (2021) 12 pp. 758-758 [ Pubmed: 33536435 DOI: doi:10.1038/s41467-021-21031-8 ]
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Fission yeast)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (15 kDa, Protein from Fission yeast)
- Probable dna-directed rna polymerase i subunit rpa2 (131 kDa, Protein from Fission yeast)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (23 kDa, Protein from Fission yeast)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Fission yeast)
- Dna-directed rna polymerase i subunit rpa12 (13 kDa, Protein from Fission yeast)
- Dna-directed rna polymerase i subunit rpa43 (19 kDa, Protein from Fission yeast)
- Dna-directed rna polymerase i subunit rpa14 (17 kDa, Protein from Fission yeast)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (8 kDa, Protein from Fission yeast)
- Dna-directed rna polymerases i and iii subunit rpac2 (13 kDa, Protein from Fission yeast)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (14 kDa, Protein from Fission yeast)
- Zinc ion (65 Da, Ligand)
- S. pombe rna polymerase i (Complex from Schizosaccharomyces pombe (strain 972 / ATCC 24843))
- Dna-directed rna polymerase i subunit rpa1 (189 kDa, Protein from Fission yeast)