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SARS-CoV-2 RNA E-RTC complex with RMP-nsp9 and GMPPNP
Resolution: 2.72 Å
EM Method: Single-particle
Fitted PDBs: 8gwk
Q-score: 0.423
Yan L, Huang Y, Ge J, Liu Z, Lu P, Huang B, Gao S, Wang J, Tan L, Ye S, Yu F, Lan W, Xu S, Zhou F, Shi L, Guddat LW, Gao Y, Rao Z, Lou Z
Cell (2022) 185 pp. 4347-4360.e17 [ Pubmed: 36335936 DOI: doi:10.1016/j.cell.2022.09.037 ]
- Non-structural protein 9 (12 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Primer (8 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- Helicase (66 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Water (18 Da, Ligand)
- Non-structural protein 7 (9 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- E-rtc_rmp-nsp9_gmppnp (Complex from Severe acute respiratory syndrome coronavirus 2)
- Magnesium ion (24 Da, Ligand)
- Template (8 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 8 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rna-directed rna polymerase (106 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- [(2~{r},3~{s},4~{r},5~{r})-5-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate (371 Da, Ligand)
- Zinc ion (65 Da, Ligand)
SARS-CoV-2 E-RTC bound with MMP-nsp9 and GMPPNP
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 8gwm
Q-score: 0.41
Yan L, Huang Y, Ge J, Liu Z, Lu P, Huang B, Gao S, Wang J, Tan L, Ye S, Yu F, Lan W, Xu S, Zhou F, Shi L, Guddat LW, Gao Y, Rao Z, Lou Z
Cell (2022) 185 pp. 4347-4360.e17 [ Pubmed: 36335936 DOI: doi:10.1016/j.cell.2022.09.037 ]
- Non-structural protein 9 (12 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- Rna (25-mer) (8 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Helicase (66 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2'-deoxy-2'-fluoro-2'-methyluridine 5'-(trihydrogen diphosphate) (420 Da, Ligand)
- E-rtc_mmp-nsp9_gmppnp (Complex from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 7 (9 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rna (26-mer) (8 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 8 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rna-directed rna polymerase (106 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Water (18 Da, Ligand)
- Zinc ion (65 Da, Ligand)
Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
Resolution: 3.93 Å
EM Method: Single-particle
Fitted PDBs: 8hl1
Q-score: 0.332
Wang YH, Dai H, Zhang L, Wu Y, Wang J, Wang C, Xu CH, Hou H, Yang B, Zhu Y, Zhang X, Zhou J
Nucleic Acids Res (2023) 51 pp. 8909-8924 [ DOI: doi:10.1093/nar/gkad661 Pubmed: 37604686 ]
- 50s ribosomal protein l40e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l18 (21 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l21e (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l24 (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l23 (9 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l47a (9 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 5s rrna (122-mer) (39 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l22 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l30e (10 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l5 (19 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Small ribosomal subunit protein us8 (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s19e (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s11 (13 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s17 (12 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s13 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s27ae (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l15 (16 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Elongation factor 2 (81 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s12 (15 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Trna (76-mer) (24 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s27e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- 50s ribosomal protein l31e (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l18ae (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Conserved protein (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l24e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 23s rrna (3000-mer) (980 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s3 (22 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l18e (12 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s10 (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s14 type z (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s2 (22 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s24e (10 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l4 (27 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 16s rrna (1493-mer) (484 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l2 (24 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l19e (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Mrna (5'-r(p*up*up*up*up*up*up*up*up*up*up*up*up*u)-3') (3 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l6 (20 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l7ae (13 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s28e (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s4e (27 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s6e (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Unknown (103 Da, Ligand)
- 50s ribosomal protein l13 (15 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s5 (22 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s7 (21 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l10e (18 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l37e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l37ae (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s3ae (21 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Sulfolobus acidocaldarius ribosome small sbunit (Complex from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s17e (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l14e (9 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l15e (20 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l29 (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l34e (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l14 (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s9 (15 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l44e (10 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s15 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l30 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l32e (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l39e (5 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l3 (38 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Phe-phe-phe-phe-phe-phe (901 Da, Protein from Sulfolobus acidocaldarius DSM 639)
- Duf2280 domain-containing protein (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s8e (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s19 (13 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l1 (24 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s4 (19 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
Cryo-EM structure of Rab29-LRRK2 complex in the LRRK2 monomer state
Resolution: 4.13 Å
EM Method: Single-particle
Fitted PDBs: 8fo2
Q-score: 0.333
Zhu H, Tonelli F, Turk M, Prescott A, Alessi DR, Sun J
Science (2023) 382 pp. 1404-1411 [ DOI: doi:10.1126/science.adi9926 Pubmed: 38127736 ]
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- Leucine-rich repeat serine/threonine-protein kinase 2 (286 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Lrrk2-rab29 (Complex from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Ras-related protein rab-7l1 (20 kDa, Protein from Homo sapiens)
human mitoribosomal large subunit assembly intermediate 1 with GTPBP10-GTPBP7
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8pk0
Q-score: 0.455
Nat Commun (2023) 14 pp. 7991-7991 [ DOI: doi:10.1038/s41467-023-43599-z Pubmed: 38042949 ]
- Acyl carrier protein, mitochondrial (17 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Homo sapiens)
- Mitochondrial ribosome-associated gtpase 1 (37 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Homo sapiens)
- Large mitoribosomal subunit biogenesis intermediate with gtpbp10, gtpbp7, nsun4-mterf4, acp-module (1 MDa, Complex from Homo sapiens)
- 16s rrna + pre-h68-71 segment (509 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Homo sapiens)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Homo sapiens)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- 39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Homo sapiens)
- Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Homo sapiens)
- S-adenosylmethionine (398 Da, Ligand)
- Mief1 upstream open reading frame protein (8 kDa, Protein from Homo sapiens)
- Mitochondrial assembly of ribosomal large subunit protein 1 (26 kDa, Protein from Homo sapiens)
- Ribosomal protein 63, mitochondrial (12 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Homo sapiens)
- S-(2-{[n-(2-hydroxy-4-{[hydroxy(oxido)phosphino]oxy}-3,3-dimethylbutanoyl)-beta-alanyl]amino}ethyl) decanethioate (496 Da, Ligand)
- 39s ribosomal protein l46, mitochondrial (31 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l54, mitochondrial (15 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l40, mitochondrial (24 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l43, mitochondrial (23 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l48, mitochondrial (23 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cp trna-val (22 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Homo sapiens)
- 5-methylcytosine rrna methyltransferase nsun4 (43 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Homo sapiens)
- Gtp-binding protein 10 (42 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Homo sapiens)
- Transcription termination factor 4, mitochondrial (44 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Homo sapiens)
- 39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l33, mitochondrial (7 kDa, Protein from Homo sapiens)
- 39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Homo sapiens)
Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
Resolution: 4.62 Å
EM Method: Single-particle
Fitted PDBs: 8hl4
Q-score: 0.279
Wang YH, Dai H, Zhang L, Wu Y, Wang J, Wang C, Xu CH, Hou H, Yang B, Zhu Y, Zhang X, Zhou J
Nucleic Acids Res (2023) 51 pp. 8909-8924 [ DOI: doi:10.1093/nar/gkad661 Pubmed: 37604686 ]
- 50s ribosomal protein l40e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l18 (21 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l21e (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l24 (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l23 (9 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l47a (9 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 5s rrna (122-mer) (39 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l22 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l30e (10 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l5 (19 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Small ribosomal subunit protein us8 (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s11 (13 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s17 (12 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s19e (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s13 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s12 (15 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l15 (16 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s27ae (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Trna (76-mer) (24 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- Elongation factor 2 (81 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s27e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- 16s rrna (1493-mer) (487 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l31e (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l18ae (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Conserved protein (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l24e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 23s rrna (3000-mer) (980 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s2 (22 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l18e (12 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s24e (10 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s3 (22 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s10 (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s14 type z (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l4 (27 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l2 (24 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l19e (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l6 (20 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l7ae (13 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s6e (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s4e (27 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s28e (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Unknown (103 Da, Ligand)
- 50s ribosomal protein l13 (15 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s5 (22 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s7 (21 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Mrna (5'-r(p*up*up*up*up*up*up*up*up*u)-3') (2 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l10e (18 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l37e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l37ae (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s3ae (21 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Sulfolobus acidocaldarius ribosome small sbunit (Complex from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s17e (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l14e (9 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l15e (20 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l29 (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l34e (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l14 (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s9 (15 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l44e (10 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s15 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l30 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l32e (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l39e (5 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l3 (38 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Phe-phe-phe-phe-phe-phe (901 Da, Protein from Sulfolobus acidocaldarius DSM 639)
- Duf2280 domain-containing protein (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s8e (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s19 (13 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l1 (24 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s4 (19 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8hl2
Q-score: 0.315
Wang YH, Dai H, Zhang L, Wu Y, Wang J, Wang C, Xu CH, Hou H, Yang B, Zhu Y, Zhang X, Zhou J
Nucleic Acids Res (2023) 51 pp. 8909-8924 [ DOI: doi:10.1093/nar/gkad661 Pubmed: 37604686 ]
- 50s ribosomal protein l40e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l18 (21 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l21e (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l24 (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s8 (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l23 (9 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l47a (9 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 5s rrna (122-mer) (39 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l22 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l30e (10 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l5 (19 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s11 (13 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s19e (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s17 (12 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s13 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s27ae (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l15 (16 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Elongation factor 2 (81 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s12 (15 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Trna (76-mer) (24 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s27e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- 16s rrna (1493-mer) (487 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l31e (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l18ae (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Conserved protein (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l24e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 23s rrna (3000-mer) (980 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s3 (22 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l18e (12 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s10 (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s14 type z (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s2 (22 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s24e (10 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l4 (27 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l2 (24 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l19e (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Mrna (5'-r(p*up*up*up*up*up*up*up*up*up*up*up*up*u)-3') (3 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l6 (20 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l7ae (13 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s28e (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s4e (27 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s6e (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Unknown (103 Da, Ligand)
- 50s ribosomal protein l13 (15 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s5 (22 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s7 (21 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l10e (18 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l37e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l37ae (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s3ae (21 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Sulfolobus acidocaldarius ribosome small sbunit (Complex from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s17e (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l14e (9 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l15e (20 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l29 (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l34e (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l14 (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s9 (15 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l44e (10 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s15 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l30 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l32e (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l39e (5 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l3 (38 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Phe-phe-phe-phe-phe-phe (901 Da, Protein from Sulfolobus acidocaldarius DSM 639)
- Duf2280 domain-containing protein (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s8e (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s19 (13 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l1 (24 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s4 (19 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 8hl3
Q-score: 0.28
Wang YH, Dai H, Zhang L, Wu Y, Wang J, Wang C, Xu CH, Hou H, Yang B, Zhu Y, Zhang X, Zhou J
Nucleic Acids Res (2023) 51 pp. 8909-8924 [ DOI: doi:10.1093/nar/gkad661 Pubmed: 37604686 ]
- 50s ribosomal protein l40e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l18 (21 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l21e (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l24 (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s8 (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l23 (9 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l47a (9 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 5s rrna (122-mer) (39 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l22 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l30e (10 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l5 (19 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s11 (13 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s17 (12 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s19e (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s13 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s12 (15 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l15 (16 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Elongation factor 2 (81 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s27ae (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Trna (76-mer) (24 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s27e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- 16s rrna (1493-mer) (487 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l31e (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l18ae (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Conserved protein (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l24e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 23s rrna (3000-mer) (980 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s2 (22 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l18e (12 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s24e (10 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s3 (22 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s10 (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s14 type z (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l4 (27 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l2 (24 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l19e (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Mrna (5'-r(p*up*up*up*up*up*up*up*up*up*up*up*up*u)-3') (3 kDa, RNA from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l6 (20 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l7ae (13 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s6e (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s4e (27 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s28e (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Unknown (103 Da, Ligand)
- 50s ribosomal protein l13 (15 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s5 (22 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s7 (21 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l10e (18 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l37e (6 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l37ae (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s3ae (21 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Sulfolobus acidocaldarius ribosome small sbunit (Complex from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s17e (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l14e (9 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l15e (20 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l29 (7 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l34e (8 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l14 (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s9 (15 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l44e (10 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s15 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l30 (17 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l32e (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l39e (5 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l3 (38 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- Phe-phe-phe-phe-phe-phe (901 Da, Protein from Sulfolobus acidocaldarius DSM 639)
- Duf2280 domain-containing protein (11 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s8e (14 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s19 (13 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 50s ribosomal protein l1 (24 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
- 30s ribosomal protein s4 (19 kDa, Protein from Sulfolobus acidocaldarius DSM 639)
Cryo-EM structure of a RAS/RAF complex (state 1)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 8dgs
Q-score: 0.261
Park E, Rawson S, Schmoker A, Kim BW, Oh S, Song K, Jeon H, Eck MJ
Nat Commun (2023) 14 pp. 4580-4580 [ DOI: doi:10.1038/s41467-023-40299-6 Pubmed: 37516774 ]
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- 14-3-3 protein zeta (28 kDa, Protein from Spodoptera exigua)
- Kinase complex state-1 (225 kDa, Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Gtpase kras isoform x2 (21 kDa, Protein from Homo sapiens)
- Dual specificity mitogen-activated protein kinase kinase 1 (45 kDa, Protein from Homo sapiens)
- Serine/threonine-protein kinase b-raf (89 kDa, Protein from Homo sapiens)
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- 5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide (456 Da, Ligand)
- Zinc ion (65 Da, Ligand)
Cryo-EM structure of a RAS/RAF complex (state 2)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8dgt
Q-score: 0.274
Park E, Rawson S, Schmoker A, Kim BW, Oh S, Song K, Jeon H, Eck MJ
Nat Commun (2023) 14 pp. 4580-4580 [ DOI: doi:10.1038/s41467-023-40299-6 Pubmed: 37516774 ]
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- 14-3-3 protein zeta (28 kDa, Protein from Spodoptera exigua)
- Kinase complex state-1 (225 kDa, Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Gtpase kras isoform x2 (21 kDa, Protein from Homo sapiens)
- Dual specificity mitogen-activated protein kinase kinase 1 (45 kDa, Protein from Homo sapiens)
- Serine/threonine-protein kinase b-raf (89 kDa, Protein from Homo sapiens)
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- 5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide (456 Da, Ligand)
- Zinc ion (65 Da, Ligand)