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sample_name:"Eukaryotic translation initiation factor 3 subunit F"
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Cryo-EM structure of the human 43S ribosome with PDCD4

Release date: May 1, 2024
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8xxn
Q-score: 0.374

Ye X, Huang Z, Li Y, Wang M, Meng W, Miao M, Cheng J

Cell Res (2024) [ DOI: doi:10.1038/s41422-024-00962-z Pubmed: 38641729 ]

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Structure of a human 48S translation initiation complex with eIF4F and eIF4A

Release date: Feb. 7, 2024
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8oz0
Q-score: 0.391

Brito Querido J, Sokabe M, Diaz-Lopez I, Gordiyenko Y, Fraser CS, Ramakrishnan V

Nat Struct Mol Biol (2024) 31 pp. 455-464 [ DOI: doi:10.1038/s41594-023-01196-0 Pubmed: 38287194 ]

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MERS-CoV Nsp1 bound to the human 43S pre-initiation complex

Release date: Oct. 18, 2023
Resolution: 2.65 Å
EM Method: Single-particle
Fitted PDBs: 8ppl
Q-score: 0.427

Schubert K, Karousis ED, Ban I, Lapointe CP, Leibundgut M, Baumlin E, Kummerant E, Scaiola A, Schonhut T, Ziegelmuller J, Puglisi JD, Muhlemann O, Ban N

Mol Cell (2023) 83 pp. 3546-3557.e8 [ DOI: doi:10.1016/j.molcel.2023.09.002 Pubmed: 37802027 ]

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Structure of the human 48S initiation complex in open state (h48S AUG open)

Release date: May 11, 2022
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 7qp6
Q-score: 0.233

Yi SH, Petrychenko V, Schliep JE, Goyal A, Linden A, Chari A, Urlaub H, Stark H, Rodnina MV, Adio S, Fischer N

Nucleic Acids Res (2022) 50 pp. 5282-5298 [ Pubmed: 35489072 DOI: doi:10.1093/nar/gkac283 ]

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Structure of the human 48S initiation complex in closed state (h48S AUG closed)

Release date: May 11, 2022
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7qp7
Q-score: 0.337

Yi SH, Petrychenko V, Schliep JE, Goyal A, Linden A, Chari A, Urlaub H, Stark H, Rodnina MV, Adio S, Fischer N

Nucleic Acids Res (2022) 50 pp. 5282-5298 [ Pubmed: 35489072 DOI: doi:10.1093/nar/gkac283 ]

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Structure of a human ABCE1-bound 43S pre-initiation complex - State III

Release date: Oct. 14, 2020
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7a09
Q-score: 0.399

Kratzat H, Mackens-Kiani T, Ameismeier M, Potocnjak M, Cheng J, Dacheux E, Namane A, Berninghausen O, Herzog F, Fromont-Racine M, Becker T, Beckmann R

EMBO J (2021) 40 pp. e105179-e105179 [ Pubmed: 33289941 DOI: doi:10.15252/embj.2020105179 ]

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Structure of a human ABCE1-bound 43S pre-initiation complex - State II

Release date: Oct. 7, 2020
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6zvj
Q-score: 0.365

Kratzat H, Mackens-Kiani T, Ameismeier M, Potocnjak M, Cheng J, Dacheux E, Namane A, Berninghausen O, Herzog F, Fromont-Racine M, Becker T, Beckmann R

EMBO J (2021) 40 pp. e105179-e105179 [ Pubmed: 33289941 DOI: doi:10.15252/embj.2020105179 ]

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Structure of a human 48S translational initiation complex

Release date: Sept. 23, 2020
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6zmw
Q-score: 0.293

Brito Querido J, Sokabe M, Kraatz S, Gordiyenko Y, Skehel JM, Fraser CS, Ramakrishnan V

Science (2020) 369 pp. 1220-1227 [ DOI: doi:10.1126/science.aba4904 Pubmed: 32883864 ]

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Structure of a human 48S translational initiation complex - eIF3

Release date: Sept. 16, 2020
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6ybd
Q-score: 0.416

Brito Querido J, Sokabe M, Kraatz S, Gordiyenko Y, Skehel JM, Fraser CS, Ramakrishnan V

Science (2020) 369 pp. 1220-1227 [ DOI: doi:10.1126/science.aba4904 Pubmed: 32883864 ]

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SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 1

Release date: July 29, 2020
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6zon
Q-score: 0.383

Thoms M, Buschauer R, Ameismeier M, Koepke L, Denk T, Hirschenberger M, Kratzat H, Hayn M, Mackens-Kiani T, Cheng J, Straub JH, Sturzel CM, Frohlich T, Berninghausen O, Becker T, Kirchhoff F, Sparrer KMJ, Beckmann R

Science (2020) 369 pp. 1249-1255 [ DOI: doi:10.1126/science.abc8665 Pubmed: 32680882 ]

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