EMDB < Search results

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

Do data resources managed by EMBL-EBI and our collaborators make a difference to your work? Please take 10 minutes to fill in our annual user survey, and help us make the case for why sustaining open data resources is critical for life sciences research.

Edit your search query here and hit Return to execute it:

sample_name:"Cold sensitive U2 snRNA suppressor 1"

Sort by: Download

Showing 1 - 7 of 7. Page 1 of 1

Display: Statistics

Download

Select database:

EMDB [7]

Format:

Select the script type:

Shell (Unix-based) Batch (Windows-based)

Preview first 10

EMD-13028

Download Map 3D View

The U2 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1)

Release date: Aug. 11, 2021
Resolution: 9.0 Å
EM Method: Single-particle
Fitted PDBs: 7oqb
Q-score: 0.133

Zhang Z, Rigo N, Dybkov O, Fourmann JB, Will CL, Kumar V, Urlaub H, Stark H, Luhrmann R

Nature (2021) 596 pp. 296-300 [ Pubmed: 34349264 DOI: doi:10.1038/s41586-021-03789-5 ]

Sample:

Pre-mrna-splicing factor prp9 (63 kDa, Protein from Baker's yeast)
Rds3 complex subunit 10 (9 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein sm d3 (11 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein sm d1 (16 kDa, Protein from Baker's yeast)
Act1 pre-mrna (delta-bs-a) (101 kDa, RNA from Baker's yeast)
Small nuclear ribonucleoprotein e (10 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein g (8 kDa, Protein from Baker's yeast)
Pre-mrna-processing atp-dependent rna helicase prp5 (96 kDa, Protein from Baker's yeast)
U2 snrna (376 kDa, RNA from Baker's yeast)
Pre-mrna-splicing factor rds3 (12 kDa, Protein from Baker's yeast)
U2 snrnp component hsh155 (110 kDa, Protein from Baker's yeast)
Cold sensitive u2 snrna suppressor 1 (50 kDa, Protein from Baker's yeast)
U2 small nuclear ribonucleoprotein a' (27 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor prp21 (33 kDa, Protein from Baker's yeast)
Protein hsh49 (24 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor prp11 (31 kDa, Protein from Baker's yeast)
U2 small nuclear ribonucleoprotein b'' (12 kDa, Protein from Baker's yeast)
S. cerevisiae spliceosomal pre-a complex (Complex from Saccharomyces cerevisiae)
Small nuclear ribonucleoprotein-associated protein b (22 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein sm d2 (12 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor rse1 (153 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein f (9 kDa, Protein from Baker's yeast)

[Show more]

EMD-13033

Download Map 3D View

Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1)

Release date: Aug. 11, 2021
Resolution: 5.9 Å
EM Method: Single-particle
Fitted PDBs: 7oqe
Q-score: 0.121

Zhang Z, Rigo N, Dybkov O, Fourmann JB, Will CL, Kumar V, Urlaub H, Stark H, Luhrmann R

Nature (2021) 596 pp. 296-300 [ Pubmed: 34349264 DOI: doi:10.1038/s41586-021-03789-5 ]

Sample:

Pre-mrna-splicing factor prp9 (63 kDa, Protein from Baker's yeast)
U1 small nuclear ribonucleoprotein c (27 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein sm d3 (11 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein sm d1 (16 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein e (10 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein g (8 kDa, Protein from Baker's yeast)
U1 snrna (182 kDa, RNA from Baker's yeast)
Pre-mrna-processing atp-dependent rna helicase prp5 (96 kDa, Protein from Baker's yeast)
U2 snrna (376 kDa, RNA from Baker's yeast)
U1 small nuclear ribonucleoprotein component snu71 (71 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor rds3 (12 kDa, Protein from Baker's yeast)
Protein nam8 (57 kDa, Protein from Baker's yeast)
U2 snrnp component hsh155 (110 kDa, Protein from Baker's yeast)
56 kda u1 small nuclear ribonucleoprotein component (56 kDa, Protein from Baker's yeast)
Cold sensitive u2 snrna suppressor 1 (50 kDa, Protein from Baker's yeast)
U2 small nuclear ribonucleoprotein a' (27 kDa, Protein from Baker's yeast)
U1 small nuclear ribonucleoprotein component prp42 (65 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor prp21 (33 kDa, Protein from Baker's yeast)
U1 small nuclear ribonucleoprotein a (34 kDa, Protein from Baker's yeast)
U1 small nuclear ribonucleoprotein 70 kda homolog (34 kDa, Protein from Baker's yeast)
Protein luc7 (30 kDa, Protein from Baker's yeast)
Pre-mrna-processing protein prp40 (69 kDa, Protein from Baker's yeast)
Protein hsh49 (24 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor prp11 (31 kDa, Protein from Baker's yeast)
Pre-mrna-processing factor 39 (74 kDa, Protein from Baker's yeast)
U2 small nuclear ribonucleoprotein b'' (12 kDa, Protein from Baker's yeast)
Rds3 complex subunit 10 (10 kDa, Protein from Baker's yeast)
S. cerevisiae spliceosomal pre-a complex (Complex from Saccharomyces cerevisiae)
Small nuclear ribonucleoprotein-associated protein b (22 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein sm d2 (12 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor rse1 (153 kDa, Protein from Baker's yeast)
Act1 pre-mrna (delta bs-a) (111 kDa, RNA from Baker's yeast)
Small nuclear ribonucleoprotein f (9 kDa, Protein from Baker's yeast)

[Show more]

EMD-6972

Download Map 3D View

Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.4~4.6 angstrom (tri-snRNP and U2 snRNP Part)

Release date: Aug. 29, 2018
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 5zwm
Q-score: 0.162

Bai R, Wan R, Yan C, Lei J, Shi Y

Science (2018) 360 pp. 1423-1429 [ DOI: doi:10.1126/science.aau0325 Pubmed: 29794219 ]

Sample:

Guanosine-5'-triphosphate (523 Da, Ligand)
U2 snrnp component ist3 (17 kDa, Protein from Baker's yeast)
66 kda u4/u6.u5 small nuclear ribonucleoprotein component (66 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein g (8 kDa, Protein from Baker's yeast)
Rds3 complex subunit 10 (10 kDa, Protein from Baker's yeast)
U4/u6 small nuclear ribonucleoprotein prp4 (52 kDa, Protein from Baker's yeast)
Yeast fully assembled spliceosomal pre-b complex before activation (Cell from Saccharomyces cerevisiae)
Spliceosomal protein dib1 (16 kDa, Protein from Baker's yeast)
Protein hsh49 (24 kDa, Protein from Baker's yeast)
Pre-mrna-bps (13 kDa, RNA from Saccharomyces cerevisiae S288c)
Zinc ion (65 Da, Ligand)
U6 snrna (35 kDa, RNA from Saccharomyces cerevisiae S288c)
U2 snrna (376 kDa, RNA from Saccharomyces cerevisiae S288c)
Small nuclear ribonucleoprotein-associated protein b (22 kDa, Protein from Baker's yeast)
U2 small nuclear ribonucleoprotein a' (27 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor prp21 (33 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor snu114 (114 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein sm d3 (11 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein e (10 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein sm d2 (12 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein f (9 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor cwc26 (30 kDa, Protein from Baker's yeast)
Cold sensitive u2 snrna suppressor 1 (50 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor prp9 (63 kDa, Protein from Baker's yeast)
U6 snrna-associated sm-like protein lsm6 (9 kDa, Protein from Baker's yeast)
13 kda ribonucleoprotein-associated protein (13 kDa, Protein from Baker's yeast)
U4 snrna (51 kDa, RNA from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor 6 (104 kDa, Protein from Baker's yeast)
U6 snrna-associated sm-like protein lsm8 (12 kDa, Protein from Baker's yeast)
Pre-mrna leakage protein 1 (23 kDa, Protein from Baker's yeast)
U5 snrna (68 kDa, RNA from Saccharomyces cerevisiae S288c)
U2 small nuclear ribonucleoprotein b'' (12 kDa, Protein from Baker's yeast)
U6 snrna-associated sm-like protein lsm2 (11 kDa, Protein from Baker's yeast)
Pre-mrna-splicing helicase brr2 (246 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor rse1 (153 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor prp11 (29 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein sm d1 (16 kDa, Protein from Baker's yeast)
U6 snrna-associated sm-like protein lsm7 (13 kDa, Protein from Baker's yeast)
U6 snrna-associated sm-like protein lsm4 (21 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor rds3 (12 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor 8 (279 kDa, Protein from Baker's yeast)
U2 snrnp component hsh155 (110 kDa, Protein from Baker's yeast)
Magnesium ion (24 Da, Ligand)
U6 snrna-associated sm-like protein lsm3 (10 kDa, Protein from Baker's yeast)
U4/u6 small nuclear ribonucleoprotein prp3 (55 kDa, Protein from Baker's yeast)
U6 snrna-associated sm-like protein lsm5 (10 kDa, Protein from Baker's yeast)
Pre-mrna-processing factor 31 (56 kDa, Protein from Baker's yeast)

[Show more]

EMD-6974

Download Map 3D View

Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom

Release date: Aug. 29, 2018
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 5zwo
Q-score: 0.191

Bai R, Wan R, Yan C, Lei J, Shi Y

Science (2018) 360 pp. 1423-1429 [ DOI: doi:10.1126/science.aau0325 Pubmed: 29794219 ]

Sample:

U2 small nuclear ribonucleoprotein b'' (12 kDa, Protein from Saccharomyces cerevisiae S288c)
U2 snrna (376 kDa, RNA from Saccharomyces cerevisiae S288c)
Small nuclear ribonucleoprotein sm d3 (11 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor 38 (27 kDa, Protein from Saccharomyces cerevisiae S288c)
Small nuclear ribonucleoprotein sm d2 (12 kDa, Protein from Saccharomyces cerevisiae S288c)
U6 snrna-associated sm-like protein lsm4 (21 kDa, Protein from Saccharomyces cerevisiae S288c)
U2 snrnp component ist3 (17 kDa, Protein from Saccharomyces cerevisiae S288c)
Protein hsh49 (24 kDa, Protein from Saccharomyces cerevisiae S288c)
U4/u6 small nuclear ribonucleoprotein prp4 (52 kDa, Protein from Saccharomyces cerevisiae S288c)
U6 snrna (35 kDa, RNA from Saccharomyces cerevisiae S288c)
Spliceosomal protein dib1 (16 kDa, Protein from Saccharomyces cerevisiae S288c)
Small nuclear ribonucleoprotein sm d1 (16 kDa, Protein from Saccharomyces cerevisiae S288c)
Small nuclear ribonucleoprotein e (10 kDa, Protein from Saccharomyces cerevisiae S288c)
U6 snrna-associated sm-like protein lsm5 (10 kDa, Protein from Saccharomyces cerevisiae S288c)
U2 snrnp component hsh155 (110 kDa, Protein from Saccharomyces cerevisiae S288c)
Guanosine-5'-triphosphate (523 Da, Ligand)
U6 snrna-associated sm-like protein lsm6 (9 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna leakage protein 1 (23 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor prp11 (29 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna (19 kDa, RNA from Saccharomyces cerevisiae S288c)
U6 snrna-associated sm-like protein lsm2 (11 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor rds3 (12 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor 8 (279 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor rse1 (153 kDa, Protein from Saccharomyces cerevisiae S288c)
66 kda u4/u6.u5 small nuclear ribonucleoprotein component (66 kDa, Protein from Saccharomyces cerevisiae S288c)
U5 snrna (68 kDa, RNA from Saccharomyces cerevisiae S288c)
Small nuclear ribonucleoprotein-associated protein b (22 kDa, Protein from Saccharomyces cerevisiae S288c)
Rds3 complex subunit 10 (10 kDa, Protein from Saccharomyces cerevisiae S288c)
U6 snrna-associated sm-like protein lsm7 (13 kDa, Protein from Saccharomyces cerevisiae S288c)
Cold sensitive u2 snrna suppressor 1 (50 kDa, Protein from Saccharomyces cerevisiae S288c)
U4 snrna (51 kDa, RNA from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor 6 (104 kDa, Protein from Saccharomyces cerevisiae S288c)
Small nuclear ribonucleoprotein f (9 kDa, Protein from Saccharomyces cerevisiae S288c)
U6 snrna-associated sm-like protein lsm3 (10 kDa, Protein from Saccharomyces cerevisiae S288c)
Yeast fully assembled spliceosomal b complex before activation (Cell from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing helicase brr2 (246 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor spp381 (33 kDa, Protein from Saccharomyces cerevisiae S288c)
U2 small nuclear ribonucleoprotein a' (27 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-processing factor 31 (56 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor prp9 (63 kDa, Protein from Saccharomyces cerevisiae S288c)
U4/u6 small nuclear ribonucleoprotein prp3 (55 kDa, Protein from Saccharomyces cerevisiae S288c)
Small nuclear ribonucleoprotein g (8 kDa, Protein from Saccharomyces cerevisiae S288c)
Magnesium ion (24 Da, Ligand)
U6 snrna-associated sm-like protein lsm8 (12 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor cwc26 (30 kDa, Protein from Saccharomyces cerevisiae S288c)
23 kda u4/u6.u5 small nuclear ribonucleoprotein component (22 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor prp21 (33 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor snu114 (114 kDa, Protein from Saccharomyces cerevisiae S288c)
13 kda ribonucleoprotein-associated protein (13 kDa, Protein from Saccharomyces cerevisiae S288c)

[Show more]

EMD-4364

Download Map 3D View

Prespliceosome structure provides insight into spliceosome assembly and regulation (map A2)

Release date: Aug. 22, 2018
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6g90
Q-score: 0.152

Plaschka C, Lin PC, Charenton C, Nagai K

Nature (2018) 559 pp. 419-422 [ Pubmed: 29995849 DOI: doi:10.1038/s41586-018-0323-8 ]

Sample:

Pre-mrna-splicing factor prp9 (63 kDa, Protein from Baker's yeast)
Prespliceosome a complex (1 MDa, Complex from Saccharomyces cerevisiae)
Yeast ubc4 pre-mrna (mutant) (12 kDa, RNA from Saccharomyces cerevisiae)
U2 snrna (45 kDa, RNA from Saccharomyces cerevisiae)
Small nuclear ribonucleoprotein sm d1 (16 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor prp11,pre-mrna-splicing factor prp11,pre-mrna-splicing factor prp11 (29 kDa, Protein from Baker's yeast)
Zinc ion (65 Da, Ligand)
U1 small nuclear ribonucleoprotein component prp42 (65 kDa, Protein from Baker's yeast)
U1 snrna,u1 snrna,u1 snrna,u1 snrna,u1 snrna (126 kDa, RNA from Saccharomyces cerevisiae)
56 kda u1 small nuclear ribonucleoprotein component (56 kDa, Protein from Baker's yeast)
Cold sensitive u2 snrna suppressor 1 (50 kDa, Protein from Baker's yeast)
U2 small nuclear ribonucleoprotein a' (27 kDa, Protein from Baker's yeast)
U1 small nuclear ribonucleoprotein 70 kda homolog,u1 small nuclear ribonucleoprotein 70 kda homolog,u1 small nuclear ribonucleoprotein 70 kda homolog (33 kDa, Protein from Baker's yeast)
Rds3 complex subunit 10 (10 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor prp21 (33 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein g (8 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein e (10 kDa, Protein from Baker's yeast)
U1 small nuclear ribonucleoprotein c (27 kDa, Protein from Baker's yeast)
Protein nam8 (57 kDa, Protein from Baker's yeast)
Protein luc7,protein luc7,protein luc7 (28 kDa, Protein from Baker's yeast)
Pre-mrna-processing factor 39 (74 kDa, Protein from Baker's yeast)
U2 small nuclear ribonucleoprotein b'' (12 kDa, Protein from Baker's yeast)
Unknown (4 kDa, Protein from Saccharomyces cerevisiae)
Small nuclear ribonucleoprotein-associated protein b (22 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein sm d2 (12 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor rds3 (12 kDa, Protein from Baker's yeast)
U2 snrnp component hsh155 (110 kDa, Protein from Baker's yeast)
Protein hsh49 (24 kDa, Protein from Baker's yeast)
U1 small nuclear ribonucleoprotein component snu71 (71 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor rse1 (153 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein f (9 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein sm d3 (11 kDa, Protein from Baker's yeast)
U1 small nuclear ribonucleoprotein a,u1 small nuclear ribonucleoprotein a,u1 small nuclear ribonucleoprotein a,u1 small nuclear ribonucleoprotein a,u1 small nuclear ribonucleoprotein a (33 kDa, Protein from Baker's yeast)

[Show more]

EMD-3683

Download Map 3D View Raw data

Structure of a pre-catalytic spliceosome (B2 map)

Release date: May 31, 2017
Resolution: 7.2 Å
EM Method: Single-particle
Fitted PDBs: 5nrl
Q-score: 0.117

Plaschka C, Lin PC, Nagai K

Nature (2017) 546 pp. 617-621 [ DOI: doi:10.1038/nature22799 Pubmed: 28530653 ]

Sample:

Pre-mrna-splicing factor prp9 (63 kDa, Protein from Baker's yeast)
Yeast ubc4 gene for ubiquitin-conjugating enzyme (30 kDa, RNA from Saccharomyces cerevisiae)
U6 snrna-associated sm-like protein lsm3 (10 kDa, Protein from Baker's yeast)
U4/u6 small nuclear ribonucleoprotein prp3 (55 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor 6 (104 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein sm d3 (11 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein sm d1 (16 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein e (10 kDa, Protein from Baker's yeast)
66 kda u4/u6.u5 small nuclear ribonucleoprotein component (66 kDa, Protein from Baker's yeast)
U2 snrna (376 kDa, RNA from Saccharomyces cerevisiae)
Zinc ion (65 Da, Ligand)
U6 snrna-associated sm-like protein lsm7 (13 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein g (8 kDa, Protein from Baker's yeast)
Pre-mrna-processing factor 31 (56 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor spp381 (33 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor 38 (27 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor rds3 (12 kDa, Protein from Baker's yeast)
13 kda ribonucleoprotein-associated protein (13 kDa, Protein from Baker's yeast)
U2 snrnp component hsh155 (110 kDa, Protein from Baker's yeast)
Guanosine-5'-triphosphate (523 Da, Ligand)
Pre-mrna-splicing helicase brr2 (246 kDa, Protein from Baker's yeast)
Cold sensitive u2 snrna suppressor 1 (50 kDa, Protein from Baker's yeast)
U6 snrna-associated sm-like protein lsm5 (10 kDa, Protein from Baker's yeast)
U2 small nuclear ribonucleoprotein a' (27 kDa, Protein from Baker's yeast)
Pre-catalytic b complex spliceosome (2 MDa, Complex from Saccharomyces cerevisiae)
Pre-mrna-splicing factor prp21 (33 kDa, Protein from Baker's yeast)
U5 snrna (68 kDa, RNA from Saccharomyces cerevisiae)
U6 snrna-associated sm-like protein lsm8 (12 kDa, Protein from Baker's yeast)
23 kda u4/u6.u5 small nuclear ribonucleoprotein component (22 kDa, Protein from Baker's yeast)
U6 snrna-associated sm-like protein lsm2 (11 kDa, Protein from Baker's yeast)
Protein hsh49 (24 kDa, Protein from Baker's yeast)
Spliceosomal protein dib1 (16 kDa, Protein from Baker's yeast)
U6 snrna-associated sm-like protein lsm4 (21 kDa, Protein from Baker's yeast)
U6 snrna (35 kDa, RNA from Saccharomyces cerevisiae)
U2 small nuclear ribonucleoprotein b'' (12 kDa, Protein from Baker's yeast)
Rds3 complex subunit 10 (10 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor snu114 (114 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein-associated protein b (22 kDa, Protein from Baker's yeast)
U6 snrna-associated sm-like protein lsm6 (9 kDa, Protein from Baker's yeast)
U4 snrna (51 kDa, RNA from Saccharomyces cerevisiae)
Small nuclear ribonucleoprotein sm d2 (12 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor prp11 (29 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor rse1 (153 kDa, Protein from Baker's yeast)
Unknown (7 kDa, Protein from Saccharomyces cerevisiae)
U4/u6 small nuclear ribonucleoprotein prp4 (52 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein f (9 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor 8 (279 kDa, Protein from Baker's yeast)

[Show more]

EMD-9524

Download Map 3D View

Cryo-EM structure of the activated spliceosome (Bact complex) at 3.5 angstrom resolution

Release date: Sept. 21, 2016
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 5gm6
Q-score: 0.377

Yan C, Wan R, Bai R, Huang G, Shi Y

Science (2016) 353 pp. 904-911 [ Pubmed: 27445306 DOI: doi:10.1126/science.aag0291 ]

Sample:

Pre-mrna-splicing factor atp-dependent rna helicase-like protein prp2 (99 kDa, Protein from Baker's yeast)
Guanosine-5'-triphosphate (523 Da, Ligand)
Pre-mrna-splicing factor clf1 (68 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor slt11 (40 kDa, Protein from Baker's yeast)
Pre-mrna (18 kDa, RNA from Saccharomyces cerevisiae S288c)
U2 snrnp component ist3 (17 kDa, Protein from Baker's yeast)
Pre-mrna-processing factor 19 (56 kDa, Protein from Baker's yeast)
Saccharomyces cerevisiae strain cdrdr_sf_h chromosome vii sequence (68 kDa, RNA from Saccharomyces cerevisiae)
Small nuclear ribonucleoprotein g (8 kDa, Protein from Baker's yeast)
Rds3 complex subunit 10 (10 kDa, Protein from Baker's yeast)
Protein hsh49 (24 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor cwc24 (29 kDa, Protein from Baker's yeast)
Zinc ion (65 Da, Ligand)
Small nuclear ribonucleoprotein sm d2 (11 kDa, Protein from Baker's yeast)
U2 snrna (376 kDa, RNA from Saccharomyces cerevisiae S288c)
Small nuclear ribonucleoprotein-associated protein b (22 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor syf2 (24 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor snu114 (114 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein e (10 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein f (9 kDa, Protein from Baker's yeast)
Pre-mrna-processing protein 45 (42 kDa, Protein from Baker's yeast)
Saccharomyces cerevisiae strain t.52_2h chromosome xii sequence (35 kDa, RNA from Saccharomyces cerevisiae)
Pre-mrna leakage protein 1 (24 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor cwc26 (30 kDa, Protein from Baker's yeast)
Cold sensitive u2 snrna suppressor 1 (50 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein sm d3 (11 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor cwc22 (67 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor cwc21 (15 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor snt309 (20 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor 8 (265 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor cef1 (61 kDa, Protein from Baker's yeast)
Pre-mrna-splicing helicase brr2 (246 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor rse1 (153 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor prp11 (29 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor bud31 (18 kDa, Protein from Baker's yeast)
Small nuclear ribonucleoprotein sm d1 (16 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor syf1 (78 kDa, Protein from Saccharomyces cerevisiae S288c)
Pre-mrna-splicing factor rds3 (12 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor prp46 (50 kDa, Protein from Baker's yeast)
Pre-mrna-processing factor 17 (52 kDa, Protein from Baker's yeast)
Adenosine-5'-diphosphate (427 Da, Ligand)
Pre-mrna (7 kDa, RNA from Saccharomyces cerevisiae S288c)
U2 snrnp component hsh155 (110 kDa, Protein from Baker's yeast)
Magnesium ion (24 Da, Ligand)
Pre-mrna-splicing factor cwc15 (19 kDa, Protein from Baker's yeast)
Pre-mrna-splicing factor cwc2 (38 kDa, Protein from Baker's yeast)
Peptidyl-prolyl isomerase cwc27 (35 kDa, Protein from Baker's yeast)
Bact spliceosomal complex (2 MDa, Complex from Saccharomyces cerevisiae S288c)

[Show more]

Sort by: Download

Showing 1 - 7 of 7. Page 1 of 1

Display: Statistics

Download

Select database:

EMDB [7]

Format:

Select the script type:

Shell (Unix-based) Batch (Windows-based)

Preview first 10

Field: