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CryoEM structure of PN45545 TCR-CD3 in complex with HLA-A2 MAGEA4 (230-239)
Resolution: 2.65 Å
EM Method: Single-particle
Fitted PDBs: 8es8
Q-score: 0.537
Saotome K, Dudgeon D, Colotti K, Moore MJ, Jones J, Zhou Y, Rafique A, Yancopoulos GD, Murphy AJ, Lin JC, Olson WC, Franklin MC
Nat Commun (2023) 14 pp. 2401-2401 [ DOI: doi:10.1038/s41467-023-37532-7 Pubmed: 37100770 ]
- Pn45545 tcr-cd3 complex bound to hla-a2 magea4 (230-239) with anti-beta-2-microglobulin fab (Complex from Homo sapiens)
- Melanoma-associated antigen 4 (1 kDa, Protein from Homo sapiens)
- Mhc class i antigen (32 kDa, Protein from Homo sapiens)
- Beta-2-microglobulin (11 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Pn45545 tcr beta chain (35 kDa, Protein from Homo sapiens)
- T-cell surface glycoprotein cd3 delta chain (19 kDa, Protein from Homo sapiens)
- T-cell surface glycoprotein cd3 epsilon chain (23 kDa, Protein from Homo sapiens)
- T-cell surface glycoprotein cd3 zeta chain (19 kDa, Protein from Homo sapiens)
- Pn45545 tcr alpha chain (30 kDa, Protein from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
- T-cell surface glycoprotein cd3 gamma chain (20 kDa, Protein from Homo sapiens)
CryoEM structure of PN45428 TCR-CD3 in complex with HLA-A2 MAGEA4
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8es9
Q-score: 0.475
Saotome K, Dudgeon D, Colotti K, Moore MJ, Jones J, Zhou Y, Rafique A, Yancopoulos GD, Murphy AJ, Lin JC, Olson WC, Franklin MC
Nat Commun (2023) 14 pp. 2401-2401 [ DOI: doi:10.1038/s41467-023-37532-7 Pubmed: 37100770 ]
- Pn45428 tcr alpha chain (30 kDa, Protein from Homo sapiens)
- Melanoma-associated antigen 4 (1 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Mhc class i antigen (32 kDa, Protein from Homo sapiens)
- T-cell surface glycoprotein cd3 gamma chain (20 kDa, Protein from Homo sapiens)
- Beta-2-microglobulin (11 kDa, Protein from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
- T-cell surface glycoprotein cd3 delta chain (19 kDa, Protein from Homo sapiens)
- Pn45428 tcr beta chain (35 kDa, Protein from Homo sapiens)
- T-cell surface glycoprotein cd3 zeta chain (19 kDa, Protein from Homo sapiens)
- Pn45428 tcr-cd3 complex bound to hla-a2 magea4 (230-239) in the presence of 2m2 fab (Complex from Homo sapiens)
- T-cell surface glycoprotein cd3 epsilon chain (23 kDa, Protein from Homo sapiens)
Structure of a fully assembled T-cell receptor engaging a tumor-associated peptide-MHC I
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 7phr
Q-score: 0.505
Susac L, Vuong MT, Thomas C, von Bulow S, O'Brien-Ball C, Santos AM, Fernandes RA, Hummer G, Tampe R, Davis SJ
Cell (2022) 185 pp. 3201-3213.e19 [ Pubmed: 35985289 DOI: doi:10.1016/j.cell.2022.07.010 ]
- T-cell surface glycoprotein cd3 zeta chain (4 kDa, Protein from Homo sapiens)
- T-cell surface glycoprotein cd3 epsilon chain (15 kDa, Protein from Homo sapiens)
- T-cell receptor alpha chain (27 kDa, Protein from Homo sapiens)
- T-cell surface glycoprotein cd3 gamma chain (13 kDa, Protein from Homo sapiens)
- T-cell surface glycoprotein cd3 delta chain, green fluorescent protein (39 kDa, Protein from Aequorea victoria)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fully assembled t-cell receptor engaging a tumor-associated peptide-mhc i (Complex from Homo sapiens)
- Tumor-associated antigentic peptide gp100 (974 Da, Protein from Homo sapiens)
- Beta-2-microglobulin (11 kDa, Protein from Homo sapiens)
- Hla class i histocompatibility antigen, a alpha chain (35 kDa, Protein from Homo sapiens)
- T-cell receptor beta chain (32 kDa, Protein from Homo sapiens)
Structure of echovirus 18 in complex with neonatal Fc receptor
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7b5f
Q-score: 0.622
Buchta D, Levdansky Y, Fuzik T, Mukhamedova L, Moravcova J, Hrebik D, Andersen JT, Plevka P
To Be Published
- Structure of echovirus 18 in complex with neonatal fc receptor (2 MDa, Complex)
- Echovirus 18 viral protein 4 (7 kDa, Protein from Echovirus E18)
- Echovirus 18 viral protein 1 (32 kDa, Protein from Echovirus E18)
- Igg receptor fcrn large subunit p51 (29 kDa, Protein from Homo sapiens)
- Beta-2-microglobulin (11 kDa, Protein from Homo sapiens)
- Heterodimer of neonatal fc receptor and beta-2-microglobulin (Complex from Homo sapiens)
- Palmitic acid (256 Da, Ligand)
- Echovirus 18 viral protein 2 (28 kDa, Protein from Echovirus E18)
- Guanine (151 Da, Ligand)
- Echovirus 18 native virion (Complex from Echovirus E18)
- Echovirus 18 viral protein 3 (26 kDa, Protein from Echovirus E18)
E30 F-particle in complex with FcRn
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7c9v
Q-score: 0.502
Wang K, Zhu L, Sun Y, Li M, Zhao X, Cui L, Zhang L, Gao GF, Zhai W, Zhu F, Rao Z, Wang X
Nat Commun (2020) 11 pp. 4421-4421 [ Pubmed: 32887891 DOI: doi:10.1038/s41467-020-18251-9 ]
- E30 f-particle in complex with fcrn (Complex)
- Vp1 (33 kDa, Protein from Echovirus E30)
- Vp4 (7 kDa, Protein from Echovirus E30)
- Vp3 (26 kDa, Protein from Echovirus E30)
- Beta-2-microglobulin (11 kDa, Protein from Homo sapiens)
- Myristic acid (228 Da, Ligand)
- Vp2 (28 kDa, Protein from Echovirus E30)
- Echovirus e30 (Complex from Echovirus E30)
- Igg receptor fcrn large subunit p51 (29 kDa, Protein from Homo sapiens)
Cryo-EM structure of Echovirus 6 complexed with its uncoating receptor FcRn at PH 7.4
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6ilm
Q-score: 0.456
Zhao X, Zhang G, Liu S, Chen X, Peng R, Dai L, Qu X, Li S, Song H, Gao Z, Yuan P, Liu Z, Li C, Shang Z, Li Y, Zhang M, Qi J, Wang H, Du N, Wu Y, Bi Y, Gao S, Shi Y, Yan J, Zhang Y, Xie Z, Wei W, Gao GF
Cell (2019) 177 pp. 1553-1565.e16 [ DOI: doi:10.1016/j.cell.2019.04.035 Pubmed: 31104841 ]
- Sphingosine (299 Da, Ligand)
- Capsid protein vp2 (28 kDa, Protein from Echovirus E6)
- Cryo-em structure of echovirus 6 complexed with its uncoating receptor fcrn at ph 7.4 (Complex from Echovirus E6)
- Potassium ion (39 Da, Ligand)
- Capsid protein vp3 (26 kDa, Protein from Echovirus E6)
- Sodium ion (22 Da, Ligand)
- Capsid protein vp4 (7 kDa, Protein from Echovirus E6)
- Capsid protein vp1 (32 kDa, Protein from Echovirus E6)
- Beta-2-microglobulin (11 kDa, Protein from Homo sapiens)
- Igg receptor fcrn large subunit p51 (29 kDa, Protein from Homo sapiens)