human nuclear pre-60S ribosomal particle - State G'
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8ine
Q-score: 0.465
Zhang Y, Liang X, Luo S, Chen Y, Li Y, Ma C, Li N, Gao N
Cell Res (2023) 33 pp. 867-878 [ Pubmed: 37491604 DOI: doi:10.1038/s41422-023-00853-9 ]
- Mki67 fha domain-interacting nucleolar phosphoprotein (34 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
- Human nuclear pre-60s state g' (Complex from Homo sapiens)
- Ribosome biogenesis protein nop53 (54 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- Gtp-binding protein 4 (74 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l29 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l11 (20 kDa, Protein from Homo sapiens)
- Leydig cell tumor 10 kda protein homolog (10 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l14 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l8 (28 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l12 (17 kDa, Protein from Homo sapiens)
- Ribosomal l1 domain-containing protein 1 (55 kDa, Protein from Homo sapiens)
- Zinc finger protein 593 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from Homo sapiens)
- Probable ribosome biogenesis protein rlp24 (19 kDa, Protein from Homo sapiens)
- G protein nucleolar 2 (83 kDa, Protein from Homo sapiens)
- 5.8s rrna (50 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l22 (14 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- 60s ribosomal protein l30 (12 kDa, Protein from Homo sapiens)
- Pescadillo homolog (68 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36 (12 kDa, Protein from Homo sapiens)
- Eukaryotic translation initiation factor 6 (26 kDa, Protein from Homo sapiens)
- 5s rrna (38 kDa, RNA from Homo sapiens)
- Protein llp homolog (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l4 (47 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l6 (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l34 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23a (17 kDa, Protein from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- 60s ribosomal protein l7-like 1 (29 kDa, Protein from Homo sapiens)
- Internal transcribed spacer 2 (11 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
- 28s rrna (1 MDa, RNA from Homo sapiens)
- 60s ribosomal protein l26 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l28 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Homo sapiens)
- Translation machinery-associated protein 16 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l39 (6 kDa, Protein from Homo sapiens)
- Mrna turnover protein 4 homolog (27 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7 (29 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l31 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l19 (23 kDa, Protein from Homo sapiens)
- Ribosome biogenesis protein nsa2 homolog (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l3 (46 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37 (11 kDa, Protein from Homo sapiens)
human nuclear pre-60S ribosomal particle - State F'
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8inf
Q-score: 0.497
Zhang Y, Liang X, Luo S, Chen Y, Li Y, Ma C, Li N, Gao N
Cell Res (2023) 33 pp. 867-878 [ Pubmed: 37491604 DOI: doi:10.1038/s41422-023-00853-9 ]
- Mki67 fha domain-interacting nucleolar phosphoprotein (34 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
- Ribosome biogenesis protein nop53 (54 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- Gtp-binding protein 4 (74 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l29 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l11 (20 kDa, Protein from Homo sapiens)
- Leydig cell tumor 10 kda protein homolog (10 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l14 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l8 (28 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l12 (17 kDa, Protein from Homo sapiens)
- Protein sda1 homolog (80 kDa, Protein from Homo sapiens)
- Ribosomal l1 domain-containing protein 1 (55 kDa, Protein from Homo sapiens)
- Zinc finger protein 593 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from Homo sapiens)
- Probable ribosome biogenesis protein rlp24 (19 kDa, Protein from Homo sapiens)
- G protein nucleolar 2 (83 kDa, Protein from Homo sapiens)
- 5.8s rrna (50 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l22 (14 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- 60s ribosomal protein l30 (12 kDa, Protein from Homo sapiens)
- Pescadillo homolog (68 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36 (12 kDa, Protein from Homo sapiens)
- Eukaryotic translation initiation factor 6 (26 kDa, Protein from Homo sapiens)
- 5s rrna (38 kDa, RNA from Homo sapiens)
- Cryo-em structure of human nuclear pre-60s ribosomal particle - state f' (Complex from Homo sapiens)
- 60s ribosomal protein l4 (47 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l6 (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l34 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23a (17 kDa, Protein from Homo sapiens)
- Protein llp homolog (15 kDa, Protein from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- 60s ribosomal protein l7-like 1 (29 kDa, Protein from Homo sapiens)
- 28s rrna (1 MDa, RNA from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
- Internal transcribed spacer 2 (23 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l26 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l28 (15 kDa, Protein from Homo sapiens)
- Uncharacterized protein c11orf98 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l10a (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Homo sapiens)
- Translation machinery-associated protein 16 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l39 (6 kDa, Protein from Homo sapiens)
- Mrna turnover protein 4 homolog (27 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7 (29 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l31 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l19 (23 kDa, Protein from Homo sapiens)
- Ribosome biogenesis protein nsa2 homolog (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l3 (46 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37 (11 kDa, Protein from Homo sapiens)
human nuclear pre-60S ribosomal particle - State C'
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 8ipx
Q-score: 0.292
Zhang Y, Liang X, Luo S, Chen Y, Li Y, Ma C, Li N, Gao N
Cell Res (2023) 33 pp. 867-878 [ Pubmed: 37491604 DOI: doi:10.1038/s41422-023-00853-9 ]
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Mki67 fha domain-interacting nucleolar phosphoprotein (34 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
- Ribosome biogenesis protein nop53 (54 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- Gtp-binding protein 4 (74 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l29 (17 kDa, Protein from Homo sapiens)
- Cryo-em structure of human nuclear pre-60s ribosomal particle - state c' (Complex from Homo sapiens)
- 60s ribosomal protein l11 (20 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l14 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l8 (28 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l12 (17 kDa, Protein from Homo sapiens)
- Ribosomal l1 domain-containing protein 1 (55 kDa, Protein from Homo sapiens)
- Zinc finger protein 593 (15 kDa, Protein from Homo sapiens)
- 28s rrna (1 MDa, RNA from Homo sapiens)
- Probable ribosome biogenesis protein rlp24 (19 kDa, Protein from Homo sapiens)
- G protein nucleolar 2 (83 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from Homo sapiens)
- 5.8s rrna (50 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l22 (14 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l30 (12 kDa, Protein from Homo sapiens)
- Pescadillo homolog (68 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36 (12 kDa, Protein from Homo sapiens)
- Eukaryotic translation initiation factor 6 (26 kDa, Protein from Homo sapiens)
- Protein llp homolog (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l4 (47 kDa, Protein from Homo sapiens)
- Its2 (11 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l6 (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l34 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- Coiled-coil domain-containing protein 86 (40 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23a (17 kDa, Protein from Homo sapiens)
- Notchless protein homolog 1 (53 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7-like 1 (29 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l26 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l28 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- 5s rna (38 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l39 (6 kDa, Protein from Homo sapiens)
- Mrna turnover protein 4 homolog (27 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7 (29 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l31 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- Ribosome biogenesis protein nsa2 homolog (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l19 (23 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein-like 3 (62 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l3 (46 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37 (11 kDa, Protein from Homo sapiens)
human nuclear pre-60S ribosomal particle - State D'
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8ipy
Q-score: 0.455
Zhang Y, Liang X, Luo S, Chen Y, Li Y, Ma C, Li N, Gao N
Cell Res (2023) 33 pp. 867-878 [ Pubmed: 37491604 DOI: doi:10.1038/s41422-023-00853-9 ]
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Mki67 fha domain-interacting nucleolar phosphoprotein (34 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
- Ribosome biogenesis protein nop53 (54 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- Gtp-binding protein 4 (74 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l29 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l11 (20 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l14 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l8 (28 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l12 (17 kDa, Protein from Homo sapiens)
- Protein sda1 homolog (80 kDa, Protein from Homo sapiens)
- Ribosomal l1 domain-containing protein 1 (55 kDa, Protein from Homo sapiens)
- Zinc finger protein 593 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from Homo sapiens)
- Probable ribosome biogenesis protein rlp24 (19 kDa, Protein from Homo sapiens)
- G protein nucleolar 2 (83 kDa, Protein from Homo sapiens)
- 5.8s rrna (50 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l22 (14 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l30 (12 kDa, Protein from Homo sapiens)
- Pescadillo homolog (68 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36 (12 kDa, Protein from Homo sapiens)
- Eukaryotic translation initiation factor 6 (26 kDa, Protein from Homo sapiens)
- Protein llp homolog (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l4 (47 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l6 (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l34 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
- 28s rrna (1 MDa, RNA from Homo sapiens)
- Coiled-coil domain-containing protein 86 (40 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23a (17 kDa, Protein from Homo sapiens)
- Notchless protein homolog 1 (53 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7-like 1 (29 kDa, Protein from Homo sapiens)
- Cryo-em structure of human nuclear pre-60s ribosomal particle - state d' (Complex from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
- Its2 (31 kDa, RNA from Homo sapiens)
- 5s rrna (38 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l26 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l28 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l39 (6 kDa, Protein from Homo sapiens)
- Mrna turnover protein 4 homolog (27 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7 (29 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l31 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- Ribosome biogenesis protein nsa2 homolog (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l19 (23 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein-like 3 (62 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l3 (46 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37 (11 kDa, Protein from Homo sapiens)
human nuclear pre-60S ribosomal particle - State B'
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8ir3
Q-score: 0.439
Zhang Y, Liang X, Luo S, Chen Y, Li Y, Ma C, Li N, Gao N
Cell Res (2023) 33 pp. 867-878 [ Pubmed: 37491604 DOI: doi:10.1038/s41422-023-00853-9 ]
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Mki67 fha domain-interacting nucleolar phosphoprotein (34 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
- Ribosome biogenesis protein nop53 (54 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- Gtp-binding protein 4 (74 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l11 (20 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l14 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l12 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l8 (28 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- Ribosome production factor 2 homolog (35 kDa, Protein from Homo sapiens)
- Ribosomal l1 domain-containing protein 1 (55 kDa, Protein from Homo sapiens)
- Zinc finger protein 593 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from Homo sapiens)
- Probable ribosome biogenesis protein rlp24 (19 kDa, Protein from Homo sapiens)
- G protein nucleolar 2 (83 kDa, Protein from Homo sapiens)
- 28s rrna (1 MDa, RNA from Homo sapiens)
- 5.8s rrna (50 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l22 (14 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l30 (12 kDa, Protein from Homo sapiens)
- Pescadillo homolog (68 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36 (12 kDa, Protein from Homo sapiens)
- Eukaryotic translation initiation factor 6 (26 kDa, Protein from Homo sapiens)
- Protein llp homolog (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l4 (47 kDa, Protein from Homo sapiens)
- Its2 (11 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l6 (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l34 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- Coiled-coil domain-containing protein 86 (40 kDa, Protein from Homo sapiens)
- Cryo-em structure of human nuclear pre-60s ribosomal particle - state b (Complex from Homo sapiens)
- 60s ribosomal protein l23a (17 kDa, Protein from Homo sapiens)
- Notchless protein homolog 1 (53 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7-like 1 (29 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l26 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l28 (15 kDa, Protein from Homo sapiens)
- 5s rna (38 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l39 (6 kDa, Protein from Homo sapiens)
- Mrna turnover protein 4 homolog (27 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7 (29 kDa, Protein from Homo sapiens)
- Ribosome biogenesis regulatory protein homolog (41 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l31 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- Ribosome biogenesis protein nsa2 homolog (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l19 (23 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein-like 3 (62 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l3 (46 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37 (11 kDa, Protein from Homo sapiens)
Human nucleolar pre-60S ribosomal subunit (State A1) - Composite map
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 8fkp
Q-score: 0.521
Science (2023) 381 pp. eadh3892-eadh3892 [ Pubmed: 37410842 DOI: doi:10.1126/science.adh3892 ]
- Human nucleolar pre-60s ribosomal subunit (state a1) (Complex from Homo sapiens)
- Mki67 fha domain-interacting nucleolar phosphoprotein (34 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
- Nucleolar protein 16 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- Protein mak16 homolog (35 kDa, Protein from Homo sapiens)
- Wd repeat-containing protein 74 (42 kDa, Protein from Homo sapiens)
- Probable rrna-processing protein ebp2 (34 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- Gtp-binding protein 4 (74 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Its2 rrna (376 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l14 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- Ribosome biogenesis protein bop1 (83 kDa, Protein from Homo sapiens)
- Pre-rrna 2'-o-ribose rna methyltransferase ftsj3 (96 kDa, Protein from Homo sapiens)
- 5.8s rrna (50 kDa, RNA from Homo sapiens)
- Ribosomal rna processing protein 1 homolog a (52 kDa, Protein from Homo sapiens)
- Ribosomal l1 domain-containing protein 1 (55 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from Homo sapiens)
- Probable ribosome biogenesis protein rlp24 (19 kDa, Protein from Homo sapiens)
- 28s rrna (1 MDa, RNA from Homo sapiens)
- Pescadillo homolog (68 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36 (12 kDa, Protein from Homo sapiens)
- Eukaryotic translation initiation factor 6 (26 kDa, Protein from Homo sapiens)
- Suppressor of swi4 1 homolog (53 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l4 (47 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l6 (32 kDa, Protein from Homo sapiens)
- Rrp15-like protein (31 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23a (17 kDa, Protein from Homo sapiens)
- Atp-dependent rna helicase ddx18 (75 kDa, Protein from Homo sapiens)
- Iron/sulfur cluster (351 Da, Ligand)
- 60s ribosomal protein l3 (46 kDa, Protein from Homo sapiens)
- Ribosome production factor 1 (40 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7-like 1 (29 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l26 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Homo sapiens)
- Surfeit locus protein 6 (41 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7 (29 kDa, Protein from Homo sapiens)
- Ribosome biogenesis regulatory protein homolog (41 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein-like 3 (62 kDa, Protein from Homo sapiens)
- Ribosome biogenesis protein brx1 homolog (41 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l37 (11 kDa, Protein from Homo sapiens)
Human nucleolar pre-60S ribosomal subunit (State A2) - Composite map
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 8fkq
Q-score: 0.525
Science (2023) 381 pp. eadh3892-eadh3892 [ Pubmed: 37410842 DOI: doi:10.1126/science.adh3892 ]
- 60s ribosomal protein l21 (18 kDa, Protein from human)
- 60s ribosomal protein l14 (23 kDa, Protein from human)
- 60s ribosomal protein l26 (17 kDa, Protein from human)
- Ribosome biogenesis protein bop1 (83 kDa, Protein from human)
- 60s ribosomal protein l37 (11 kDa, Protein from human)
- Pre-rrna 2'-o-ribose rna methyltransferase ftsj3 (96 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- 60s ribosomal protein l6 (32 kDa, Protein from human)
- Nucleolar protein 16 (21 kDa, Protein from human)
- 60s ribosomal protein l7-like 1 (29 kDa, Protein from human)
- Pescadillo homolog (68 kDa, Protein from human)
- 28s rrna (1 MDa, RNA from human)
- 60s ribosomal protein l3 (46 kDa, Protein from human)
- 60s ribosomal protein l35a (12 kDa, Protein from human)
- Probable ribosome biogenesis protein rlp24 (19 kDa, Protein from human)
- Suppressor of swi4 1 homolog (53 kDa, Protein from human)
- 60s ribosomal protein l15 (24 kDa, Protein from human)
- Mki67 fha domain-interacting nucleolar phosphoprotein (34 kDa, Protein from human)
- 60s ribosomal protein l23a (17 kDa, Protein from human)
- Rrp15-like protein (31 kDa, Protein from human)
- Ribosome biogenesis protein brx1 homolog (41 kDa, Protein from human)
- 60s ribosomal protein l35 (14 kDa, Protein from human)
- 60s ribosomal protein l32 (15 kDa, Protein from human)
- 60s ribosomal protein l18 (21 kDa, Protein from human)
- Human nucleolar pre-60s ribosomal subunit (state a2) (Complex from Homo sapiens)
- 60s ribosomal protein l7 (29 kDa, Protein from human)
- 60s ribosomal protein l7a (30 kDa, Protein from human)
- Ribosome biogenesis regulatory protein homolog (41 kDa, Protein from human)
- Ribosomal l1 domain-containing protein 1 (55 kDa, Protein from human)
- 60s ribosomal protein l13 (24 kDa, Protein from human)
- Probable rrna-processing protein ebp2 (34 kDa, Protein from human)
- 60s ribosomal protein l36 (12 kDa, Protein from human)
- Its2 rrna (376 kDa, RNA from human)
- Surfeit locus protein 6 (41 kDa, Protein from human)
- Atp-dependent rna helicase ddx18 (75 kDa, Protein from human)
- 60s ribosomal protein l18a (20 kDa, Protein from human)
- 60s ribosomal protein l28 (15 kDa, Protein from human)
- 60s ribosomal protein l17 (21 kDa, Protein from human)
- 60s ribosomal protein l13a (23 kDa, Protein from human)
- Gtp-binding protein 4 (74 kDa, Protein from human)
- 5.8s rrna (50 kDa, RNA from human)
- 60s ribosomal protein l23 (14 kDa, Protein from human)
- 60s ribosomal protein l4 (47 kDa, Protein from human)
- Eukaryotic translation initiation factor 6 (26 kDa, Protein from human)
- 60s ribosomal protein l27a (16 kDa, Protein from human)
- Magnesium ion (24 Da, Ligand)
Human nucleolar pre-60S ribosomal subunit (State B1) - Composite map
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 8fkr
Q-score: 0.497
Science (2023) 381 pp. eadh3892-eadh3892 [ Pubmed: 37410842 DOI: doi:10.1126/science.adh3892 ]
- Ribosome production factor 1 (40 kDa, Protein from human)
- 60s ribosomal protein l12 (17 kDa, Protein from human)
- 60s ribosomal protein l21 (18 kDa, Protein from human)
- 60s ribosomal protein l14 (23 kDa, Protein from human)
- 60s ribosomal protein l26 (17 kDa, Protein from human)
- Ribosome biogenesis protein bop1 (83 kDa, Protein from human)
- Ribosome biogenesis protein nsa2 homolog (30 kDa, Protein from human)
- 60s ribosomal protein l37 (11 kDa, Protein from human)
- Ribosomal rna processing protein 1 homolog a (52 kDa, Protein from human)
- Pre-rrna 2'-o-ribose rna methyltransferase ftsj3 (96 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- 60s ribosomal protein l6 (32 kDa, Protein from human)
- Nucleolar protein 16 (21 kDa, Protein from human)
- 60s ribosomal protein l7-like 1 (29 kDa, Protein from human)
- Pescadillo homolog (68 kDa, Protein from human)
- 28s rrna (1 MDa, RNA from human)
- 60s ribosomal protein l3 (46 kDa, Protein from human)
- Human nucleolar pre-60s ribosomal subunit (state b1) (Complex from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from human)
- Wd repeat-containing protein 74 (42 kDa, Protein from human)
- Probable ribosome biogenesis protein rlp24 (19 kDa, Protein from human)
- Suppressor of swi4 1 homolog (53 kDa, Protein from human)
- Mrna turnover protein 4 homolog (27 kDa, Protein from human)
- Potassium ion (39 Da, Ligand)
- 60s ribosomal protein l15 (24 kDa, Protein from human)
- Mki67 fha domain-interacting nucleolar phosphoprotein (34 kDa, Protein from human)
- 60s ribosomal protein l23a (17 kDa, Protein from human)
- Rrp15-like protein (31 kDa, Protein from human)
- Ribosome biogenesis protein brx1 homolog (41 kDa, Protein from human)
- 60s ribosomal protein l35 (14 kDa, Protein from human)
- 60s ribosomal protein l32 (15 kDa, Protein from human)
- Iron/sulfur cluster (351 Da, Ligand)
- 60s ribosomal protein l18 (21 kDa, Protein from human)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- 60s ribosomal protein l7 (29 kDa, Protein from human)
- 60s ribosomal protein l7a (30 kDa, Protein from human)
- Ribosome biogenesis regulatory protein homolog (41 kDa, Protein from human)
- Ribosomal l1 domain-containing protein 1 (55 kDa, Protein from human)
- 60s ribosomal protein l9 (21 kDa, Protein from human)
- 60s ribosomal protein l13 (24 kDa, Protein from human)
- Probable rrna-processing protein ebp2 (34 kDa, Protein from human)
- 60s ribosomal protein l36 (12 kDa, Protein from human)
- Its2 rrna (376 kDa, RNA from human)
- Surfeit locus protein 6 (41 kDa, Protein from human)
- Atp-dependent rna helicase ddx18 (75 kDa, Protein from human)
- 60s ribosomal protein l18a (20 kDa, Protein from human)
- 60s ribosomal protein l17 (21 kDa, Protein from human)
- 60s ribosomal protein l13a (23 kDa, Protein from human)
- Protein mak16 homolog (35 kDa, Protein from human)
- 5.8s rrna (50 kDa, RNA from human)
- 60s ribosomal protein l23 (14 kDa, Protein from human)
- Gtp-binding protein 4 (74 kDa, Protein from human)
- 60s ribosomal protein l4 (47 kDa, Protein from human)
- Eukaryotic translation initiation factor 6 (26 kDa, Protein from human)
- Guanine nucleotide-binding protein-like 3 (62 kDa, Protein from human)
- 60s ribosomal protein l27a (16 kDa, Protein from human)
- Magnesium ion (24 Da, Ligand)
Human nucleolar pre-60S ribosomal subunit (State B2) - Composite map
Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 8fks
Q-score: 0.498
Science (2023) 381 pp. eadh3892-eadh3892 [ Pubmed: 37410842 DOI: doi:10.1126/science.adh3892 ]
- 60s ribosomal protein l12 (17 kDa, Protein from human)
- 60s ribosomal protein l21 (18 kDa, Protein from human)
- 60s ribosomal protein l14 (23 kDa, Protein from human)
- 60s ribosomal protein l26 (17 kDa, Protein from human)
- Ribosome biogenesis protein bop1 (83 kDa, Protein from human)
- Ribosome biogenesis protein nsa2 homolog (30 kDa, Protein from human)
- 60s ribosomal protein l37 (11 kDa, Protein from human)
- Pre-rrna 2'-o-ribose rna methyltransferase ftsj3 (96 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- 60s ribosomal protein l6 (32 kDa, Protein from human)
- Nucleolar protein 16 (21 kDa, Protein from human)
- 60s ribosomal protein l7-like 1 (29 kDa, Protein from human)
- Pescadillo homolog (68 kDa, Protein from human)
- 28s rrna (1 MDa, RNA from human)
- 60s ribosomal protein l3 (46 kDa, Protein from human)
- 60s ribosomal protein l35a (12 kDa, Protein from human)
- Probable ribosome biogenesis protein rlp24 (19 kDa, Protein from human)
- Suppressor of swi4 1 homolog (53 kDa, Protein from human)
- Mrna turnover protein 4 homolog (27 kDa, Protein from human)
- Potassium ion (39 Da, Ligand)
- 60s ribosomal protein l15 (24 kDa, Protein from human)
- Mki67 fha domain-interacting nucleolar phosphoprotein (34 kDa, Protein from human)
- 60s ribosomal protein l23a (17 kDa, Protein from human)
- Rrp15-like protein (31 kDa, Protein from human)
- Ribosome biogenesis protein brx1 homolog (41 kDa, Protein from human)
- 60s ribosomal protein l35 (14 kDa, Protein from human)
- 60s ribosomal protein l32 (15 kDa, Protein from human)
- 60s ribosomal protein l18 (21 kDa, Protein from human)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- 60s ribosomal protein l7 (29 kDa, Protein from human)
- 60s ribosomal protein l7a (30 kDa, Protein from human)
- Ribosome biogenesis regulatory protein homolog (41 kDa, Protein from human)
- Ribosomal l1 domain-containing protein 1 (55 kDa, Protein from human)
- 60s ribosomal protein l9 (21 kDa, Protein from human)
- 60s ribosomal protein l13 (24 kDa, Protein from human)
- Probable rrna-processing protein ebp2 (34 kDa, Protein from human)
- 60s ribosomal protein l36 (12 kDa, Protein from human)
- Its2 rrna (376 kDa, RNA from human)
- Surfeit locus protein 6 (41 kDa, Protein from human)
- Atp-dependent rna helicase ddx18 (75 kDa, Protein from human)
- 60s ribosomal protein l18a (20 kDa, Protein from human)
- 60s ribosomal protein l28 (15 kDa, Protein from human)
- 60s ribosomal protein l17 (21 kDa, Protein from human)
- 60s ribosomal protein l13a (23 kDa, Protein from human)
- Gtp-binding protein 4 (74 kDa, Protein from human)
- 5.8s rrna (50 kDa, RNA from human)
- 60s ribosomal protein l23 (14 kDa, Protein from human)
- Human nucleolar pre-60s ribosomal subunit (state b2) (Complex from Homo sapiens)
- 60s ribosomal protein l4 (47 kDa, Protein from human)
- Eukaryotic translation initiation factor 6 (26 kDa, Protein from human)
- 60s ribosomal protein l27a (16 kDa, Protein from human)
- Magnesium ion (24 Da, Ligand)
Human nucleolar pre-60S ribosomal subunit (State C1) - Composite map
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 8fkt
Q-score: 0.524
Science (2023) 381 pp. eadh3892-eadh3892 [ Pubmed: 37410842 DOI: doi:10.1126/science.adh3892 ]
- Ribosome production factor 1 (40 kDa, Protein from human)
- 60s ribosomal protein l12 (17 kDa, Protein from human)
- 60s ribosomal protein l21 (18 kDa, Protein from human)
- 60s ribosomal protein l14 (23 kDa, Protein from human)
- 60s ribosomal protein l26 (17 kDa, Protein from human)
- Protein llp homolog (15 kDa, Protein from human)
- Ribosome biogenesis protein bop1 (83 kDa, Protein from human)
- Ribosome biogenesis protein nsa2 homolog (30 kDa, Protein from human)
- 60s ribosomal protein l37 (11 kDa, Protein from human)
- Ribosomal rna processing protein 1 homolog a (52 kDa, Protein from human)
- Pre-rrna 2'-o-ribose rna methyltransferase ftsj3 (96 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- 60s ribosomal protein l6 (32 kDa, Protein from human)
- Nucleolar protein 16 (21 kDa, Protein from human)
- 60s ribosomal protein l7-like 1 (29 kDa, Protein from human)
- Pescadillo homolog (68 kDa, Protein from human)
- 28s rrna (1 MDa, RNA from human)
- 60s ribosomal protein l3 (46 kDa, Protein from human)
- 60s ribosomal protein l35a (12 kDa, Protein from human)
- Probable ribosome biogenesis protein rlp24 (19 kDa, Protein from human)
- Wd repeat-containing protein 74 (42 kDa, Protein from human)
- Mrna turnover protein 4 homolog (27 kDa, Protein from human)
- Potassium ion (39 Da, Ligand)
- 60s ribosomal protein l15 (24 kDa, Protein from human)
- Atp-dependent rna helicase ddx54 (98 kDa, Protein from human)
- Mki67 fha domain-interacting nucleolar phosphoprotein (34 kDa, Protein from human)
- 60s ribosomal protein l10a (24 kDa, Protein from human)
- 60s ribosomal protein l23a (17 kDa, Protein from human)
- Ribosome biogenesis protein brx1 homolog (41 kDa, Protein from human)
- Probable 28s rrna (cytosine(4447)-c(5))-methyltransferase (89 kDa, Protein from human)
- 60s ribosomal protein l35 (14 kDa, Protein from human)
- 60s ribosomal protein l32 (15 kDa, Protein from human)
- Iron/sulfur cluster (351 Da, Ligand)
- 60s ribosomal protein l18 (21 kDa, Protein from human)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- 60s ribosomal protein l7 (29 kDa, Protein from human)
- 60s ribosomal protein l7a (30 kDa, Protein from human)
- Ribosome biogenesis regulatory protein homolog (41 kDa, Protein from human)
- Ribosomal l1 domain-containing protein 1 (55 kDa, Protein from human)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- 60s ribosomal protein l9 (21 kDa, Protein from human)
- Human nucleolar pre-60s ribosomal subunit (state c1) (Complex from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from human)
- Probable rrna-processing protein ebp2 (34 kDa, Protein from human)
- 60s ribosomal protein l36 (12 kDa, Protein from human)
- Its2 rrna (376 kDa, RNA from human)
- 60s ribosome subunit biogenesis protein nip7 homolog (20 kDa, Protein from human)
- Atp-dependent rna helicase ddx18 (75 kDa, Protein from human)
- 60s ribosomal protein l18a (20 kDa, Protein from human)
- 60s ribosomal protein l17 (21 kDa, Protein from human)
- 60s ribosomal protein l13a (23 kDa, Protein from human)
- Protein mak16 homolog (35 kDa, Protein from human)
- 5.8s rrna (50 kDa, RNA from human)
- 60s ribosomal protein l23 (14 kDa, Protein from human)
- Gtp-binding protein 4 (74 kDa, Protein from human)
- 60s ribosomal protein l4 (47 kDa, Protein from human)
- Eukaryotic translation initiation factor 6 (26 kDa, Protein from human)
- Guanine nucleotide-binding protein-like 3 (62 kDa, Protein from human)
- 60s ribosomal protein l27a (16 kDa, Protein from human)
- Magnesium ion (24 Da, Ligand)