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sample_name:"26S proteasome regulatory subunit 8"
Proteasome-ZFAND5 Complex Z+A state
Release date: Feb. 8, 2023
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7qxn
Q-score: 0.319
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7qxn
Q-score: 0.319
To Be Published
Sample:
- 26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from Homo sapiens)
- Isoform long of proteasome subunit alpha type-1 (30 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from Homo sapiens)
- Proteasome-zfand5 complex z+a state (Complex from Homo sapiens)
- Isoform 2 of 26s proteasome regulatory subunit 8 (44 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 4 (49 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 6a (49 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-7 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 7 (48 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 6b (47 kDa, Protein from Homo sapiens)
- 26s proteasome complex subunit sem1 (8 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- 26s proteasome regulatory subunit 10b (45 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from Homo sapiens)
Proteasome-ZFAND5 Complex Z+B state
Release date: Feb. 8, 2023
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7qxp
Q-score: 0.336
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7qxp
Q-score: 0.336
To Be Published
Sample:
- 26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from Homo sapiens)
- Isoform long of proteasome subunit alpha type-1 (30 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from Homo sapiens)
- Isoform 2 of 26s proteasome regulatory subunit 8 (44 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 4 (49 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 6a (49 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
- Human proteasome zfand5 complex z+b state (Complex from Homo sapiens)
- Proteasome subunit beta type-7 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 7 (48 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 6b (47 kDa, Protein from Homo sapiens)
- 26s proteasome complex subunit sem1 (8 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- 26s proteasome regulatory subunit 10b (45 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from Homo sapiens)
Proteasome-ZFAND5 Complex Z+C state
Release date: Feb. 8, 2023
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7qxu
Q-score: 0.233
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7qxu
Q-score: 0.233
To Be Published
Sample:
- 26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from human)
- Isoform long of proteasome subunit alpha type-1 (30 kDa, Protein from human)
- Proteasome subunit beta type-6 (25 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from human)
- Proteasome subunit alpha type-5 (26 kDa, Protein from human)
- Proteasome subunit alpha type-7 (27 kDa, Protein from human)
- Proteasome subunit beta type-4 (29 kDa, Protein from human)
- Proteasome subunit beta type-7 (29 kDa, Protein from human)
- Proteasome subunit alpha type-2 (25 kDa, Protein from human)
- Proteasome subunit beta type-5 (28 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from human)
- 26s protease regulatory subunit 6b (47 kDa, Protein from human)
- 26s proteasome regulatory subunit 10b (45 kDa, Protein from human)
- 26s proteasome regulatory subunit 4 (48 kDa, Protein from human)
- 26s proteasome regulatory subunit 8 (43 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from human)
- Proteasome subunit beta type-2 (22 kDa, Protein from human)
- Proteasome subunit alpha type-4 (29 kDa, Protein from human)
- 26s protease regulatory subunit 6a (49 kDa, Protein from human)
- Proteasome subunit alpha type-6 (27 kDa, Protein from human)
- Proteasome subunit alpha type-3 (28 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from human)
- Human proteasome zfand5 complex z+c state (Complex from Homo sapiens)
- 26s proteasome complex subunit sem1 (8 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- 26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from human)
- Proteasome subunit beta type-1 (26 kDa, Protein from human)
- 26s protease regulatory subunit 7 (48 kDa, Protein from human)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Proteasome subunit beta type-3 (22 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from human)
- Magnesium ion (24 Da, Ligand)
- 26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from human)
Proteasome-ZFAND5 Complex Z+D state
Release date: Feb. 8, 2023
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7qxw
Q-score: 0.267
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7qxw
Q-score: 0.267
To Be Published
Sample:
- 26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from human)
- Isoform long of proteasome subunit alpha type-1 (30 kDa, Protein from human)
- Proteasome subunit beta type-6 (25 kDa, Protein from human)
- Isoform 2 of 26s proteasome regulatory subunit 8 (44 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from human)
- Human proteasome zfand5 complex z+d state (Complex from Homo sapiens)
- Proteasome subunit alpha type-5 (26 kDa, Protein from human)
- Proteasome subunit alpha type-7 (27 kDa, Protein from human)
- Proteasome subunit beta type-4 (29 kDa, Protein from human)
- 26s proteasome regulatory subunit 4 (48 kDa, Protein from human)
- Proteasome subunit beta type-7 (29 kDa, Protein from human)
- Proteasome subunit alpha type-2 (25 kDa, Protein from human)
- Proteasome subunit beta type-5 (28 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from human)
- 26s protease regulatory subunit 6b (47 kDa, Protein from human)
- 26s proteasome regulatory subunit 10b (45 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from human)
- Proteasome subunit beta type-2 (22 kDa, Protein from human)
- Proteasome subunit alpha type-4 (29 kDa, Protein from human)
- 26s protease regulatory subunit 6a (49 kDa, Protein from human)
- Proteasome subunit alpha type-6 (27 kDa, Protein from human)
- Proteasome subunit alpha type-3 (28 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from human)
- 26s proteasome complex subunit sem1 (8 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- 26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from human)
- Proteasome subunit beta type-1 (26 kDa, Protein from human)
- 26s protease regulatory subunit 7 (48 kDa, Protein from human)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Proteasome subunit beta type-3 (22 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from human)
- An1-type zinc finger protein 5 (23 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from human)
Proteasome-ZFAND5 Complex Z+E state
Release date: Feb. 8, 2023
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 7qxx
Q-score: 0.233
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 7qxx
Q-score: 0.233
To Be Published
Sample:
- 26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from human)
- Isoform long of proteasome subunit alpha type-1 (30 kDa, Protein from human)
- Proteasome subunit beta type-6 (25 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from human)
- Human proteasome zfand5 complex z+b state (Complex from Homo sapiens)
- Proteasome subunit alpha type-5 (26 kDa, Protein from human)
- Proteasome subunit alpha type-7 (27 kDa, Protein from human)
- Proteasome subunit beta type-4 (29 kDa, Protein from human)
- Proteasome subunit beta type-7 (29 kDa, Protein from human)
- Proteasome subunit alpha type-2 (25 kDa, Protein from human)
- Proteasome subunit beta type-5 (28 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from human)
- 26s protease regulatory subunit 6b (47 kDa, Protein from human)
- 26s proteasome regulatory subunit 10b (45 kDa, Protein from human)
- 26s proteasome regulatory subunit 4 (48 kDa, Protein from human)
- 26s proteasome regulatory subunit 8 (43 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from human)
- Proteasome subunit beta type-2 (22 kDa, Protein from human)
- Proteasome subunit alpha type-4 (29 kDa, Protein from human)
- 26s protease regulatory subunit 6a (49 kDa, Protein from human)
- Proteasome subunit alpha type-6 (27 kDa, Protein from human)
- Proteasome subunit alpha type-3 (28 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from human)
- 26s proteasome complex subunit sem1 (8 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- 26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from human)
- Proteasome subunit beta type-1 (26 kDa, Protein from human)
- 26s protease regulatory subunit 7 (48 kDa, Protein from human)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Proteasome subunit beta type-3 (22 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from human)
- Magnesium ion (24 Da, Ligand)
- 26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from human)
Proteasome-ZFAND5 Complex Z-B state
Release date: Feb. 8, 2023
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 7qya
Q-score: 0.176
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 7qya
Q-score: 0.176
To Be Published
Sample:
- 26s protease regulatory subunit 4 (49 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from human)
- Isoform long of proteasome subunit alpha type-1 (30 kDa, Protein from human)
- Proteasome subunit beta type-6 (25 kDa, Protein from human)
- Isoform 2 of 26s proteasome regulatory subunit 8 (44 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from human)
- Proteasome subunit alpha type-5 (26 kDa, Protein from human)
- Proteasome subunit alpha type-7 (27 kDa, Protein from human)
- Proteasome subunit beta type-4 (29 kDa, Protein from human)
- Proteasome subunit beta type-7 (29 kDa, Protein from human)
- Human proteasome zfand5 complex z-b state (Complex from Homo sapiens)
- Proteasome subunit alpha type-2 (25 kDa, Protein from human)
- Proteasome subunit beta type-5 (28 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from human)
- 26s protease regulatory subunit 6b (47 kDa, Protein from human)
- 26s proteasome regulatory subunit 10b (45 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from human)
- Proteasome subunit beta type-2 (22 kDa, Protein from human)
- Proteasome subunit alpha type-4 (29 kDa, Protein from human)
- 26s protease regulatory subunit 6a (49 kDa, Protein from human)
- Proteasome subunit alpha type-6 (27 kDa, Protein from human)
- Proteasome subunit alpha type-3 (28 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from human)
- 26s proteasome complex subunit sem1 (8 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- 26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from human)
- Proteasome subunit beta type-1 (26 kDa, Protein from human)
- 26s protease regulatory subunit 7 (48 kDa, Protein from human)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Proteasome subunit beta type-3 (22 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from human)
Proteasome-ZFAND5 Complex Z-C state
Release date: Feb. 8, 2023
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7qyb
Q-score: 0.252
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7qyb
Q-score: 0.252
To Be Published
Sample:
- 26s protease regulatory subunit 4 (49 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from human)
- Isoform long of proteasome subunit alpha type-1 (30 kDa, Protein from human)
- Proteasome subunit beta type-6 (25 kDa, Protein from human)
- Isoform 2 of 26s proteasome regulatory subunit 8 (44 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from human)
- Proteasome subunit alpha type-5 (26 kDa, Protein from human)
- Proteasome subunit alpha type-7 (27 kDa, Protein from human)
- Proteasome subunit beta type-4 (29 kDa, Protein from human)
- Proteasome subunit beta type-7 (29 kDa, Protein from human)
- Proteasome subunit alpha type-2 (25 kDa, Protein from human)
- Proteasome subunit beta type-5 (28 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from human)
- 26s protease regulatory subunit 6b (47 kDa, Protein from human)
- 26s proteasome regulatory subunit 10b (45 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from human)
- Proteasome subunit beta type-2 (22 kDa, Protein from human)
- Proteasome subunit alpha type-4 (29 kDa, Protein from human)
- 26s protease regulatory subunit 6a (49 kDa, Protein from human)
- Proteasome subunit alpha type-6 (27 kDa, Protein from human)
- Proteasome subunit alpha type-3 (28 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from human)
- 26s proteasome complex subunit sem1 (8 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- 26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from human)
- Proteasome subunit beta type-1 (26 kDa, Protein from human)
- 26s protease regulatory subunit 7 (48 kDa, Protein from human)
- Human proteasome zfand5 complex z-c state (Complex from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Proteasome subunit beta type-3 (22 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from human)
- 26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from human)
- Magnesium ion (24 Da, Ligand)
- 26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from human)
Structure of USP14-bound human 26S proteasome in substrate-inhibited state SB_USP14
Release date: May 18, 2022
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7w3i
Q-score: 0.358
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7w3i
Q-score: 0.358
Zhang S, Zou S, Yin D, Zhao L, Finley D, Wu Z, Mao Y
Nature (2022) 605 pp. 567-574 [ Pubmed: 35477760 DOI: doi:10.1038/s41586-022-04671-8 ]
Sample:
- 26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from Homo sapiens)
- Isoform 2 of 26s proteasome regulatory subunit 8 (44 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 4 (49 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 6a (49 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from Homo sapiens)
- Usp14 (Complex)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-7 (30 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 7 (48 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
- 26s proteasome (Complex from Homo sapiens)
- 26s protease regulatory subunit 6b (47 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
- Ubiquitin (8 kDa, Protein from Homo sapiens)
- Ubiquitin carboxyl-terminal hydrolase 14 (56 kDa, Protein from Homo sapiens)
- 26s proteasome (1 MDa, Complex from Homo sapiens)
- Isoform long of proteasome subunit alpha type-1 (30 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- 26s proteasome regulatory subunit 10b (45 kDa, Protein from Homo sapiens)
- 26s proteasome complex subunit dss1 (8 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 3 (61 kDa, Protein from Homo sapiens)
Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD5_USP14
Release date: May 18, 2022
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7w3m
Q-score: 0.325
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7w3m
Q-score: 0.325
Zhang S, Zou S, Yin D, Zhao L, Finley D, Wu Z, Mao Y
Nature (2022) 605 pp. 567-574 [ Pubmed: 35477760 DOI: doi:10.1038/s41586-022-04671-8 ]
Sample:
- 26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from Homo sapiens)
- Isoform 2 of 26s proteasome regulatory subunit 8 (44 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 4 (49 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 6a (49 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-7 (30 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 7 (48 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
- 26s proteasome (Complex from Homo sapiens)
- 26s protease regulatory subunit 6b (47 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
- Sd5_usp14 (Complex)
- Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
- Ubiquitin (8 kDa, Protein from Homo sapiens)
- Ubiquitin carboxyl-terminal hydrolase 14 (56 kDa, Protein from Homo sapiens)
- 26s proteasome (1 MDa, Complex from Homo sapiens)
- Isoform long of proteasome subunit alpha type-1 (30 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- 26s proteasome regulatory subunit 10b (45 kDa, Protein from Homo sapiens)
- 26s proteasome complex subunit dss1 (8 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 3 (61 kDa, Protein from Homo sapiens)
Structure of USP14-bound human 26S proteasome in state EA1_UBL
Release date: May 4, 2022
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7w37
Q-score: 0.444
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7w37
Q-score: 0.444
Zhang S, Zou S, Yin D, Zhao L, Finley D, Wu Z, Mao Y
Nature (2022) 605 pp. 567-574 [ Pubmed: 35477760 DOI: doi:10.1038/s41586-022-04671-8 ]
Sample:
- 26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from Homo sapiens)
- Isoform 2 of 26s proteasome regulatory subunit 8 (44 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 4 (49 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 6a (49 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-7 (30 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 7 (48 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
- 26s protease regulatory subunit 6b (47 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
- Ubiquitin carboxyl-terminal hydrolase 14 (56 kDa, Protein from Homo sapiens)
- 26s proteasome (1 MDa, Complex from Homo sapiens)
- Isoform long of proteasome subunit alpha type-1 (30 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 2 (100 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- 26s proteasome regulatory subunit 10b (45 kDa, Protein from Homo sapiens)
- 26s proteasome complex subunit dss1 (8 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from Homo sapiens)
- 26s proteasome non-atpase regulatory subunit 3 (61 kDa, Protein from Homo sapiens)